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Neuroscience personal statement
Neuroscience exploring the brain chapter 7
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In my time working alongside physicians, specifically neurologists, I have learned how imperative research is when concerning the intricacies and complexities of human physiology. Through my work as an intern alongside these neurologists, I have learned that in this specialty of clinical medicine, there can be more questions than answers. My desire to answer these questions is why I would like to engage in research and be part of the SPUR program. My passion for this science, specifically neuroscience, has intensified over my compilation of experiences.
From a very young age, my undiagnosable neurological mystery has instilled a curiosity to search for answers to deeply understand the errors in my biochemical and anatomical pathways. My unpredictable episodes of peripheral neuropathy, tingling, impaired sensation had my neurologists questioning multiple sclerosis, systemic lupus erythematosus, and Hashimoto’s thyroiditis. I went through several MRI’s, metabolic panels, and countless other tests that resulted in indefinite outcomes. Eventually, my doctors had more questions than answers. Because of this, I believe that investing myself in research will allow me to contribute to the pool of knowledge in neurology. The fact that no physician has been able to diagnosis my medical
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I was absolutely puzzled and heartbroken. Once again, there were only questions and no answers. I couldn’t fathom how a person’s brain could manifest thoughts of death. This traumatic life event propelled my driving force to seek out the “why” and “how” of the neurobiological and chemical processes a human being with the diagnosis of depression endures. This experience taught me how profound the field of neurology is: it is much more than just the physical, anatomical aspect of the central nervous system, there is also a deep psychological element present that affects us all as
In times past and recent, a person may have expressed their gratefulness to another person with a statement such as, no one expected to lose their life when they woke up today. This case of Phineas Gage is still a modern mystery to some people, in as much, the fact that he survived this horrific incident was a true blessing and a wonder for all to see. At a period in history where the brain’s activities and functions was in high debated, scientist wanting to prove their theory and every situation that involved the brain an avenue in which they used to fuel their research, Phineas gave them an enormous amount of evidence. In making the point that the brain has different lobes that has control over their respective areas and motor skills of
Through my extensive research on depression I have learned a lot of new things. I have learned about the many forms of depression and treatment for depression. I have also learned a little about what is believed to go on chemically in the brain of a clinically depressed person. I was also able to partially determine what sort of role genetics, chemicals and personal influences in the brain. Though I was unable to determine exactly how environmental and personal stress can cause a chemical imbalance in a person, I was even able to speculate about this issue and determine some theories of my own on why and how this may happen.
In 1969 Elisabeth Kübler-Ross, a psychiatrist, published the Pioneering book On Death and Dying. The work acquainted the world with the grieving process, called the five stages of grief. Kübler-Ross gathered her research from studying individuals with terminal cancer (Johnson, 2007). The first stage of the grieving process is denial. In this stage the person refuses to believe that their loved one is deceased, a common thought during this period is, “This can’t be happening to me” (Johnson, 2007).The second stage of the grieving process is anger. In this level the person becomes frustrated with their circumstances, a customary complaint is “Why is this happening to me?” (Johnson, 2007). The third stage of the grieving process is bargaining. At this point the individual hopes that they can prevent their grief, this typically involves bartering with a higher power, and an ordinary observance during this time is “I will do anything to have them back” (Johnson, 2007). The fourth and most identifiable stage of grief is depression. This phase is habitually the lengthiest as...
Depression is considered a mental disorder that can lead an individual to commit suicide, experiment fatal risk that can injure his or her life. Furthermore, an individual feeling depressed lacks motivation to do anything progressive with his or her life. With that said, these individuals sometime gives up interest in activities that were once enjoyable, gets in a phase were he or she loses appetite, begins to overeat, loses concentration on what he or she is trying to complete, and becomes indecisiveness. Moreover, depression is a condition that makes an individual feel miserable, have no motivation to any activity that can influence his or her views, actions, welfare. Furthermore, depressed individuals at times may feel sad, apprehensive, desperate, destitute, useless, awkward, short-tempered, and agitated. In addition, the melancholy of depression is categorized by a greater concentration and length that is attached to severe symptoms. According to Wedding & Corsini (2014) states, “Physical disease, severe and acute stress, and chronic stress area also precipitating factors” (Pp. 240) of an individu...
Although historically depression has been considered a character condition, evidence has accumulated suggesting the role of a biological substrate, namely serotonin, in subgroups of depressed patients. This accumulated evidence supports the indoleamine hypothesis of depression, which suggests that major depression results from a deficiency of available serotonin or inefficient serotonin. (16). We see that depletions of serotonin from certain regions of the brain such as the hypothalamus, amygdala, and cortical areas involved in cognition and other high processes, can have a great impact in contributing to depression.
Rowland, L. P., ed. Merritt’s Textbook of Neurology. 7th ed. Lea and Febiger. Philadelphia: 1984.
Burton, Neel. "The Anatomy of Melancholy: Can Depression Be Good for You?" Lecture. TEDx. Narodni Dom, Maribor. 12 Nov. 2013. Youtube. 2 Mar. 2012. Web. 12 Nov. 2013.
Major depression, in itself, is a debilitating mental disorder that negatively impacts most or all aspects of a sufferer’s life and often times can even lead to suicide. Just to give a few numbers, at least 1 million people worldwide every year take their own life (Hawton and Heeringen 1372-81), half of which are caused by the possession and improper or unsuccessful treatment of major depression (Chehil and Kutcher 30-33). In light of these dark statistics, the benefits and limitations of the main treatments for major depression, antidepressants and psychotherapy, are not only worth investigation, but with thousands of lives on line, vital to the human race. However, to take it further, there is much to be said of human nature in general as it relates to how people respond to the biological treatment of antidepressants as opposed to the cognitive and sociocultural treatment of psychotherapy. Is it possible that the various symptoms of sadness and hopelessness characteristic of major depression can be cured simply by balancing the chemical messengers in charge of happiness and motivation in the brain or must the need to be perceived and understood through therapy be satisfied? Are we, as humans, simply biological machines, or is there something more?
Leming, M., & Dickinson, G. (2011). Understanding dying, death, & bereavement. (7th ed., pp. 471-4). Belmont, California: Wadsworth.
The biologic basis of Clinical Depression originates in the brain. Your brain is made up of a complex network of nerve cells, called neurons and of brain chemicals, called neurotransmitters. Neurotransmitters transmit messages from one neuron to another. Two of these neurotransmitters are not produced in sufficient quantities in a depressed person’s brain. Because of this lack, too few messages get transmitted between neurons and the symptoms of depression occur. In Clinical depression the chemicals in the brain are out-of-balance. New technology allows researchers to take pictures of the brain that show activity levels in the brain. These imaging techniques such as f-MRI and PET scan actually create images of how active different parts of the brain are. Some studies with these kinds of techniques have suggested that the patterns of activation in the brains of depressed people are different than those who are not. These tests can help doctors and researchers learn more about depression and other mental illnesses. Since this research is fairly new, it is not yet used to diagnose clinical depression.
National Institute of Neurological Disorders and Stroke (2011). National Institutes of Health. Retrieved [18th April 2011] from http://www.ninds.nih.gov/disorders/picks/picks.htm.
Depression is well known for its mental or emotional symptoms. Symptoms for depression include: persistently sad or unhappy mood, loss of interest or pleasure in previously enjoyable activities, difficulty concentrating, remembering, making decisions, anxiety, feelings of guilt, worthlessness, helplessness, and thoughts of death or dying. “People who have endured a major depressive episode describe the experience as a descent into t...
The stages of death are known to be a process of mourning that is experienced by individuals from all phases of life. This mourning ensues from an individual’s own death or the death of a loved one. Dr. Elisabeth Kubler-Ross dedicated much of her career to studying this dying process and in turn created the five stages of death. The five stages are; denial, anger, bargaining, depression and acceptance. These stages may not occur in sequence and sometimes may intersect with one another (Axelrod, 2006). The reality of death many times causes a feeling of denial; this is known as the first stage. In this stage, people have many emotions and have a tendency to hide from reality. This reaction is momentary, but should not be rushed. The patient or loved one needs time to adjust to the awaiting death. This adjustment helps bring them through to the next stage; anger. Anger is a common feeling and many times routes from a feeling of not being ready. This emotion may be directed toward God, strangers, friends, family or even healthcare professionals (Purcell, 2006). In some cases, it can be targeted...
1. My long term research interests involve the understanding of neurological diseases and the physiological cues that regulate neural signaling (and thus behavior) based on animal circumstances. My academic training and research experience have provided me with an excellent background in multiple biological disciplines including anatomy, physiology, pharmacology, and neurobiology. As an undergraduate, I was able to conduct research with Dr. Charles Lindsey on the neuroanatomical studies projections of the paratrigeminal nucleus to the nucleus ambiguus, rostroventrolateral and lateral reticular nuclei and the solitary tract pharmacological cardiovascular effects of tachykinin NK-1 receptors using stereotaxic surgeries, blood pressure recordings,
Depression happens when all attempts to prevent the impact of the loss have failed that the reality of it begins to set in as a profound sadness and lack of direction. Depression can be seen in Alfred Lord Tennyson’s poem “In Memoriam A. H. H.” For example, in Canto 46 the speaker writes, “A lifelong tract of time reveal'd; / The fruitful hours of still increase; / Days order'd in a wealthy peace, / And those five years its richest field” (13-16). Here the speaker is saying that the five years he knew his friend were the best years of his life. The reality of the death of the speaker’s friend has set in and he finds himself miserable. In a way, the speaker is already giving up the possibility that there can be anything better than the five years he had with his friend. To give up on a full life so early is depressing. Additionally, in Canto 71 the characteristics of depression can clearly be seen. For example, the speaker writes, “Sleep, kinsman thou to death and trance / And madness, thou hast forged at last” (1321-1322). Within these lines, sleep symbolizes not only death, but also a dazed depressed state. This dazed depressed condition leads the speaker into a frenzy of confusion and regret. The speaker believes that sleep and dreams are preferable to wakening life depicting a man too depressed to even get out of