Prozac At first it was the cure all people were looking for. Then it became the drug they were afraid to take. Somewhere between these two extremes lies the truth about the drug Flouxetine, better known as Prozac, the most widely prescribed drug on the globe. It is mainly prescribed to patients suffering from clinical depression. It was first brought to the market in 1988 by the pharmaceutical giant Eli Lilly co. Even though it was originally prescribed for depression, it has been prescribed for everything from eating disorders to insomnia. It was first considered the wonder drug of the new decade because of the way it helped depression patients when no other anti-depressant could and then also found to help many other personality disorders as well. But now it is frowned upon by many. Some of the side effects contributed to the growing opposition of Prozac include nausea, constipation, memory impairment, and excess sweating, just to name a few. What is depression? Depression can result from a physical disease, a mental illness, or it can be a recurring reaction of the body. According to the National Institute of Mental Health, major depressive illnesses are often the result of imbalances in neurotransmitters in the brain. It is these critical chemicals that send messages between nerve fibers and control mood (Creamer, 3). Older anti-depressants worked on three different neurotransmitters, serotonin, norepinepherine, and dopamine. However, it has been found that serotonin is the specific chemical in the brain that controls moods. Its job is to carry an impulse from one nerve fiber to the next. Serotonin is released by the nerve into the space between nerve fib... ... middle of paper ... ...fects, but everyone still takes these medications. Why, because they work. No one can argue that Prozac is working for many people, considering that it is the most prescribed drug in the world. But if it is not right for you, then you need to find what is good for you, not everyone can take every kind of medicine. Some people have allergies, that's going to happen. The bottom line is, it is difficult to argue with clear results. Works Cited Aprile, Diane. "Prozac." Courier-Journal. Feb. 18, 1990. Bihm, Barbara; Wilson, Billie Ann. "Understanding Fluoxetine (Prozac)." Medsurg Nursing. Feb. 1, 1996. Creamer, Beverly. "Prozac: Its Effects Still Subject to Debate." Honolulu Advertiser. May 30, 1993. Mauro, James; Breggin, Peter. "And Prozac for All..." Psychology Today. July 1,1994. Nichols, Mark. "Questioning Prozac." Maclean's. May 23, 1994: 36-41
Treating depressive and bipolar disorders with antidepressants remains a popular option in clinical practice. Most clinicians choose the drug or class of drugs, usually selective serotonin reuptake inhibitors, SSRI's, that is most effective and best tolerated with fewer severe side effects. These drugs are beneficial because they specifically target serotonin-based areas of the brain without affecting other neurotransmitter systems. SSRI's largely replaced tricyclic antidepressants which work by blocking the absorption (reuptake) of the neurotransmitters serotonin and norepinephrine, thereby increasing the levels of these two neurotransmitters in the brain. Tricyclic antidepressants present severe side effects and thus are usually only used when other treatments have failed. If SSRI's or tricyclics are not effective Monoamine oxidase inhibitors may be prescribed. MAOI's, enhance tyramine to increase norepinephrine and serotonin. While taking MAOI's you must abstain from foods and alcohol that contain tyramine such as, yogurt, aged cheese, and substances such as cold medications. This is because a potential toxic reaction could occur. Additionally, other antidepressants may be utilized such as Wellbutrin (bupropion) an NDRI-
The use of psychotropic medication in children and adolescents dates back to 1937 when Charles Bradley conducted a study by prescribing the stimulant amphetamine sulphate (Benzedrine) to modify the behavior of children with severe behavioral disturbance. (Adams, 1991) Since these studies were conducted, more and more children and adolescents have been prescribed stimulants, antidepressants, antipsychotics, and mood stabilizers for various mental disorders, such as: depression, bipolar disorder, schizophrenia, anxiety disorders, and attention deficit-hyperactivity disorder (ADHD). The potential side effects that happen to children taking these medications can include: fainting, blurred vision, vomiting, extreme weight gain, and even death ("Seroquel information,” n.d.).
Antidepressants are usually a type of drug called SSRIs. SSRI stands for selective serotonin reuptake inhibitors. The most popular antidepressants such as Zoloft, Paxil, Celexa, Lexapro and Luvox are all SSRIs (Antidepressant Medications for Children and Adolescents). Many newer antidepressants are SSRIs due to less side effects and more safe for adults compared to other older generations of antidepressants. Children and teens on the other hand are not. In fact, the FDA put a black box warning on SSRIs which “is the most serious type of warning in prescription drug labeling” ( Antidepressant Medications for Children and Adolescents). There’s actually only one SSRI that can be prescribed for depressed children (who must be eight and older) which is Prozac and That hasn’t prevented SSRIs ...
LSD stands for Iysergic acid diethylamide. LSD is a hallucinate know to be the most powerful drug of this kind. LSD is commonly known as acid. This drug changes a person’s mental state by distorting the perception of reality to the point where at high doses hallucination occurs. Acid is derived from a fungus that grows on rye and other grains. It is semi-synthetic. It’s manufactured chemically in illicit laboratories, except for a small percent, which is produced legally for research.
Through my extensive research on depression I have learned a lot of new things. I have learned about the many forms of depression and treatment for depression. I have also learned a little about what is believed to go on chemically in the brain of a clinically depressed person. I was also able to partially determine what sort of role genetics, chemicals and personal influences in the brain. Though I was unable to determine exactly how environmental and personal stress can cause a chemical imbalance in a person, I was even able to speculate about this issue and determine some theories of my own on why and how this may happen.
Antidepressant are a form of pharmacotherapy treatment developed to treat the symptoms of major depression. Antidepressants are used for many other types of conditions including anxiety disorders, obsessive compulsive disorder, dysthymia, eating disorders, sleeping disorders, and substance abuse, pain syndromes, gastrointestional disorders. Antidepressants usually require several weeks to notice significant effects. There are no antidepressants or any medication that is completely free of adverse effects. This article explains that the adverse effects of antidepressant can decrease compliance and slow down the rate of recovery. It is important for one to take note of potential side-effects before choosing the best antidepressant to suit their personalized needs. Statistics show that about 28 percent of patients sto...
Serotonin is a "neurotransmitter which is responsible for mood, hunger sleep" (www.herbsnow.com/sotm.htm). The website, medquest pharmacy claims that 5-HTP works by increasing the amount of serotonin produced in the brain. And in fact, according to Gastpar and Wakelin (1998), 5-HTP is a known precursor to serotonin which has been proven in many studies. Serotonin levels are supposed to have a direct effect on a persons mood (www.medquwestpharmacy.com/5-htp.htm). In fact antidepressant drugs approved by the FDA, such as Prozac, are said to work by increasing the amount of serotonin available to the brain(www.biosyenrgy.com/5htp.htm).
Depression does not have a lone cause. An individual gene cannot handle mood or spur up depression. However, genes can influence the way nerve pathways perform. Multiple genes cooperate to evolve a susceptibility to depression. In addition to the biological aspect of depression, neurotransmitters and hormones are chemicals that allow nerve cells to communicate. Not only do they control mood and emotions, but the way these chemicals are broken down may add to the growth of
The biologic basis of Clinical Depression originates in the brain. Your brain is made up of a complex network of nerve cells, called neurons and of brain chemicals, called neurotransmitters. Neurotransmitters transmit messages from one neuron to another. Two of these neurotransmitters are not produced in sufficient quantities in a depressed person’s brain. Because of this lack, too few messages get transmitted between neurons and the symptoms of depression occur. In Clinical depression the chemicals in the brain are out-of-balance. New technology allows researchers to take pictures of the brain that show activity levels in the brain. These imaging techniques such as f-MRI and PET scan actually create images of how active different parts of the brain are. Some studies with these kinds of techniques have suggested that the patterns of activation in the brains of depressed people are different than those who are not. These tests can help doctors and researchers learn more about depression and other mental illnesses. Since this research is fairly new, it is not yet used to diagnose clinical depression.
In a statement on April 2, 2010, pilots can start applying for air duty starting April 5th. Contingencies include the pilots have to be stable on the medication for the previous twelve months and the FAA will not punish pilots who have been using antidepressants secretly if they disclose such information in the next six months. Each pilot taking the drugs will have to be examined once every six months by an aviation medical examiner. The FAA states that this regulation is in line with many other flying organizations and is supported by the pilot's union. The Wall Street Journal states that a ban on psychiatric drugs stems from side effects such as drowsiness and sedation but the four drugs being used have far fewer side effects. The public has an opportunity to comment on the changes until May 3, 2010. Rationale The reasons for the move are twofold. The first is that the FAA wants to remove the stigma attached with depression in pilots. The general population has about a ten percent rate of usage for antidepressants and the FAA assumes pilots do not have a higher rate. The problem with this is that some pilots admittedly have been taking antidepressants in secret and may not be forthcoming with their usage. Another reason for the changes is that there should be no secrecy or stigma if a pilot has depression. Each case will
Depression is a mental illness, which affects millions of Americans each year. Currently there are many prescription drugs, called anti-depressants that have been proven to successfully treat it. The causes of depression are somewhat of a medical enigma, however, it is known that depression is associated with a change in the brains chemistry involving the function of neurotransmitters (Reichert). This chemical change occurs in healthy brain’s, which experience sadness, but ends after the unpleasant stimulus is removed. In people suffering from depression this chemical change does not correspond to any particular stimulus. Symptoms of depression are often incapacitating and include severe and extended sadness, feelings of worthlessness, feelings of emptiness, irritability and anxiety (Reichert, Spake).
"If the human brain were simple enough for us to understand, we would be too simple to understand it" (1).
In fact, Prozac?s manufacturer admits that 35% of all patients receiving Prozac in pre-release trials stopped taking it due to adverse reactions. A vast personality change is another effect. Some users reported that after being on Zoloft for two months (which is the time it takes for their bodies to become chemically dependent) one day without their pill would make them more on edge, more reluctant to?snap? at people and more sensitive to others' remarks. The depressed patients also reported feeling dependent on the drug and without it, they felt they would not be able to function how the normal would.