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Research paper about phenylketonuria
Research paper about phenylketonuria
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Human skin contains about the same number of melanocytes for each individual. Melanocytes are found in the epidermis of the skin. It is possible for every skin color to have a similar number of melanocytes because melanocytes produce a substance called melanin. Melanin breaks down into two substances called eumelanin and pheomelanin. Eumelanin is what controls how dark your skin will be. The more eumelanin the darker your skin. Genetics is what will determine how much and what kind of pigment you will have. One of the genes related to your skin color is melanocortin 1 receptor, also known as MC1R. When your MC1R is healthy it helps melanocytes convert pheomelanin into eumelanin. If your MC1R is not healthy this will cause a buildup of pheomelanin. If someone has red hair or very …show more content…
fair skin there is a good chance that they have a type of MC1R that does not work properly. Another indication of the color of your skin is the amount of sunlight you are exposed to.
Our skin receives ultraviolet rays from the sun. The measure of ultraviolet light rays your skin actually absorbs can be very detrimental to you. Ultraviolet rights can dismantle your folic acid or cause changes in the DNA. These are some ways people can obtain skin cancer. In response to the sun our skin produces Vitamin D. The more eumelanin you have, or the darker your skin, the harder it is for you to make Vitamin D because melanin tends to act as a filter. This means that darker complexions will need be exposed to more sunlight in order to obtain a great deal of Vitamin D. When people are exposed to ultraviolet for an extensive period of time this can cause skin wrinkles. Wrinkles are a sign of lost elasticity in the dermis. The alteration of elastic fibers is what causes the skin to lose its elastic property. A couple other disorders related to the integumentary system include Rosacea and Tinea. Rosacea can be diagnosed by its red appearance around the nose and cheeks. It also looks similar to a rash. A physician would be able to diagnose Rosacea by the fine network of dilated blood
vessels. Rosacea also can also progressively get worse when people drink hot drinks, alcohol, or eat spicy food. This disorder can accurately be diagnosed because it typically begins between the ages of thirty and fifty. There are no specific test to diagnose Rosacea but there are test to rule out other possible disorders. Another disorder of the integumentary system is Tinea. Tinea, on the other hand, is a fungal infection. It is most known for its name “ringworm” because of its circular growth pattern. Tinea is prominent in moist areas such as your armpit, foot, or groin. Tinea tends to be red and itchy and have raised patches. These patches can sometimes ooze or be red on the outside edges. Tinea can be diagnosed easily by a physician by just observing the affected area. If unsure a doctor could take a skin biopsy which would send a sample of your skin or discharge to a lab for testing.
Anthropologists and geographers have studied and overtime come to the conclusion that distribution of skin color is not random. Darker skin color has been found to typically come from near the equator and lighter skin colors are typically coming from closer to the north and south poles. Over the years, researchers have found that darker skin colors has protected the skin from having skin cancer. Recent studies have shown that “skin color is the product of natural selection acting to regulate the effects of the sun’s ultraviolet radiation on key nutrients crucial to the reproductive success” (169).
The hair of the scalp is longer and more flexible, while the hair of the eyebrows tends to be short and stiff. Oval shaped hair shafts produce wavy hair, flat hair shafts create curly hair and hair shafts that are perfectly round create straight hair. There are also different types of melanin, a natural compound responsible for the production of color in the eyes, skin and hair. There is yellow, brown and black melanin, each produced by melanocytes located at the follicle base. With age, melanin production decreases, causing greying of hair. (Applegate & Saunders, 2001, pp
Tanning is a commonly used by Caucasian women to cause their skin tone to darken. Melanin is what gives skin its color. Naturally, when we are exposed to sun, the production of a pigment known as melanin starts which itself acts as a deterrent to the burning effects of ultra violet rays of sun (Pakhare). Some Caucasians find it necessary to tan to increase beauty. It is not necessary to tan to increase beauty.
Tanning affects the human skin through ultraviolet radiation, part of the spectrum of light that omits from the sun to the surface of the earth. Ultraviolet A rays are the longer ultraviolet rays that are projected, and these rays penetrate deep into the layers of skin, causing a tanning effect (Harvard Women's Health Watch, 2). It does this by penetrating into the lower layers of skin, or the epidermis, and triggering cells known as melanocytes to make melanin, the brown pigment that causes tanning (Hyde, Patrice, MD, 1). They account for most of the ultraviolet components emitted by lamps in tanning beds, because they are associated with an almost immediate tanning effect (Brady, Mary S, 2). The shorter rays are ultraviolet B rays, and these rays only reach the outer superficial skin cell layer, also known as the epidermis (Harvard Women's Health Watch, 2). UVB rays, therefore, are the actual cause of sunbur...
There are two common misconceptions about melanoma. The first is that melanomas develop only in sun-exposed areas of the body. In fact, melanomas can occur in areas not normally exposed to the sun, including the abdomen, genitals, and soles of the feet. The second misconception is that dark-skinned and Asian people are not at risk for the disease. In fact, one type of melanoma occurs most frequently in African American and Asian populations, developing on the palms, soles, and nail beds.
Melanin helps reduce the absorption of wavelengths into the skin (Chaplin, Jablonski, 59). The more melanin in the skin, the greater the protection against harmful UV rays, and the amount of melanin in the skin correlates with the skin’s color (more melanin means darker skin)....
Human pigmentation is influenced by hemoglobins within blood vessels in the skin, carotene and melanins. Melanin, the basis of pigmentation, can be found in the forms of eumelanin and phaeomelanin. Eumelanin is the brown-black pigment located in the skin, hair, and eyes. Phaeomelanin is a yellow to reddish-brown pigment found in small quantities within the skin, eyes, and red hair. Because of these two pigments, to a greater or lesser degree, we have the variation in human pigmentation that is seen today.
UV radiation causes significant damage to human skin, in the form of sunburns, aging, skin cancer, and nonmelanoma tumors. Human skin damage is primarily a result of tanning. The
Skin Cancer is caused by hereditary factors, overexposure to the sun, and weak immune systems. (“Skin Cancer” infotrac.com) One reason people tend to get skin cancer is when someone in your family has passed their genes down to you, known as hereditary. Normally hereditary is one of the causes in the development of melanoma. For all types of skin cancers, overexposure of the skin to UV radiation in sunlight is the most frequently blamed source of skin cancer. “Research suggests that sunburns received early in one’s childhood can lead to skin cancer later in life” (“Skin Cancer” infotrac.com). For example, when someone gets sunburned, you usually don’t know till ten to twenty years after and that’s why people don’t get skin cancer till they reach their twenties.
Our vertebrate integumentary system performs many functions within the various layers and tissues of the skin. These tasks help protect the skin from all sorts of dangers. One such thing our skin protects us from is ultraviolet radiation. Our skin, when exposed to sunlight for long periods of time, can change its coloring. This process is what happens when an individual gets tan or sunburned. Melanin a unique pigment that darkens our skin when exposed to sunlight protects our skin from radiation that is found in these ultraviolet rays. It surrounds the nucleus acting as a barrier that protects our DNA from ultraviolet radiation that could cause cancer or DNA complications. Another function that the integumentary system performs is thermoregulation
The color of your skin used to depend on where you live. (Before transportation became so easy.) Darker skinned people would live where it is hotter, and the sun shines more. Lighter skinned people would live in cooler, less sunny areas. This is because the darker pigments in your skin would keep you from burning.
Spencer Wells, known for his book “Journey of Man” is on the hunt for the migration of early humans, and our traits such as race or color come from. Wells states that human life started in Africa; where the sun is strong, humans started off with dark skin for protection. When humans started to move north where there is less sun directivity our skin needed to become lighter to better absorb the sunlight, in order to produce vitamin D. as for the humans that stayed in places with a great amount of sunlight their skin needed to remain dark, so they could absorb just the right amount of sunlight, and this can also be known as the balancing act. Our skin colors vary to adapt, but we are all constructed the same way. We are all humans cultures may separate us, but not color. Geography did not intend to start the inequality of
Vitiligo is a skin disorder in which the skin has a deficiency of melanocytes in some areas, primarily around openings like the nose and mouth and areas with more bone prominences like the knees and elbows; however researchers have not yet discovered why this is, but currently the two most popular and widely accepted hypotheses are genetic and autoimmune causation. Vitiligo has also been noted to be be triggered, or impaired by psychological stress, hormonal changes like puberty and childbirth, trauma to the skin, and even exposure to certain chemicals. There are two main forms of vitiligo: nonsegmental vitiligo, and segmental vitiligo.
G protein-coupled receptors (GPCRs) are the largest class of transmembrane receptors, and collectively they respond to diverse stimuli to regulate nearly all physiological processes. Consequently, GPCRs are considered attractive drug targets, and drugs with agonistic, antagonistic, and modulating properties at GPCRs have been developed to prevent or treat numerous diseases and disease symptoms. Over the past decade, technical advances in the fields of pharmacology, physiology, and structural biology have yielded new insights into GPCR signaling and structure-function, including the first x-ray crystal structure of a GPCR, the 2-adrenergic receptor, in 2007. These insights have challenged canonical models of GPCR ligand-receptor interactions
Probably the most commonly used word by your dermatologist, your beautician, your pharmacist or just the girl next door, and for a good reason. The sun’s damaging UV rays can single-handedly destroy your skin over time and in some cases even cause irreparable damage. It will burn your skin, dry it out, destroy collagen fibers and predispose you to cancer. Whether it’s a scorching sun or not, whether you are outdoors or not, sunscreen is an everyday must-wear. You have a choice.