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Short essay on importance of sleep
MAIN POINTS OF WHY importance of sLEEP
An essay about the importance of sleep
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I. Introduction
Sleep is of quintessential importance in our daily lives. Prolonged sleep deprivation can result in decreased immune system and in the worst case scenario death. As everyone can relate to, our sleep-wake cycle is relatively regular and stable, and there is a reason for our regular biological cycles: the suprachiasmatic nucleus (SCN). In our body, multiple biological clocks regulate circadian rhythms like our sleep-wake cycle and rhythms of hormonal release. Within the hypothalamus, the suprachiasmatic nucleus (SCN) contains the master clock that regulates the peripheral circadian clocks in the brain to prevent them from going out of sync with each other. The SCN also receives information from the retina for light entrainment and thus maintains the whole system in synchrony with the light-dark (LD) cycle. It has been the central dogma in the field of circadian biology that light is the primary zeitgeber, cue that entrains the circadian rhythm. Many studies show that daytime neuronal activity of the SCN and light-induced neuronal activity of the SCN inhibit locomotor activity in nocturnal rodents. However, several studies show that the food anticipatory behavior (FAA), which is induced by limiting food to a few hours a day, can be zeitgeber that supersedes all other cues, including light. Rodents can anticipate a predictable daily mealtime by entrainment of circadian oscillators. Studies show that this anticipatory behavior does not require the master circadian clock within the SCN and this has led to the hypothesis that there are food-entrainable oscillators (FEOs) in the brain responsible for the anticipatory behavior. However, the circadian oscillators responsible for the FAA are still unknown. In this paper, I ...
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...may not seem practical, it could shed some new light on the location of FEOs. Furthermore, more tests need to be done using different clock genes in order to determine if DMH is truly involved with FAA or simply downstream to other circadian oscillators that determine the FAA. If there are actually multiple FEOs in play, as proposed by Feillet et al. (2008), then there needs to be experiments combining lesions in multiple sites to produce impairments of FAA (Feillet and Mendoza, 2007). Again, because the answer is open to endless possibilities, I also participated in the research trying to locate the FEOs. However, my results did not yield any significant rhythms in the DMH when we performed in situ hybridization targeting the clock gene Baml1. Upon reading these articles, maybe a future research direction, even for me, will to consider FEOs other than the DMH.
The body’s internal clock, commonly known as circadian rhythm, does not sync with the DST’s clock. This disconnect between the body’s clock and the DST’s clock can engender feelings of “restlessness, sleep disruption, and shorter sleep duration” (O’Connor).
Famous and successful people like Albert Einstein and Da Vinci took naps regularly! Without his naps, Da Vinci might have never had enough energy to paint the Mona Lisa, or Albert Einstein might have never become one of the smartest people in the world. After reading what you just read above, you might feel like you should start taking naps too. However, why should someone take naps? Here is a situation: did your doctor ever recommend you to get some more rest during the night? No doubt, you obviously thought about it for a while. Regrettably, here is the problem: can you fit some more time in your schedule so that you could sleep more or do you seek an alternate way? Unfortunately, many people don’t sleep enough during the night, because of
4. Circadian Cancer Therapy. William J. M. Hrushesky, Ed. CRC Press, Inc., MI, 1994. pp 3-9, 279-281.
The notion of circadian rhythms was first documented in the eighteenth century when it was determined based on observation that the closing and opening of heliotrope plant leaves occurred independently of sunlight, which was recorded by the French astronomer de Mairan. It is clearly evident now that almost all surfaces of physiology exhibit rhythmic oscillations from the simplest of bacteria to us human beings (10). As a biological clock, circadian rhythms develop to accomplish a steady entrainment to environmental cycles such as light. Additionally, circadian rhythms also serve two main functions, which is to measure the duration of time and to track the time of the day. These two functions are intertwined with one another being that both
Although clock expression has been important to understand rhythm, the initial information from retinohypothalamic tract to core or ventro-lateral region of the SCN has been a prime focus of the recent studies. It is widely known that information from ventrolateral region of SCN communicates with other regions of the SCN. Buhr and Yoo (2010), show ventrolateral and dorsomedial neuronal connection exists and this connection has a role in circadian rythm. Their data shows that tetrodoxin can make SCN temperature incompensated due to inhibition of signal from core to shell regions. Similarly, vasoactive intestinal peptide and peptide histidine iso-leucine are expressed in SCN when light information travel from retinohypothalamic tract.
During the winter quarter of 2014, biology 155 students examined for one week circadian body rhythms during “normal” activity and rest periods. The students had to go to sleep between 10 and 12 o’clock, wake up around 6 and 8 in the morning and had to do usual activities for it to be considered a “normal” day in a week’s period. During a 24 hour period students had to interrupt their “normal” sleep period in order to collect some data. Every 2 hours, 12 times in total, three function tests were conducted in the same order and had to be written do...
We live our entire life in two states, sleep and awake1. These two states are characterized by two distinct behaviors. For instance, the brain demonstrates a well-defined activity during non-REM sleep (nREM) that is different when we are awake. In the study of sleep by Huber et. al., the authors stated that sleep is in fact a global state2. It is unclear whether this statement means that sleep is a state of global behavioural inactivity or the state of the global nervous system. The notion that sleep is a global state of the nervous system served as basis for sleep researchers to search for a sleep switch. The discovery of the sleep switch, in return, provided evidence and enhanced the notion that sleep is a global state of the nervous system. The switch hypothesis developed from the fact that sleep can be initiated without fatigue and it is reversible1. It was hypothesized that there is something in the brain that has the ability to control the whole brain and initiate sleep. Studies have found a good candidate that demonstrated this ability3. They found a group of neurons in the Ventrolateral Preoptic (VLPO) nucleus. It was a good candidate because it was active during sleep, has neuronal output that can influence the wakefulness pathway, and lesion in the area followed reduce sleep3. The idea that there is something that can control the whole brain and result sleep state supports the idea that sleep is a global state of the nervous system.
studying the subject, the origins in the brain responsible for sleep are still not fully understood and thus, facilitate continual probes
Morita, Y., Ogawa, K., & Uchida, S.(2012). The effect of a daytime 2-hour nap on complex
We experience two phases of sleep which repeat themselves every ninety to one hundred and ten minutes, achieving approximately five complete cycles per night. The phases are non- rapi...
With the mentor Rekha Balachandran, her research project is astonishing to me due to the concentration on circadian rhythm. As my background in psychology and biology, I have acknowledged that circadian rhythm is known to play a significant role in human physiological wellness. Disruption in circadian rhythm could affect metabolism poorly with the involvement of eating disorder as well as difficulties in storing information in short-term memory; improper functioni...
In a majority of circadian rhythms there seems to be major components which include an endogenous component (which is regulated by an internal clock located in the hypothalamus) and an exogenous component. This exogenous component is made up of different clues in time in the world around us....
“The current explosion of digital technology not only is changing the way we live and communicate, but is rapidly and profoundly altering our brains (Carr). When someone stays up all night staring at their cell phone, it is changing their sleep schedule. Blue enriched light that is emitted from mobile devices can suppress the body’s release of melatonin at night (Hiscott). Melatonin is the key hormone that controls someone 's internal clock, and when not enough is released, a body is oblivious to when it is supposed to be asleep. Sleep is crucial for successful development in a young child’s
We depend on sleep each and everyday in order to be able to interact throughout the day. Sleep is very important if you want to socialize with people or feel real good. It is very important in order to live a healthy life. It really gives you energy so you won’t crash. Sleep is a very important part of physical and mental health through the day.
People do not take sleep as important as they should and do not get enough sleep that their body requires to function properly. Sleep is very important for a person 's physical health, well being and healthy brain functions. Without enough sleep our bodies can not perform daily function to our full ability. For many people, sometimes there is just not enough time in one day to complete all their tasks, fulfil all responsibilities and get the minimum sleep their body requires. Why do people not get enough sleep? Being a parent, student or just an adult in the working world comes with many responsibilities. People do not get enough sleep for reasons such as stress, discomfort, or medical conditions.