Mukherjee's Mitochondrial Eve Theory

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I do not associate myself with any traditional religion, but sometimes when I discover some historical or scientific anomaly I stop to wonder at the beauty of the universe. Recently, while reading The Gene by Siddhartha Mukherjee, I stumbled upon the idea of ‘Mitochondrial Eve’. This is a theory—the term Mitochondrial Eve refers to a person—that all humans alive today have one common great great great great… …great grandmother. I had heard this idea before but had not understood how mystically intriguing the basis of the theory is. Mitochondria, the powerplants of eukaryotic cells, originated (according to current understanding) from the symbiosis of an early eukaryotic precursor and a specialized energy-producing bacterium. Thus, each mitochondrion has its own genome separate from the nucleus of its “host” cell. Mitochondrial DNA is often used to determine human origins because it is not subject to the recombination that affects the 23 chromosomes in the nucleus—mitochondrial genomes are an untampered historic record of every single mutation in human …show more content…

The formation of a gamete occurs when a sperm injects its DNA into an egg cell. Only its nuclear DNA. Sperm do not transfer any organelles or nutrients to the egg. This means that all of that gamete’s organelles and cytoplasm come exclusively from the mother. This includes the mitochondrion and its genome.
If mitochondrial DNA is only passed down from the mother, and mitochondrial DNA paints the most accurate picture of evolutionary history, then every human can be traced back to a single female ancestor. Males cannot pass on this DNA, so with each generation, assuming a 1:1 ratio of male to female offspring, only half of a population’s females have given rise to the potential to pass on their mitochondrial DNA on to future generations (i.e.. Only half of the females gave birth to a female child). Every male child is a dead end for mitochondrial

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