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Hypothyroidism essays
Hypothyroidism essays
Hypothyroidism lecture note
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My case study was based on a women name Margie. Margie is a 50 year-old women that frequently exercises and maintains a healthy eating habit. Even though Margie is a fit 50 year-old her cholesterol was well above average 222. Her trainer then recommended her to sign up for extra kickboxing class and maintain a vegetarian low fat diet, therefore her cholesterol would decease. About a month later she tested her cholesterol again and after the extra exercise, low fat diet her cholesterol was higher than the previous time at 230. Therefore, Margie attended the doctor where she was diagnosed with hypothyroidism.
First I will be discussing about the thyroid gland, so the thyroid gland is a gland in the neck that secretes hormones. These hormones regulate growth and development, and metabolism. The main hormone secreted is Thyroxine. So when a person like Margie is diagnosed with hypothyroidism it means the thyroid gland does not secrete enough hormones. As many females get over the age of 50, they are more at risk of developing hypothyroidism. The symptoms
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that come along with hypothyroidism are being fatigue, weakness, weight gain, hair loss, sensitivity to cold, muscle cramps and aches, constipation depression, and abnormal menstrual cycles. Before Margie was diagnosed with hypothyroidism her labs indicated she had a high cholesterol value along with high (LDL) low-density lipoprotein. Her high-density lipoprotein (HDL) and (TSH) thyroid-stimulating hormone were high as well. Only her free T4 was low. All these value lead doctor to hypothyroidism diagnoses. Is still unknown why hypothyroidism is associated with elevated LDL cholesterol. The type of Margie’s hypothyroidism was Primary hypothyroidism, which is an autoimmune disease.
Is consider an autoimmune disorder, because elevated enzyme (TPO) Thyroid Peroxidase which are thyroid follicle cells iodinates T4 and T3. TPO ends up attacking it self, resulting in inflammation which ends up damaging the thyroid gland. Primary hypothyroidism is also known Hashimoto disease. The primary hypothyroidism lead to Margie’s symptoms trouble concentrating, puffier face, and hot flashes. Considering all the things above, Margie will be treated with Levonthyroxine a thyroid replacement hormone. This thyroid replacement hormone will first be introduce with a low those, there after it will increase until she reaches normal T4 and TSH levels. The negative result of this medication is the increased risk of developing osteoporosis. Therefore Margie should eat high calcium diet with calcium and vitamin D
supplements.
It was to this respect that, the search could detect ‘’hypertension’’ as the leading risk factor for heart disease. And this preceded three quarters of heart failures cases as compared to coronary artery disease, which led to most heart failures in less than 40% of the cases. Also, an increase in left ventricular end-diastolic diameter became a mirror to the Framingham study as incident heart diseases in the individuals who are free from myocardial infarction. Although studies have shown that, the manifestation of heart failures can be present without the left ventricular systolic dysfunction, other risk factors could lead to that. Also, they (Framingham study) were able to detect ‘’too much of cholesterol’’ as a link to cardiovascular diseases. Moreover, research believed that has elevated among certain heart diseases such as coronary heart often leads to stroke, too high blood pressure among numerous patients. Having said that, the search discovered ‘’obesity’’ also as a concomitantly with hypertension which elevates lipids and diabetes versus questions on smoking behavior. Having said that, these risk factors are believed to have attributed to heart diseases. Therefore, it became a national concern to the general US population and that of the fourth director of Framingham heart study, William Castelli
Answer: The evaluated group of 500 patients within this study is considered to be a sample. The 500 patients whom possess high cholesterol are comprised of the larger group of patients of which serve holistically as the population. The 500 patients randomly selected from the total population with high cholesterol of which 67% were found with heart disease constitute as the sample.
Graves’ disease is an autoimmune disease that was discovered by Robert Graves in 1835. Graves’ disease is an autoimmune disease in which the body's immune system attacks the thyroid gland and causes hyperthyroidism. Graves’ disease occurs when the antibodies like thyroid-stimulating immunoglobulin and thyrotropin receptor antibodies (TRAbs) attack the thyroid gland as if it were a foreign object or a virus of some sort. This disease is the most common type of hyperthyroidism. Attacking the thyroid gland in such a manner makes it excessively overproduce the hormone thyroxine which controls the body’s metabolic rate. Heightened activity of the thyroid can increase the body’s metabolism by 60% to 100%. (Weeks 34-35).
Hypercholesterolemia is the presence of high levels of cholesterol in the blood. Cholesterol is a waxy fat-like substance and is a major class of lipid, so it gets into the blood by lipoproteins [1]. A high level of lipoproteins is unhealthy. A high level can result in an elevated risk of atherosclerosis and coronary heart disease [2]. The high levels of lipoproteins are often influenced by a combination of genetic and environmental factors such as obesity or dieting habits [2]. High cholesterol can be caused by mutations in the following genes: APOB, LDLR, LDLRAP1, and PCSK9 [3]. Mutations in the LDLR gene are responsible for causing familial hypercholesterolemia, which is the most commonly seen form of inherited high cholesterol [3]. The LDLR gene contains instructions for making LDL receptors or low-density lipoprotein receptors. LDL receptors play critical roles in regulating levels of cholesterol in the blood by removing low-density lipoproteins from the bloodstream. Mutations in the LDLR gene can make the amount of LDL receptors produced less than normal or affect their job of removing the low-density lipoproteins in the blood [4]. People who have these mutations will have higher levels of cholesterol. There are many ways that the environment can affect the levels of cholesterol in the blood. Reducing the amount of dietary fat you consume lowers the total amount of cholesterol in the blood [5]. Sucrose and fructose can raise the amount of LDL in the blood. Reducing fatty foods will however lower the amount of LDL [5]. Having a healthy body and maintaining physical exercise plays a key role in keeping your cholesterol at a healthy level. If you are overweight or obese you can lower your cholesterol levels by simply losing ...
The following presentation will help this class in the teaching of a patient with hypothyroidism. The expected outcome of this presentation for the patient will be as follows:
The thyroid gland is found in the front of the neck and produces two main hormones. The hormones are called thuroxine (T4) and Triiodothyronine (T3). Together these hormones regulate the body’s metabolism by increasing energy use in cells, regulate growth and development, help to maintain body temperature and aid in oxygen consumption. These two hormones are regulated by hormones produced by the hypothalamus and pituitary gland. The hypothalamus senses changes in body’s metabolic rate and releases a hormone known as thyropin-releasing hormone (TRH). This hormone then flows through connecting vessels to the pituitary gland which signals it to release another hormone. This hormone is known as thyroid-stimulating hormone (TSH). TSH then makes its way to the bloodstream until it reaches the thyroid where it is then signaled to activate T3 and T4 production [1]. This mechanism is controlled by a negative feedback loop meaning that when there is a sufficient amount of thyroid hormones in the blood stream, this will signal back to stop production of thyroid stimulating hormones. Complications occur when the thyroid hormones keep increasing even though there is already a sufficient amount of T3 and T4 in the blood stream. This process of over expression of thryroid hormones is known as hyperthyroidism. Hyperthyroidism is a general term that includes any disease that has a consequence of an overabundance of thyroid hormones. Hyperthyroidism is a general term but there are many variant diseases that are in the hyperthyroidism category. These diseases include diffuse toxic goiter, Basedow’s disease, thyrotoxicosis, Parry’s and Graves’ disease.
Among these disorders are hypothyroidism and hyperthyroidism. Hypothyroidism is a disorder in which one is diagnosed for having and underactive thyroid. The probability for women over the age of sixty to develop an underactive thyroid is higher than those of other individuals. If left untreated it can potentially lead to obesity, joint pain, heart disease, and other health complications. On the contrary, hyperthyroidism is a disorder in which a person is diagnosed for having an overactive thyroid. This can cause nervousness and anxiety, hyperactivity, unexplained weight loss, and swelling of the thyroid gland which causes a noticeable lump to form on throat (known as a
Increasingly, scientists are focusing on a common set of underlying metabolic issues that raise people's risk for chronic disease.
Our patient has 4 of the 5 risk factors: low HDL, high triglycerides, high fasting blood glucose, and central obesity. Because of this, she does seem to have metabolic syndrome. With metabolic syndrome concomitant disease states occur that the patient may have, including PCOS, and hypothyroidism.
Taking a look into hyperparathyroid, it is characterized as having a excess secretion of the parathyroid hormone PTH and calcium. This condition can be classified as primary, secondary, and tertiary. Primary hyperthyroidism occurs when there is a excess amount of PTH being secreted by more than one the the parathyroid glands (470). This know as one of the most common conditions and is possibly caused by genetics. As explained by AUTHOR the PTH is not under the control of the feedback mechanisms and this causes calcium levels in to blood to be increase (470). Secondary is known to be a compensatory response. This occurs because there is chronic
Hypothyroidism, also known as underactive thyroid is a condition of the endocrine system, in which the thyroid gland is located. The gland can be found in front of the trachea and just below the Adams apple. This gland produces thyroxine (T4) and tri- iodothyronine (T3) which helps secretes hormones to the body (Mendes, 2015). “Hypothyroidism is caused by the thyroid gland not being able to produce enough T3 and T4 to the body; it can also be caused by the inadequate production of thyrotropin which is produced by the pituitary gland” (Gregory, 2014).
Due to her Hashimoto’s diagnosis JJ should begin pharmacologic treatment. The mainstay for treatment of hypothyroidism is levothyroxine4. Levothyroxine is synthetic T4 that comes in a variety of strengths and is a relatively cheap generic medication. Levothyroxine has a simple method of action, it replaces T4 hormone that the patient’s thyroid cannot produce and once in the blood stream acts just like natural T44. The starting dose for this medication is patient is under 50 years old is 1.6 mcg/kg daily4. JJ is currently 73 kg, so she should be started on the levothyroxine 112 mcg daily. When being counseled JJ should be told to take her medication once daily every morning 30 minutes before breakfast, this is because levothyroxine is best absorbed on an empty stomach and this environment is needed to get the full dose4. Although not preferred, if this method of taking her medication does not work for JJ she can take her one tablet daily 4 hours after her last meal of the day, or take her entire weekly dose once a week4. JJ should be told that the onset of action for levothyroxine is about 3-6 days; she could experience increased heart rate, weight loss, fever, or tremors5. Levothyroxine has some drug interactions that pertain to medications JJ is on. Levothyroxine and
Reasons for thyroid surgery can range from known or suspected thyroid cancer to one or more enlarged nodule that cause swallowing or breathing problems. Just as the reasons for surgery can vary, there are several surgical solutions that range from traditional operations to minimally invasive procedures. A Victorville or Glendora General Surgeon will analyze your individual situation. The surgeon will recommend the best procedure, based on your particular symptoms and overall health status. You will be given pre and post-surgery instructions on how to care for the surgical site, when to resume your daily activities, and when to schedule checkups in the surgeon’s office. If the entire thyroid is
With this in mind, the physician often suggests a blood sample to be taken for analysis of the thyroxine hormone levels at each annual physical (Litin, 1017). An underactive thyroid is characterized by many symptoms, and if shown at an earlier age the doctor may also draw blood to test. The family medical history of the patient is an important collection as well. If the patient has a parent, grandparent or close relative with an autoimmune disease, the need to test for hypothyroidism increases significantly (Litin, 1018). Through the testing of the patient’s levels of thyroid stimulating hormone (TSH) and thyroxine, the physician will be able to correctly diagnose their symptoms as a result to having hypothyroidism. In response to not receiving enough thyroxine, the pituitary will make extra TSH – in an attempt to persuade the thyroid to produce more hormone (Norman). The constant flourish of high TSH causes the thyroid gland to become a goiter by enlargement (Norman). It is noted that low levels of the hormone thyroxine with a combination of high levels of TSH, is an affirmation sign of hypothyroidism (Litin, 1018). Once the patient is correctly diagnosed, the physician may begin treating the
Keeping track of cholesterol, weight, blood pressure, and blood sugar levels plays a vital role in preventing the disease and maintaining excellent physical wellness. As stated, scheduling and attending annual physical exams, avoiding tobacco products, adequate sleep, and a regular exercise routine will drastically reduce the risk of these diseases as well. It's important to recognize that sleep is an absolutely crucial component of optimal health and disease prevention. There is a vast difference in the potential for preventing morbidity and mortality from CVD, diabetes, and cancer through healthy living than with unhealthy living. Sources: