Aaron Banks age 21 has been taking the drug Risperdal since the age 9; even though Risperdal approved for children at the time Aaron was still taking Risperdal. He was still approved to the drug. He grew female breast large enough to be surgically removed. Risperdal is a drug used to treat symptoms of bipolar disorder. Risperdal is also used in autistic children to treat symptoms of irritability. The problem with the Risperdal case is that The Company Johnson and Johnson prescribed a drug that has a health risk. In this case the possible outcomes that may be uncovered are who J&J sold this drug to and what did the FDA do about this situation. Is this drug still on the market to be prescribed to children and adolescents with autism? How many …show more content…
cases of the Risperdal have been identified? How many studies did the pharmacist do on this drug before putting the drug on the market?
The FDA says that they test there medicines on healthy patients but hundreds of people die from simple mistakes like not watching each person side effect and report the correct information in clinical reports. NO criminal charges were faced to Johnson and Johnson and I think some criminal charges or a settlement for patients who experienced the side effects that the drug Risperdal caused. Each year the FDA take 100,000 people lives from taking medicines that are being approved by the FDA. Who is the FDA truly protecting and what responsibilities does the FDA accept due to the fact that more deaths are led by drugs that are approved by the FDA. The FDA say there for the people but are they really thinking about the lives there taking or the money that their gaining from the drugs they approve each year. The FDA is responsible for protecting the public health by ensuring that human and veterinary drug, and vaccines and other biological products and medical devices intended for human use are safe and effective. The FDA should no longer approve medicines that may cause severe side effects or in some cases death; drugs who manufacture these medications should face criminal
charges. According to some of the cases the boys grew breast as large as 38 D cup after using the medications. Johnson and Johnson were accused of paying doctors to speak highly about the drug and to encouraging physicians to prescribe Risperdal to children under age and adolescents. Johnson and Johnson agreed to pay out the settlement for billions of dollars but half of the settlement went to the government and states. Did any of the settlement go to patients who developed female breast? The patients who were endangered by Risperdal did not receive any of the settlement. They also state the wrong doings against patients who took the drug Risperdal. It seems as if it was a scandal going on the promotion for Risperdal has been going on for years. How much money did the pharmaceutical industry gain from this drug? According to Rot-law from 1999 to 2004 Johnson and Johnson paid $50 million to pharmaceutical to supply to companies. The company who Johnson and Johnson paid the money to was the Omnicare. Omnicare was selling Risperdal to elderly in the nursing home. The Omnicare tried to settle their own settlement lawsuit against the government for $122 million. Omnicare the only ones who filed lawsuits cases against J&J. States also filed lawsuits against J&J on the drug Risperdal. The FDA does not approve of this drug for elderly patients but approves of Risperdal for children and adolescents. This is ludicrous because the drug gives off high risk health issues. The FDA approved of Risperdal is used to treat schizophrenia for age groups 13-17 for short-term treatment or for mixed orders for bipolar disorder. This is the same drug that gave boys female breast at an early age. The drug not only gives boys female breast but youths experience weight gain which can cause obesity. “Children treated with anti psychotics are at significantly higher risk for developing type 2 diabetes, obesity, and heart conditions”. (Mindfreedom)In 1996 The FDA rejected the J&J first clinical trial due to the lack of clinical evidence. It’s not Johnson and Johnson first time putting in false information to the FDA about the risk on the drugs. A solution for patients who are taking the drug Risperdal should watch their weight and the effect that the drug is giving off to their body. No criminal charge has been applied to J&J the drug maker company. Criminal charges should be applied because this drug only give boys female breast but can also cause type 2 diabetes and heart conditions that could be avoided by not taking the drug or taking a drug that have harmful side effects. More people die from taking drugs approved by the FDA then they do by being diagnosed with the disease or health issue. Each year 100,000 people die taking drugs that the FDA has approved. Patients who are taking medications approved by the FDA should do more information on the drug that the doctor prescribes. People should start using home remedies for certain illness, but if the illness has a cure that have many side effects. In conclusion The FDA should no longer approve medicines that may cause severe side effects or in some cases death; drugs who manufacture these medications should face criminal charges. The FDA should be careful on clinical trials and report the truth because people are losing their lives from information that could have been simply reported.
As proton pump inhibitors (PPIs) Omeprazole and Lansoprazole are effective therapeutic agents for Peptic ulcers. But which one is more effective as a PPI and highly useful for peptic ulcers disease. The basis of the distinction lies in the pharmacological safety and efficacy of each PPI, which is assessed in this paper in a head to head comparison. After obtaining the relevant literature from Database PubMed and Proquest, it is sufficient to conclude that Lansoprazole proved to be a more effective and safe than Omeprazole.
Mayo Clinic Staff. "Autism." Autism- MayoClinic.com. MayoClinic, 06 Oct 2012. Web. 11 Dec 2013. .
A relatively newer biologic, rituximab provides an alternative strategy for treating the presenting patient. A genetically engineered chimeric anti-CD20 monoclonal antibody, rituximab exerts it therapeutic action by selectively targeting CD-20 positive B-cells1212, 18. As CD-20 is expressed exclusively on pre-B and mature B lymphocytes; stem cells and plasma cells are not implicated in rituximab therapy. The over expression of B-cells expressing the CD-20 surface antigen in the synovium of RA-affected joints has been well established18. The potential mechanisms by which these B-cells contribute to the immunopathogenesis of RA are as follows: they can act as antigen presenting cells, secrete pro-inflammatory cytokines (including tumour necrosis factor-alpha), and generate rheumatoid factor (RF) and other auto-antibodies whilst also activating T cells12. Hence, the rituximab mediated depletion of B-cells is thought to prevent these potential mechanisms from occurring thus controlling the progression of the disease18.
Valium (Diazepam) is an anti anxiety association (benzodiazepine), used basically for transient alleviation of moderate to sensible uneasiness. Data innovation would likely likewise be used to mend signs and manifestations of great fermented drinks drink appropriations, to aid control epilepsy, or to simplicity ligament fits.
The Food and Drug Administration (FDA or USFDA) is a federal agency of the United States Department of Health and Human Services, one of the United States federal executive departments. The FDA is responsible for protecting and promoting public health through the regulation and supervision of food safety, tobacco products, dietary supplements, prescription and over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, animal foods & feed and veterinary products.
There is a great deal of controversy surrounding the issue of children being medicated with powerful psychotropic medications. Psychological disorders, such as bipolar disorder, that were once believed only to effect adults, are now being diagnosed in children, and those children are, more often than not, now being treated with medications. The number of children being diagnosed and treated with psychotropic medications has rapidly increased in recent years. A report issued by Medco Health Solutions in 2010 states that the number of children being prescribed psychotropic medications doubled from 2001 to 2010. Psychotropic medications can be defined as "any medication capable of affecting the mind, emotions, and behavior"(medicine net). The classes of psychotropic medications are; Stimulants, such as Adderall- prescribed for Attention Deficit Hyperactivity Disorder, Antidepressants, such as Prozac- prescribed for depression, Anti-psychotics such as Haldol - prescribed for behavioral disorders, and Mood Stabilizers, such as Depakote - prescribed for bipolar disorders. These medications have been shown to "stunt growth, cause obsessive behaviors, suppress spontaneity, and cause children to become depressed and less social"(Breggin, 2009). This paper will discuss what research suggests about the potentially negative effects of these medications on a child’s physical, cognitive, and socioemotional development. In addition, this paper will also examine the potential reasons these medications are increasingly prescribed, and alternative treatments for some of the psychological disorders that these kinds of medications are prescribed for.
FDAs public health protection duties. By ensuring that products and producers meet certain standards, FDA protects consumers and enables them to know what they are
Drugs used to help mental illnesses; however, they aren’t always the easiest to deal with. With new drugs being discovered each year, they each will have many side-effects that may not be known to the world. Just remember that there are other options when dealing with children with mental illnesses, than medication such as Xanax, Zyprexa, Lexapro, Adderall, and Dexedrine. It may not be best to use the “easy-way-out” when handling a young child with a mental illness. With prescribing medications to children, they may ruin the child’s life, by causing life-changing effects to happen to child’s body. There is no sense of using medications unless it is absolutely necessary, like when the child is sick with the flu or has a sinus infection. Choose another pathway for your child to cope with their mental illness.
The FDA is vital to our country, albeit makes mistakes. Sometimes the FDA can be too
Every year approximately 200,000 souls die from prescription drug reactions, with another 80,000 dying from medical malpractice (The International). Where is the FDA based? Why do they continue to allow doctors to prescribe these drugs? How could they get to this point? What once was believed to be a panacia for depression has turned into Pandora's box (Tracy).
I. The use of alternative medicines for the treatment of autism can be very risky and can cause potential hazards
J.S. was recently started on Methimazole for the treatment of hyperthyroidism. Hyperthyroidism was diagnosed by lab results and thyroid ultrasound. She was prescribed Methimazole 5 mg oral tablet 3 times per day. The current dosing is appropriate for this patient as the recommended initial dosage for mild hyperthyroidism is 5 mg orally every 8 hours. Thyroid hormones are produced and released by the thyroid gland and regulate the body's metabolism. Methimazole is an antithyroid agent. The mechanism of action involves inhibition of thyroid hormone production. Inhibition of thyroid hormone production normalizes the thyroid gland and reduces the symptoms of hyperthyroidism.
Federal Drug Administration (FDA) bans foods and drugs. The Federal Drug Administration bans things that may be a nuisance to the society. Items that may cause choking hazards or products that come from overseas that may be harmful are banned. Items that are banned may not have a good enough reason to be banned, this may cause certain people to be frustrated and angry. Although not banning items may cause commotion in some ways, it is acceptable to see what the product does to the country because the product may do good for certain people.
Revco Drug store was a rated in 1956 and it raised into debt from a company purchase of Odd Lot Trading Co. To expand the company, Revco needs drug selling services, by inquiring many of its competitors. Revco retail slowly started to decline. Towards the final stage, the company was headed in debt. After continued borrowing, the company had a debt of 1.7 billion US dollars.
Pharmacovigilance is defined as study and surveillance of post marketed drugs. The importance of pharmacovigilance is to ensure the safety of drugs consumed by patients. So, why U.S. Food and Administration (FDA) still surveillance post marketed drug even though, these drugs go through such vigorous review, follow strict procedures and standards that are in compliance with GMP established by FDA during clinical trials and also goes through CDER. The Center of Drug Evaluation and Research (CDER) is a part of FDA that is responsible for the safety and effectiveness of all drugs ranging from prescription drugs to over-the-counter, which includes; shampoo, deodorant, sunscreens, vitamins etc. The way the research and investigation at CDER works is that, there are different departments for types of products. For example; generic drug, clinical review, biotechnology products or therapeutics products. Not only, CDER is responsible for safety and effectiveness of the drugs but they also provide information on how to use the drugs safely and effectively for both healthcare professional and co...