Migraines: Episodic Disorders

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Migraines are one of the most common, episodic disorders, in which the patient experiences a severe headache that may also accompany with nausea, and/or light and sound sensitivity. Migraine pain can be mild to severe in intensity and can last four to seventy hours (Buttaro, Trybulski, Bailey, and, Sandberg-Cook, 2013). It usually has a preliminary period in which patients can experience tiredness, decreased concentration, irritability, and noticeable yawning. Warning signs like these may occur several hours or even days before the full onset of the migraine episode (Sprenger and Goadsby, 2009). Patients can experience a migraine with or without aura. The aura is described as a visual disturbance where a patient sees shimmering bright light, …show more content…

The patient must also have one of the following criteria: Visual or audio sensitivity, nausea, and vomiting. For the criteria for the patient who has migraines with aura they have to have even more specific criteria in addition to the criteria mentioned previously (Edmunds and Mayhew, …show more content…

One theory suggests that migraines are manifested by a phenomenon called cortical spreading depression (CSD). The patient may experience an aura prior to the start of migraine pain. CSD is described as a local disturbance of the brain function that is characterized by a temporary, local suppression of the spontaneous electrical activity in the cortex that spreads over this region of the brain, and appears to be the symptom of CSD (Sprenger and Goadsby, 2009).
Another theory, called dura plasma protein extravasation, suggests that plasma proteins in in the brain, specifically the dura, leak out and cause migraine pain. Along with this, there is also excessive trigeminal nerve stimulation and is one function of an approaching migraine episode. Sumatriptan, is a medication that can effectively actually inhibit this process, and unfortunately it was discovered that this was not successful in controlling the pain. Because of this, this theory doesn’t help solve what the actual mechanism of migraine headache symptoms really are (Sprenger and Goadsby,

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