Wait a second!
More handpicked essays just for you.
More handpicked essays just for you.
The ethical dilemma of designer babies | Paul Knoepfler review
Unethical designer babies
Unethical designer babies
Don’t take our word for it - see why 10 million students trust us with their essay needs.
The genetic engineering of human embryos is unethical, and is harmful to the biological and social constructs of the human race. An embryo that has been genetically modified, more commonly known as a “designer baby”, is a baby whose genetic makeup has been altered to make sure a certain gene is either present or absent. This is done by editing the DNA in the genes of the embryo in its earliest development stages. The egg is fertilized by the sperm outside of the womb, and is then implanted into the womb to continue development. Recently, a process called CRISPR-CAS9 which uses endonucleases or enzymes that cut DNA at specific locations has been developed.
Rather than relying on bacteria to generate CRISPR RNAs, scientists first design and synthesize short RNA molecules that match a specific DNA sequence—for example, in a human cell. Then, like in the targeting step of the bacterial system, this ‘guide RNA’ shuttles molecular machinery to the intended DNA target. Once localized to the DNA region of interest, the molecular machinery can silence a gene or even change the sequence of a gene! This type of gene editing can be likened to editing a sentence with a word processor to delete words or correct spelling mistakes. [1]
The CRISPR-associated protein Cas9 is an endonuclease that uses a guide sequence within an RNA duplex, tracrRNA:crRNA, to form base pairs with DNA target sequences, enabling Cas9 to introduce a site-specific double-strand break in the DNA. The dual tracrRNA:crRNA was engineered as a single guide RNA (sgRNA) that retains two critical features: a sequence at the 5′ side that determines the DNA target site by Watson-Crick base-pairing and a duplex RNA structure at the 3′ side that binds to Cas9. This finding created a...
... middle of paper ...
...s who would have otherwise inherited traits for genetic illnesses, that particular illness could be stopped. It would also allow parents to have healthy children related to the both of them. Although a social divide is very possible and a great risk, the future cannot be predicted and it is not certain that inequality and social problems will occur. However, since genetic modification is not available today nor will be in the very near future, it is not possible to know all of the possible effects of it. To even make designer babies possible, scientists still need to find ways that will ensure the genetically modified embryos do even so much as survive after the modification. Even if it were possible, there are many unavoidable side effects we have not yet encountered. For this reason, genetic modification is not something we should strive towards as a society today.
A person's individuality begins at conception and develops throughout life. These natural developments can now be changed through genetically engineering a human embryo. Through this process, gender, eye and hair color, height, medical disorders, and many more qualities can be changed. I believe genetically engineering a human embryo is corrupt because it is morally unacceptable, violates the child's rights, and creates an even more divided society.
SUMMARY: Director of the Ethics Institute, Ronald M. Green, in his article “Building Baby from the Genes Up” discusses why he thinks that genetically modifying babies genes is more beneficial than destructive. He begins his article off by mentioning a story of a couple who wishe to genetically modify their baby so that they could make sure the baby would not develop the long family line of breast cancer. Green then notifies the reader that no matter where they stand on the matter, genetically modifying babies is going to become more and more popular. Even the National Institute of Health is beginning to invest in technology that can be used to genetically modify human genes. He then explains how genetically modifying human genes can be beneficial,
After the discovery of genetically altering an embryo before implantation, “designer babies” was coined to describe a child genetically altered “to ensure specific intellectual and cosmetic characteristics.” (“Designer Babies” n.p.). This procedure combines genetic engineering and In Vitro Fertilization (IVF) to make sure certain characteristics are absent or present in an embryo (Thadani n.p.). The procedure also includes taking an embryo to be pre-implementation genetically diagnosed (PGD), another procedure that doctors use to screen the embryos (Stock n.p.). An embryo’s DNA goes through multiple tests to obtain an analysis of the embryo, which will list all the components of the embryo including genetic disorders and physical traits such as Down syndrome, blue eyes, and brown hair, for instance (Smith 7). Although the use of PGD is widely accepted by the “reproductive medical community” and the modifying of disorders or diseases is to a degree, once the characteristics are no longer health related “72% disapprove of the procedure” (“Designer Babies” n.p.). At this point the parents make decisions that would alter their child’s life forever and this decision is rather controversial in the U...
Late one night a woman is driving home on the freeway, she’s hit head on by a drunk driver and killed. The man is charged with two accounts of murder; the woman, and her four-week-old embryo inside her. By law, everyone human being is guaranteed rights of life; born or unborn they are equal. The same law should be enforced concerning human embryonic stem cell research. Dr. James A. Thomson discovered stem cells in 1998 and they’ve intrigued scientist ever since. The stem cells themselves are derived from a three to four day old cluster of cells called a blastocyst and they are so coveted because they are pluripotent, meaning they can differentiate into any type of cell in the human body. Although embryonic stem cells show amazing potential to cure various disease such as cancer, congestive heart failure, Alzheimer’s and Parkinson’s disease, muscular dystrophies, and more. The methods by which they are obtained is controversial. Research on embryonic stem cells is unethical, unnecessary, and purely homicide.
What do one think of when they hear the words “Designer Babies”? A couple designing their own baby of course, and it’s become just that. Technology has made it possible for there to be a way for doctors to modify a babies characteristics and its health. Genetically altering human embryos is morally wrong, and can cause a disservice to the parents and the child its effecting.
Picture a young couple in a waiting room looking through a catalogue together. This catalogue is a little different from what you might expect. In this catalogue, specific traits for babies are being sold to couples to help them create the "perfect baby." This may seem like a bizarre scenario, but it may not be too far off in the future. Designing babies using genetic enhancement is an issue that is gaining more and more attention in the news. This controversial issue, once thought to be only possible in the realm of science-fiction, is causing people to discuss the moral issues surrounding genetic enhancement and germ line engineering. Though genetic research can prove beneficial to learning how to prevent hereditary diseases, the genetic enhancement of human embryos is unethical when used to create "designer babies" with enhanced appearance, athletic ability, and intelligence.
Scientists have edited the DNA of non- viable embryos. It is argued that it’s the first step for parents being able to design their own children. Sarah Knapton (April 23) stresses the risks of Genetic Engineering by questioning the motivations of Genetic scientists. By stating that these genetic scientists want their names in a history books. Genetic engineering implies ethical issues and safety issues. Oxford professor conducted a test. 71 embryos survived and 54 were genetically tested. 28 were spliced and some of the contained a replacement genetic material. It was found that there was unexpected mutations that shouldn’t off been effected by the technique. However, the Chinese scientist states that the embryos were non-viable. Is this a safe practice if the researchers are contradicting themselves? Universal laws guided by ideologies that help promote the health and wellbeing of society using principles of equality and justice. Equality and justice are two values that need to be incorporated in this practice to make sure the focus on genetic engineering will be utilized for life saving reasons.
People should not have access to genetically altering their children because of people’s views on God and their faith, the ethics involving humans, and the possible dangers in tampering with human genes. Although it is many parent’s dream to have the perfect child, or to create a child just the way they want, parents need to realize the reality in genetic engineering. Sometimes a dream should stay a figment of one’s imagination, so reality can go in without the chance of harming an innocent child’s life.
Genetic Engineering has recently become a contentious topic within medical and social circles. Controversial topics such as Sex Selection and Designer Babies are linked to Genetic engineering. They are destructive in every circumstance. Genetic Engineering is detrimental towards the individual and all posterity.
The sequences of CRISPR were first discovered in 1987, when scientists reading genetic code found five identical segments of DNA separated by bits of DNA that match that of a virus. CRISPR, which is a specialized strand of DNA, stands for clustered regularly interspaced short palindromic repeats. It can be used as a defense system to “cut out” and destroy virus DNA and unwanted genes. It is the most powerful genetic engineering technology ever discovered, and harnessing and using it could have both powerful benefits and dire consequences.
If a limit is not set between using genetic engineering for treatment and using genetic engineering for enhancement, then many parents could use it purely for eugenic purposes. This could cause ethical concerns but social concerns as well. If this was allowed to occur, it would also give the rich even more advantages than they already have to begin with and drive the social classes even farther apart. The use of genetic engineering may also lead to genetic discrimination. As in the movie Gattaca, a person could easily get a print-out of his or her genotype, this information could then be used by schools, employers, companies, and others; giving rise to a new form of discrimination based on a person’s genetic profile. As the world is already full of discrimination, genetic engineering would even increase the numbers of discrimination against people.
This technology is a huge discovery and I think we need to research every possible aspect of this technology to discover all of its capabilities. A problem I for see in the future with CRISPR is scientists knowing when to use it and identifying when it is being used appropriately, especially in relation to editing the human genome. It’ll be hard to distinguish what genetic disorders and other genetic abnormalities are severe enough to try and delete from the genome. This technology in general is very new and the affects from CRISPR cannot be examined in full because there has not been enough time to demonstrate these affects. It’s also a downside that many organisms do not have all their genomes sequenced for this gene editing to be successful. There is so much at stake when CRISPR is used to edit human genomes and a major risk assessment is needed to ensure that new mutations are not introduced into the population. If researcher’s use CRISPR/Cas 9 appropriately and have demonstrated that there are ways to edit organisms’ genomes without causing harm to the individual or associated population, I would not be surprised if there were human clinical trials that use CRISPR to try and improve human
Many scientists and innovators alike are asking “What would it be like to have a baby? Or even a baby that you designed? This baby having no diseases and to cure your diseases in addition, all with the same process.” Well this can all be yours with the likely unavoidable side effects of this DNA cutting and insertion. Although, while this new and groundbreaking technology, known as CRISPR/Cas has only been used widely for three years. During, this short span of wide use it has gained overwhelming traction and controversy. The audience that this technology draws can be strongly attributed to this topic’s controversial core and its possibilities for the future.
“UC Berkeley researchers have made a major improvement in CRISPR-Cas9 technology that achieves an unprecedented success rate of 60 percent when replacing a short stretch of DNA with another”(Antonio Carusillo, PhD Candidate in Genetic Engineering (Marie Curie) at University of Freiburg (2018-present). This statistic shows that there is more of a chance to success but there is a chance to fail 40 percent but overall it will succeed which is why people are lenient about will it actually work or not, but as technology get better so will treatments to cure hard to pinpoint disease such as cancer, zika, or leukemia. Genome editing (also called gene editing) is a group of technologies that give scientists the ability to change an organism's DNA.
Although genetic engineering seems to be more harmful than helpful, when used correctly, it will help the society prosper. Considering the technology our society has currently developed, genetic engineering is a difficult topic to discuss and confirm. If the researchers confirm this process, it may become easier for the scientists and will help cure the diseases easily. The debate, however, will still be on the rise because of the issue in human morals and ethics.