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Autoimmune hypothyroidism case studies
Notes of thyroid gland
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A butterfly inside the base of your neck, with 2 wings laying each side of your windpipe. Right. That’s how your thyroid gland closely looks like. Although pretty small, yet, it virtually takes a mighty and most significant role in your body and influences the functions of the lifeline organs including the heart, brain, kidneys, liver and skin. When the thyroid gland functions properly and secretes the thyroid hormones as per the body’s demand, you are vitally healthy. When things go wrong and your thyroid gland doesn’t produce the required hormones, then it would slow down all your body functions. This condition is called HYPOTHYROIDISM. It’s the most common type of thyroid disease.
WHAT IT DOES?
Shortage of sufficient thyroid hormones
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Thyroid disease is as common as diabetes and heart disease. Anyone can develop Hypothyroidism right from infants to adults. Preventing your body from under producing thyroid is unfortunately a hardly ever phenomenon.
WHAT ARE THE SIGNS & SYMPTOMS?
The symptoms of hypothyroidism may become visible gradually over a period of time, months or years and sometimes these signs and symptoms can be so simple that you may not even make out that something is wrong and it’s easy to neglect.
As hypothyroidism comes with wide range of symptoms, the recommended way for you is to go for a blood test under a doctor’s opinion to measure the hormone levels and to diagnose the condition.
Common symptoms are:
• Muscle & Joint aches
•
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HOW DO YOU DIAGNOSE?
The diagnosis is commonly made through blood test that measures the level of TSH (Thyroid Stimulating Hormone) and Thyroxine (T4 - thyroid hormone). A low level of thyroxine and high level of TSH indicates underactive thyroid. It shows that your Pituitary gland (located at the base of the brain and responsible for TSH production) produces more TSH in an attempt to stimulate your thyroid gland to churn out more thyroid hormones.
WHAT CAUSES HYPOTHYOIDISM?
The most common cause of hypothyroidism is Hashimoto’s thyroiditis which is an autoimmune disorder. Hashimoto’s makes your body to produce antibodies that attack and damage your thyroid gland. There are also many other variety of factors that causes under active thyroid which includes:
• If anyone in your family is with a thyroid problem
• Damaged pituitary gland
• Down’s Syndrome
• Turner’s Syndrome
• Radiation therapy in the neck area while treating
There is a lot to talk about Armand character in the short story of Desiree’s baby. In the beginning of the story, he is such a great person he loves Desiree. This quote “beautiful and gentle” shows that Armand is fall in love with her. However, his character change, when he found out that baby wasn’t white. His character of being a good husband to a cruel husband. The story clearly explains his initial character and final character. I believe he is not pitiable at all because he shows his cruelty character toward Desiree and not only that, he cares about his social standing, which motivates him. When he bought “fine clothing and layettle” this shows a symbolic object of wealth and his possession of Desiree. He wouldn’t act in a cruel way if
First I will be discussing about the thyroid gland, so the thyroid gland is a gland in the neck that secretes hormones. These hormones regulate growth and development, and metabolism. The main hormone secreted is Thyroxine. So when a person like Margie is diagnosed with hypothyroidism it means the thyroid gland does not secrete enough hormones. As many females get over the age of 50, they are more at risk of developing hypothyroidism. The symptoms
Thyroid and metabolism hormones play a large role in the daily lives of all living species. Thyroid hormones regulate the metabolism and the metabolism is responsible for maintaining a specific range for the biochemical reactions that occur in the body (Martini 2014). The most important hormone for metabolic maintenance is thyroxine (T4). This hormone also plays a large role in body heat regulation. It is produced by the pituitary gland and secreted by the thyroid gland. The thyroid releasing hormone (TRH) must trigger the thyroid stimulating hormones (TSH) to release thyroid hormones to the thyroid gland. These hormones are under control of the hypothalamus, or main neural control center. Propylthiouracil (PTU) is a medication used to treat
As you know autoimmune diseases are your immune auto-generate antibodies against cells of your body. In here, I don’t tell physiology of autoimmune diseases but I will tell one of most autoimmune diseases that is immune fertility disease. Researchers at the University of Virginia Health System have found a new human protein, radical radial spoke protein 44 (RSP44) in July, 2007. RSP44 is antigen can be found in all men, residing in the sperm tail at the center of a structure known as the axoneme. Antigens can only stimulate antibody production when they come in contact with components of the blood. Under normal conditions, blood and sperm do not mix. Direct contact between the two is prevented by a cellular structure in the testes called
Graves’ disease is an autoimmune disease that was discovered by Robert Graves in 1835. Graves’ disease is an autoimmune disease in which the body's immune system attacks the thyroid gland and causes hyperthyroidism. Graves’ disease occurs when the antibodies like thyroid-stimulating immunoglobulin and thyrotropin receptor antibodies (TRAbs) attack the thyroid gland as if it were a foreign object or a virus of some sort. This disease is the most common type of hyperthyroidism. Attacking the thyroid gland in such a manner makes it excessively overproduce the hormone thyroxine which controls the body’s metabolic rate. Heightened activity of the thyroid can increase the body’s metabolism by 60% to 100%. (Weeks 34-35).
Today in America thyroid disease is becoming a much larger issue and the worse part of this problem is that many people are not yet diagnosed. This is due to the lack of education and awareness about thyroid disease. There are many different types of diseases but the one that I am passionate about is hypothyroidism. Hypothyroidism, or underactive thyroid is when the thyroid is no longer able to produce triiodothyronine, also known as T3 and thyroxine, also referred to as T4. Some of the symptoms include unexpected weight gain, tiredness, depression, or slow movements and thoughts. Most of the time many people notice the way that their bodies act on what they are feeling to their physicians. Many Americans struggle with this disease that
Hypothyroidism is a chronic disease that is part of the endocrine system. Hypothyroidism is due low or lack of tri-iodothryonine (T3) and tetraiodothyronine (T4) thyroid hormones being produced by the thyroid gland. The lack of thyroid hormones could be due to iodine or thyroid stimulating hormone (TSH) deficiency or underactive thyroid gland (Sherwood, 2012). Thyroid hormones T3 and T4 are involved in almost every part of the body. It is ten times more prevalent in female than male, which affects about 4.6% of U.S population (Lellis-Santos et al, 2011). In the most cases, the symptoms are cold intolerance, fatigue, bradycardia and weight gain. Depending on the cause on hypothyroidism, a goiter may develop, which is the enlargement of the thyroid gland. In most cases taking thyroid hormone supplement is an effective treatment.
The balance of the thyroid hormone is complicated and involves the participation of different parts of the body (Kaplustin, 2010).
The thyroid gland plays a major role in the endocrine, thyroxine, triiodothyronine and metabolism system. The gland can be found in the front of the neck and above where the collar bones meet. The thyroid gland controls the body by releasing T4 and T3 hormones. Controlling metabolism plays an important role when regulating mood, weight,
The thyroid gland is found in the front of the neck and produces two main hormones. The hormones are called thuroxine (T4) and Triiodothyronine (T3). Together these hormones regulate the body’s metabolism by increasing energy use in cells, regulate growth and development, help to maintain body temperature and aid in oxygen consumption. These two hormones are regulated by hormones produced by the hypothalamus and pituitary gland. The hypothalamus senses changes in body’s metabolic rate and releases a hormone known as thyropin-releasing hormone (TRH). This hormone then flows through connecting vessels to the pituitary gland which signals it to release another hormone. This hormone is known as thyroid-stimulating hormone (TSH). TSH then makes its way to the bloodstream until it reaches the thyroid where it is then signaled to activate T3 and T4 production [1]. This mechanism is controlled by a negative feedback loop meaning that when there is a sufficient amount of thyroid hormones in the blood stream, this will signal back to stop production of thyroid stimulating hormones. Complications occur when the thyroid hormones keep increasing even though there is already a sufficient amount of T3 and T4 in the blood stream. This process of over expression of thryroid hormones is known as hyperthyroidism. Hyperthyroidism is a general term that includes any disease that has a consequence of an overabundance of thyroid hormones. Hyperthyroidism is a general term but there are many variant diseases that are in the hyperthyroidism category. These diseases include diffuse toxic goiter, Basedow’s disease, thyrotoxicosis, Parry’s and Graves’ disease.
(Main Point 3) After a long period of time, high blood sugar levels can have a serious effect on all the body's organs.
Among these disorders are hypothyroidism and hyperthyroidism. Hypothyroidism is a disorder in which one is diagnosed for having and underactive thyroid. The probability for women over the age of sixty to develop an underactive thyroid is higher than those of other individuals. If left untreated it can potentially lead to obesity, joint pain, heart disease, and other health complications. On the contrary, hyperthyroidism is a disorder in which a person is diagnosed for having an overactive thyroid. This can cause nervousness and anxiety, hyperactivity, unexplained weight loss, and swelling of the thyroid gland which causes a noticeable lump to form on throat (known as a
Thyroid cancer has a multitude of symptoms that one can use to idenfity it. For example, a lump on your neck, pain in the throat or neck, difficulty swallowing, and swollen lymph nodes are all examples
There are multiple causes for hyperthyroidism. According to the Merriam Webster website, hyperthyroidism means excessive functional activity of the thyroid gland; also resulting condition marked especially by increased metabolic rate, enlargement of thyroid gland, rapid heart rate and blood pressure. Thyroid gland is a part of the endocrine system and is located right below the Adams apple. The endocrine system is very important to the human body. The function of the endocrine system is to coordinate and integrate cellular activity within the whole body by regulating cellular and organ function throughout life and maintaining homeostasis. Homeostasis, or the maintenance of a constant internal environment, is critical to ensuring appropriate cellular function. For example, maintaining body temperature, weight management and heart rate. However, when the homeostasis of the internal environment isn’t maintained, pathologies associated with hyperthyroidism can develop. There are multiple diseases associated with hyperthyroidism, Graves’ disease, excessive intake of iodine and mulitnodular goiter. The function of the endocrine gland is to secrete hormones in the internal body. For example, thyrotropin-releasing hormone is released by the hypothalamus to the anterior pituitary gland, which releases thyroid-stimulating hormone (TSH) and binds to TSH receptors on thyroid gland. This leads to the production of triiodothyronine (T3); thyroxine (T4). Certain pathologies increase the production of T3 and T4 leads to hyperthyroidism. Hyperthyroidism is also known as overactive thyroid is caused by excessive production of T4 and T3 in the thyroid gland. This will significantly lead to changes in the internal homeostasis causing sudden weight ...