Today I finished observing all the scaffolds using the SEM Scanning Electron Microscopy (SEM). The end goal for the non-toxic (being tested today) scaffolds is to be use as a temporary bone until the bone repairs. Then the scaffold should degrade until the bone heals properly. Also, the scaffold has to be strong, so it doesn’t break or collapse in the body that was the purpose of the mechanical testing. We have to know every properties of the scaffolds to make the scaffolds are good to be put in the body .Today we will begin testing whether the scaffold is toxic for the cells because the human body is made up of cells. We don’t want to damage the human cells. We will first use animal cells and then we will move on to human cells if the scaffolds
aren’t toxic in the animal cells. We will be using a couple of 0.8 mm Polycaprolactone (PCL) 22-layered 5 mm X 5 mm X 2 mm porous scaffolds to test toxicity. I also had to 3-D print several 0.4 mm Polycaprolactone (PCL) 22-layered 5 mm X 5 mm X 2 mm porous scaffolds because I use all the previously made scaffolds on mechanical testing. I want cells to attach to the 0.8 porous scaffolds. However, the scaffolds float on the media that will contain the cells, but since the scaffolds are porous we have to allow the media to be absorbed to be absorbed by the scaffolds so they sink in the media. Then cells can attach to the scaffolds. In order for this process to be successful it is important that I follow the procedure exactly. I will repeat this process tomorrow with the 0.4 Polycaprolactone (PCL) 22-layered 5 mm X 5 mm X 2 mm porous scaffolds that i had printed today.
No one knows for sure where the ponies came from.The chincoteague ponies stand at twelve to thirteen hands. Chincoteague ponies are stocky with short legs, thick manes, and large round bellies. Assateague island is a harsh environment for them to live and there diet is limited. We will be focusing on the Chincoteague pony roundup. You will learn about the History, The modern day, How did the book Misty of Chincoteague help the pony roundup become famous,You will also learn about the ponies on Assateague island, Finally you will learn a few quick facts about assateague island. Did you know for a horse to be considered a pony it has to stand less the 14 hands or 4.6 feet?
... The advanced technology of surface modification in the biomedical sector have the ability to offer not an improvement in the tribological properties only but also to improve the clinical requirements prior and post implantation. Such properties includes cell growth and antibacterial effect.
It’s fall everyone and Halloween is coming.I would like to tell you that fall is the best season of all.
Sophisticated methods of testing are now being applied to human cells in petri dishes. Human volunteers are also being used and micro-dose with samples so small that they do not cause adverse reactions. The argument exists that these alternative testing methods are not only more cost effective but also more relevant because they are conducted using human cells and specimens; a method that isn’t hindered by species differences. In addition, computer generated models are being used to produce virtual reconstructions in order to test toxicity.
Topic: Addiction to social media General Purpose: To persuade Specific purpose: To persuade my audience that social media is hurting us mentally and our social lives. Thesis: Social media can cause serious problems to you and your health, so we need to put addiction to social media to rest. I. Introduction A. Attention-getter: The ages of 55 and 64 year olds who use social media fell “worried or uncomfortable” when they can’t access any type of social media accounts (Wright, 2015).
These kinds of polymers have both some advantages and disadvantages. Although they are bioactive and biodegradable and provide high comppressive strength, Degradation of such polymers leads to undesired tissue response due to producing acid formation in degradation process. Metallic scaffolds are another method for bone repair and regenaration. They provide high compressive strength and enormous permanent strength. Metallic scaffolds are mainly made of titanium and talium metals. The main disadvantages of metallic scaffolds are not biodegradable and also discharge metal ions. Recent studies in metallic scaffolds mainly focus on biodegradable materials which can be used improve bioactivity of metals such as titanium.
The benefits of silica are important for connective tissue (collagen formation), development, bone, and cartilage.
... the usage of bioresorbable scaffold involves by selecting certain phenotype of cell and implants it on permeable substance before being implanted to the pulmonary position. The scaffold is presume to degenerate as the cells grow. The last approach involves constructing a mold for leaflets similar to the aortic shape using the collagen constructs (Vesely 2005).
Alternative methods are sometimes more reliable, more accurate, cost-effective, practical, and expedient Alternative testing can be used for in preclinical studies .These methods are vitro methods (human cells and tissues), silico models (advanced computer-modeling techniques), studies with human volunteers (microdosing, advanced brain imaging and recording techniques), stem cell, genetic testing methods, computerized patient-drug databases ,virtual drug trials and human-patient simulators can be used for the assessment of the safety of drugs, chemicals, cosmetics, medical devices, consumer and investigational products.
...f the product is given to a human through the skin. It is said that this could be a new and very effective alternative to Animal Experiments. Scientist have grown a small piece of human liver tissue from stem cells which might one may be possible to perform initial ‘human’ safety trails in a lab. I suppose that if the laws on the necessity for animal testing were relaxed, it would encourage the scientist to develop other methods of testing toxicity that were equally effective. There are alternatives, it is just whether or not the scientist will peruse them.
It’s winter, and your windows are frosted with ice. Snow drifts blanket your grass and summer flowers. You glance out at your car in the driveway, and you’re not exactly looking forward to the trek out there, to watching your breath as you wait for it to warm up.
Games. We all seem to enjoy them right?- I mean they bring jubilation to the participants. They are a great way of passing time and not to mention that they are immensely fun to play and if you win you end up with boasting rights.So, in general who WOULDN’T want to play games? The youngest generation is who.
I will not be here today, you can checkout with Terry. I will be at East next week (and actually until June 28) if you would like to checkout then.
Close your eyes. Imagine that you are four years old again. You are chasing your dog through the house, smiling and giggling because joy is the one thing that every four year old knows. You hear something spill on the ground, so you run to where the noise came from, stumbling upon your mother on the ground with frozen peas all around her. Unaware of what happened and still smiling, you ask her, “What’s wrong, mommy?” She starts shouting at you. When she gets close to you, a sting comes to your cheek. “This was your fault,” she says. The cycle begins. Move ahead two years. You are six years old. You just moved to a new house where you have your own room with freshly painted white walls and brand new white carpet. Within a few months,
Topic: improve, change and secure our future by matching vulnerable at-risk children with committed mentors who offer maintainable investments of time, thought and resources.