Wait a second!
More handpicked essays just for you.
More handpicked essays just for you.
A good conclusion for sickle cell anemia
Abstract for sickle cell anemia
An Overview Of Sickle Cell Disease
Don’t take our word for it - see why 10 million students trust us with their essay needs.
Recommended: A good conclusion for sickle cell anemia
The problem is that sickle cell anemia affects about 72,000 Americans in the United States. Sickle cell anemia is an inherited disease in which the body is unable to produce normal hemoglobin, an iron-containing protein. Abnormal hemoglobin can morph cells that can become lodged in narrow blood vessels, blocking oxygen from reaching organs and tissues. The effects of sickle cell anemia are bouts of extreme pain, infectious, fever, jaundice, stroke, slow growth, organ, and failure.
Sickle cell anemia hurts many people today in fact it hurts about 72,000 Americans. But some doctors are finding cures for this inherited disease. This disease causes mainly strokes and fever. With this disease a stroke is not predictable, a stroke can happen as early as a one month old as a baby. It can hurt a person really bad because it causes them to not be able to do many things like can't play sports, and things that gets your heart pumping because if the red blood cells gets clogged up it can causes a stroke because oxygen can't flow. Most Americans who have sickle cell anemia are of African descent. The disease also affects Americans from the Caribbean, Central America, and parts of South America, Turkey, Greece, Italy, the Middle East and East India. Since sickle cell anemia is an inherited disease if both parents have the trait for sickle cell, their baby's chances of having sickle cell disease is one in four.
Many doctors are trying to find cures for this disease by trying the solution on patients. Doctors at Emory University and University of Mississippi Medical Center in Jackson, Chicago. Doctors in Emory University in Atlanta credited an experimental stem cell transplant that for the first time is not from a related donor. This transplant cured the inherited disease from Keone Penn who is 13 years old from Georgia. He suffered a stroke at 5 years old and had a fever of 106 degrees, "I almost died" (Ferraro, Newspaper Article) What the doctors did was replaced the boy's bone marrow with stem cells taken from the umbilical cord blood of an infant not related to him. Dr. Ruby Bellevue of New York Methodist Hospital in Brooklyn has patient that he wants to do the transplant procedure on, but he is waiting for more studies to come out to see what the long-term effects are. Some effects could be rejection, complications, and/or death.
Sickle Cell Anemia is an autosomal recessive disorder, which increases blood thickness hence affects the smooth flow of blood. This causes by the destruction of red cells where the normal shape of red cell become a stiff sickle shape. As a result, sufficient oxygen does not reach the vital organs. A vaso-occlusive crisis arises from hindrance of blood circulation by sickled blood cells. It is characterized by sturdy pains and in some cases; it may cause permanent organ damage. This paper seeks to formulate a nursing diagnosis, as well as a plan of care that includes nursing interventions and the methods to be used to evaluate whether the interventions are successful (American Sickle Cell Anemia Association).
Stem cells can be utilized by transplant. Four principal types of physical disease that can be treated with stem cell transplants, including blood disorders, congenital metabolic disorders, immunodeficiencies, and certain cancers (Waller-Wise, 2011). Some examples of diseases include Sickle-cell anemia, Tay-Sachs’ disease, Hodgkin’s and non-Hodgkin’s lymphoma, certain leukemias, and many more (Waller-Wise, 2011). It is recommended that persons with family history of any of the known diseases that can be helped with stem cell transplants consider cord blood banking. Insurance companies will need to know that funding banking for cord blood is going to have more benefits than risk.
Have you ever heard of a disorder, condition or disease for the first time wondering to yourself what it is? That was me 11 years ago when my baby girl was first diagnosed with Alpha-1 Antitrypsin Deficiency, at the young age of only four months old. My heart dropped when they told me the diagnosis even though I had no idea what it was, what is meant, or how it would change our lives. I had so many questions and even to this day, the questions still seem endless. I have spent countless hours researching and asking questions trying to fully understand what it all means. As I continue to hope and pray for a cure so my daughter can live a normal long healthy life. Although there is currently no cure for Alpha-1, recent discoveries in Stem Cell research offer hope that there could be one in the future.
What is Sickle cell disease? Sickle cell affects a disease; that disease is called which affects the hemoglobin when the red blood cells that send oxygen through the body are killed off and weakened. Sickle cells can be found in every 1 and 1000 African Americans, it is affecting about 70,000 to 80,000 Americans in the United States. Sickle cell is a death threatening disease, and the severity of symptoms can vary from person to person (Sickle cell disease (SCD), 2015). Some people have light conditions, but others can have severe conditions, which, mean they could be hospitalized. Characteristics of this disease are caused by a minimum of low blood cells, which is called anemia.
Sickle Cell Disease (SCD) (also known as Sickle Cell Disorder or Sickle Cell Anemia) is an inherited blood disorder where the red blood cells have abnormal sickle-shaped hemoglobin S (HbS) called sickle haemoglobin (National Heart Lungs and Blood Institute (NHLBI), 2015). The disease, according to medical sciences, is inherited from both parents as part of their genetic makeup and is usually caused by some abnormalities in haemoglobin which is a protein in red blood cells that conveys oxygen through the body. Whereas normal red blood cells are round, in people with sickle cell anemia, a defective substance in red blood cells changes the shape of the cells. The normal haemoglobin called haemoglobin A (HbA) is replaced by HbS which later becomes
Sickle cell anemia is a blood disorder that affects hemoglobin (pronounced: hee-muh-glow-bin), a protein found in red blood cells that helps carry oxygen throughout the body.
Imsub Monmessin, is a 22 year old student from Thailand who flew to America in order to go through gene therapy, in order to hopefully cure her inherited disorder of Beta Thalassemia. The therapy involved inserting a functional beta globin gene into a patient’s stem cells, which would alternate the cells outside of the body in order to reinsert the modified stem cells into the bloodstream, this is also known as “Autologous stem cell transplantation”. For the first 2 weeks, Imsub had to go through physical and other medical exams. Over 4 days, Imsub’s stem cells were collected and taken to a lab for another 5-6 weeks before getting her cells collected again for modification. In order to get the cells transplanted, Imsub was required to stay at the hospital for 40 days, 9 months in America with the therapy. As you see, there are a variety of therapies avaliable to prevent Beta thalassemia, despite how long processes may
Sickle cell anemia is an inherited disease of red blood cells. Normally red blood cells contain a protein called hemoglobin A, which carries oxygen to all the organs in the body. With sickle cell anemia, however, the body makes a different kind of protein, called hemoglobin S.
Sickle Cell is a disease that affects many people in the world today. It is the number one genetic disorder in the United States. Sickle Cell is deficient hemoglobin. Hemoglobin is what functions in providing oxygen to the cells in the body. The sickle shape comes from the atypical hemoglobin s molecules. Hemoglobin molecules are composed of two different parts called the alpha and beta. The beta subunit of the hemoglobin molecule has a mutation in gene, on chromosome 11 which produces the change in the red blood cell shape causing them to die and not reproduce accurately. The change in shape causes the red blood cells to get stuck in the blood vessels and block the effectiveness of oxygen transport causing pain and organ damage to the body. This disease does not have a cure and some common treatments are used to help patients live with the disease. Some treatment options are antibiotics (penicillin) to prevent infections, blood transfusions, folic acid that help produces new blood cells. These are just some of the current treatments for Sickle Cell.
She agreed to go through with this special treatment that entailed high-dose chemotherapy and then the harvesting, treating, and reimplantation of her own stem cells back into her own body. This allowed her to not need immunosuppressant drugs to lower the risk of rejection, because the stem cells are hers and would not be attacked by her own body. As a result, she was able to leave an hour after the transplant and be at her house during the recovery process as there was no risk of infection involved. As a result of this different treatment, her family saved $129,000 that would have otherwise gone to hospital bills if she would have had the normal stem cell transplant from a different donor. Overall, the cost to her family was only $250,000 compared to the $500,000 that it would have been if she had gotten a transplant from a different donor and therefore would have required an extensive hospital stay.
This article is about a family whose their daughter was struck with leukemia and the only treatment option remained was a bone marrow transplant. Anissa was terrified to discover lumps around her ankles and experienced cramp-like stomach discomforts. The diagnosis came out mysteriously that Anissa developed chronic myelogenous leukemia, which was approximated to take her life within five years or less without bone marrow transplant. Healthy stem cells from the marrow transplanted can produce healthy blood cells in the recipient’s body transplant. Both older brother and parents did not match to safe Anissa’s life. She tried to keep it secret from her parents due to fear of having to get a blood test done. The parents, Mary and Abe, were thoroughly
What a wonderful gift that would be! In 2005, Dr. Fangmann, and his medical team performed a bone marrow ACS’s transplant on a young man who had been suffering from leukemia and was undergoing chemotherapy treatment. The donor of the bone marrow was the patient's father. The patient went into remission, but his kidneys were damaged from cancer and chemotherapy complications; the young man was on dialysis for three long years until his father then donated a kidney. The son accepted the new kidney from his father and the doctors discontinued the use of immunosuppressant medication. The young man had no further health complications since the follow-up 2011 case report (pg.156,157). Clinical trials using adult stem cells are continuing to expand, especially in kidney transplants. Standford University held clinical trials on 38 patients combining two different adult stem cell blood types with kidney transplantation, and only one patient required anti-rejection medicine post-surgery due to a lupus flare-up and not organ rejection. Furthermore, Stanford University’s study provides exceptional results concerning organ acceptance even when the donor and receiver do not have well-matched antibodies in their blood (Thornley.1-3). Moreover, a blood relative is not necessary for adult stem cell therapy and organ transplantation to be successful and the medical communities' involvement demonstrates no
Sickle cell anemia is a genetically linked disorder were the red blood cells do not form properly and may cause problems due to their abnormal shape. The symptoms for sickle cell anemia is similar to other types of anemia, which may include lethargy, shortness of breath during light exercise, or dizziness and lightheadedness when active. Additionally, sickle cell sufferers may form dangerous blood clots in their veins. Although blood clots in remain in the circulatory system without causing problems for years, the blood clot may one day block a major artery in the heart or brain, which may lead to permanent organ damage or death. Fortunately, sickle cell can be tested for and does not need to be diagnosed by its symptoms. The best test for
Being afflicted with any disease or medical condition takes a toll not only to the patient but to family members as well. In general, lives of all involved change and so with the family members. The sacrifice that each one has to undertake sometimes is overwhelming. There is also the financial burden to take into consideration and the stress that goes with the ailment. Sickle cell anemia is one of the life-long diseases that is life changing. This research gives a better understanding of the condition.
The first successful case of stem cell therapy in human was reported in 1959. Bone marrow restorations were observed in leukemia patients who received total body irradiation subsequent by intravenous injection of their twins’ bone marrow (Thomas et al, 1957). Nevertheless, that effect was transient and the following bone marrow transplantation attempts in non-twin patients and donors can eventually lead to patient’s death from graft-versus-host disease (Mathé et al, 1965). During that time, the safety of hematopoietic cells transplantation was not guaranteed because of the limited knowledge in human histocompatibility and immunosuppression. However, the turning point came after the discovery of human leucocyte antigen (HLA) groups (Dausset, 1958; van Rood et al, 1958), HLA typing and compatibility testing were performed prior to the transplantation. In addition, the improvement of immunosuppressive protocol also helps bringing the bone marrow transplantation to become more and more successful (Donnall and Hutchinson, 1999).