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Case Studies Of Early Onset Alzheimers Disease
INTRODUCTION TO alzheimer's disease
Introduction for alzheimers research paper
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Alzheimer’s is a progressive mental deterioration disease that can occur in middle or old age, due to generalized degeneration of the brain. It is a neurological disease. Alzheimer’s is a serious disease that causes brain cell death and memory loss. It is the most common cause of premature senility. Alzheimer’s is a very common disease, and more than 5 million American’s are living with it currently. Astonishingly, Alzheimer’s disease is the 6th leading cause of death in the United States. Some of the other facts about Alzheimer’s are: Every 67 seconds someone in the U.S. develops Alzheimer’s. There are approximately 500,000 people dying each year because they have Alzheimer’s. One in three seniors dies with Alzheimer’s or another dementia. …show more content…
One of these symptoms is the worsened ability to take in and remember new information. Some examples of this would be repetitive conversations and questions, forgetting appointments or important events, misplacing personal belongings, or getting lost on routes that are familiar. People can also experience impairments to things such as judgment, performing tasks, and also reasoning. Impaired speaking, writing, reading, and visuospatial abilities can also be signs and symptoms of Alzheimer’s. People’s behavior can change, and their personality can be altered. Loss of empathy, agitation, motivation, and social withdrawal are all …show more content…
It has been discovered by genetic research that there is a link between Alzheimer’s disease and genes on four chromosomes. These genes have been given a label numerically with the numbers 1, 14, 19, and 21. A gene on the chromosome 19 has been related to the the late onset of Alzheimer’s disease. Dozens of studies across the globe have confirmed that one particular strain of the gene, also known as APOE4, heightens the chance of developing Alzheimer’s disease throughout your lifetime. Strangely, one of the mysteries about APOE is that some people that have the APOE4 variant, or the most common variant, do not develop Alzheimer’s in their later years of life. Also, some people develop the disease even if they don’t inherit APOE4. So, even if APOE increases the chance of developing Alzheimer’s disease, it is not a consistent marker to determine if Alzheimer’s is genetically inherited or not. There is no specific age onset for Alzheimer’s, however, the early stages can occur during a person’s 30’s, 40’s, and 50’s. However, the symptoms of Alzheimer’s disease don’t typically become noticeable until a person is older than 65 years of
Alzheimer is a dementia type of disease named after Dr. Alois alzheimer that slowly destroys memory and thinking skills,and eventually , the ability to do simple things, or recognize their family. The first case occurred in the 1906 when a woman died on a unusual mental illness. After she died Dr.Alois examined her brain , amyloid plaques and neurofibrillary. Alzheimer’s is in older people the most common cause of dementia. Dementia is a loss of remembering ,thinking and reasoning skills, that intervenes with your daily life and activities. It is very common in people over sixty years of age. People younger than sixty years can also
Alzheimer’s disease is a form of dementia affecting the older population. Symptoms are more noticeable over time due to the severity of the stages worsening. Alzheimer’s is the most common form of dementia. It accounts for fifty to eighty percent of dementia cases. Contrary to belief Alzheimer’s is not a normal part of aging. Different parts of the brain are affected causing multiple symptoms sometimes not diagnosed until later stages in the disease.
Alzheimer’s can be diagnosed before age 65, although rare, and is caused by a mutation in 3 known genes. About 5 percent of those who are under 65 and possess the ailment have AD in their family history. Given that the symptoms of AD are caused by plaque in the brain, causing loss of nerve cells that help the body communicate with the brain, mutations to these genes; amyloid precursor protein, presenilin 1, and presenilin 2 cause a excessive production of certain proteins (primarily a B-42 form of amyloid protein), and therefore spark an excessive growth of plaque cells which are toxic to the neurons of the brain. For those cases of Alzheimer’s that occur after age 65, a genetic mutation has yet to be proven, although some may be linked, to the fact that a difference may cause an increased chance of developing the ailment. Whatever the case may be for patients over 65 years old, the disease and its symptoms are caused by neurofibrillary tangles of almyloid plaques. It is impossible for someone to test positive for Alzheimer’s Disease, because the only way to determine an affirmative case i...
of diagnosis is about 80 years old (Johnson, 1989). The incidence is about the same for all races, but women are more likely than men to develop the disease, because they live longer. The second factor is heredity. Family history plays a role in about forty percent of people with early onset of Alzheimer’s (Johnson, 1989). If your parents or a sibling developed the disease, you are more likely to, as well. But there are cases of families with several people who have had this disease and other members are not affected. These two factors are the only proven factors, but environmental research is being done to help with a possible protective effect for the disease. As of now, more research is needed to confirm any be...
An article from The New York Times claims that there is a high mortality rate from Alzheimer’s disease. The Centers for Disease Control and Prevention estimated that, in 2010, the disease caused nearly 84,000 deaths directly and another 500,000 deaths from conditions caused by Alzheimer’s (The Editorial Board 2014).... ... middle of paper ... ...
As with any disease there are factors that may put one at more risk for developing the disease. The most common risk factor is age. After 65, the likelihood of developing Alzheimer’s disease doubles every 5 years - this means as you age you are more likely to be diagnosed with Alzheimer’s. Although, in early onset, people can be diagnosed as early as in their thirties - there are 500,000 people in America living with early onset Alzheimer’s. Being female is another risk factor. Women are more likely than men to be living with Alzheimer’s. Two-thirds of people living with Alzheimer’s in America are women. Another risk factor is genetic predisposition or family history. Some avoidable risk factors involve head injury and heart health...
Alzheimer’s disease comes from the last name of a neuro-psychiatrist from Germany, Alois Alzheimer. The disease was first diagnosed when a woman in her early fifties began experience memory problems. “Alzheimer recounted the now famous case of ‘Auguste D.’ a 51-year-old housewife who had been failing mentally for several years. As a result she had been admitted to his care in the Asylum for the Insane and Epileptic…” (Maurer and Maurer 1). After her death, he continued to examine her brain to find causes and explanations for her behavior. He discovered “…classic neuro-pathological signs of plaques and tangles” (Maurer and Maurer 1). “Plaques are chains of amino acids that are pieces of the amyloid precursor protein…tangles are aggregates of the protein tau” (Secko 1). As plaques develop they produce tangles and “these two abnormalities ultimately lead to loss of cognitive function” (Secko 1) Alois Alzheimer’s research has allowed many specialist to conclude that the apolipoproetein E gene may contribute to the disease.
This disease causes memory loss, difficulty in thinking processes, mood swings, depression, hallucinations, personality changes, and the inability to create new memories. Alzheimer’s disease is most common in people who are at the age of sixty years or older, but it can start as early as the age of nineteen. It can be categorized as a type of dementia. “Scientists believe Alzheimer’s disease prevents parts of a cell’s factory from running well” (Alzheimer’s Disease: The basics). Scientist believe that one cause of Alzheimer’s could be caused by plaques and tangles. Plaques are the build up of a protein called beta-amyloid in the nerve cells. Tangles are twisted fibers of the tau protein that build up inside of a cell. The exact cause of Alzheimer’s has not yet been determined, but scientists have reason to believe that it is because these plaques and tangles are blocking the communication of cells in the nervous system. Another probable cause is a mutation on the chromosomal genes 21, 14, and 1. This is why it is believed to be a genetically inherited
Alzheimer’s disease is a form of dementia which is a brain disorder that impairs mental functioning. Dementia attacks the part of the brain which controls memory, language, and thought. It makes everyday tasks like remembering to brushing your teeth, or to pay your bills next to impossible to do, which is why so many people who are diagnosed with this disease are in complete care. This disease has different phases, the first being slight forgetfulness and then the persons emotions may heighten as well as language impairment, violent outbursts, loss of bladder control and from there it keeps getting worse until complete dysfunction of the brain occurs and eventually death, which most of the time is the result of infection.
Alzheimer's Disease Introduction to Alzheimer's Alzheimer's disease is a progressive, degenerative disease of the brain. It was first described by the German neuropathologist Alois Alzheimer (1864-1915). in 1905. This disease worsens with advancing age, although there is no evidence. that it is caused by the aging process.
I know that there is no cure for Alzheimer's disease and that you just have to take it one step at a time. Families have to learn how to deal with a loved one who has Alzhemier's disease; it will not be very easy. I know that Alzheimer's disease is when people get confused and lose their memory. You never know when you will get Alzheimer's disease or if you will even get it. It is just something that happens, that you and your family have to learn how to live with it.
Alzheimer's disorder is a mental disorder that affects your brain, and in particular the disorder affects the memory part of your brain. The disorder slows down the memory section of your brain, and as a result the number one symptom of Alzheimer's is memory loss. The disorder usually doesn't affect younger people, but instead affects people that are older than the age of sixty. The disorder can get so serious that the patient could loss there of about everything that has ever happened in their life. Patients usually loss their memory of their childhood during the most severe, intense, and last stage of the disorder. Alzheimer's disorder can also have a drastic effect on the patient's family, because during the disorder the patient can forget about their entire family.
Alzheimer disease generally occurs in people over seventy five years of age; however it does strike people in their forties, fifties, and sixties, but this is rare. When Alzheimer’s disease occurs prior to the age of sixty five, it is referred to as early onset Alzheimer’s.
...eryday Alzheimer’s is impacting the lives of many and it is time to fight Alzheimer’s disease right back. 2.4 million to 4.5 million are diagnosed every year in the United States and one day will hopefully none will be diagnosed.
Mykenzie Moyle Ms. Douglass English I, P.4 16 May 2014 Research Paper Alzheimer’s Disease is formed in the brain but, yet, has no known cure or treatment. Alzheimer’s disease has many symptoms. Memory is the biggest symptom along with mood swings and having a hard time keeping up with a conversation. A patient with Alzheimer’s goes through 7 stages; The first stage, which is misplacing things or forgetting what something is used for, second stage, they start losing more of their memory and they begin to forget where they are or what they are doing, the third, fourth and fifth begin to mentally decline and need someone to take care of them and worsen over time.