Necrotizing Enterocolitis Case Study

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Necrotizing Enterocolitis (NEC)

By Jonas Wilson, Ing. Med.

Necrotizing enterocolitis (NEC) is a life-threatening condition that manifests as inflammation of the intestines. This devastating disease affects mostly premature babies, who account for up to 8 out of every 10 cases. In NEC, bacteria invade the intestinal wall and the local infection and inflammation lead to destruction of the intestinal lining and/ or its entire thickness. A breach in the integrity of the bowel wall enables bacteria to escape into the abdominal cavity. By this means, the bacteria cause a massive infection, which has the ability to progress quickly and may lead to death if not treated immediately. Hence, NEC is a medical emergency.

Patients typically present with swelling or bloating and poor feeding tolerance. Moreover, they may experience vomiting, blood in the stool, lethargy, apnea and fever. These signs and symptoms usually develop within the first 2 weeks of life. Diagnosis is made with the help of physical examination and abdominal X-rays, which may show the presence of air in the abdominal cavity. Treatment may vary depending on disease extent and the overall health of the infant, but includes antibiotic therapy, IV-feeding and in serious cases breathing support and surgery.

Epidemiology …show more content…

This frequency is suggested to be similar in other countries, but may be lower in countries with lower rates of premature births. NEC is more commonly seen in premature babies. The prevalence of NEC is equal between male and female babies and the incidence is inversely proportional to the gestational age and birth weight. The highest rates of NEC are seen in infants born with a weight at birth less than 1 kg. Infants born with a weight between 1.5 – 2.5 kg and those who are born after 36 weeks of gestation have significantly lower chances of developing

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