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Short notes on diabetes mellitus
Gestational diabetes mellitus research paper
Gestational diabetes mellitus research paper
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Diabetes mellitus, habitually referred to as diabetes is caused by a decline in insulin secretion by the cells of the pancreatic islet resulting into a surge in blood glucose concentration, a condition known as hyperglycemia. Diabetes insipidus is a disorder defined by the secretion of huge quantities of highly diluted urine, this is regardless if a reduction in fluid intake. This is as a result of a deficit of anti-diuretic hormone (ADH) also known as vasopressin produced by the posterior pituitary gland. The disorder diabetes mellitus is associated by extreme reduction in weight, a higher urge for urination, also known as polyuria, higher levels of thirst (polydipsia) and an extreme craving to eat known as polyphagia. This disorder has been categorized as Type 1 or insulin dependent diabetes and Type 2 or non-insulin dependent diabetes another type is the Gestational diabetes. The Type 1 diabetes mellitus is portrayed by a deficiency of the insulin-secreting beta cells of the islets of Langerhans found in the pancreas, this leads to a shortage of insulin. The principal cause for this deficiency of beta cells is a T-cell mediated autoimmune onslaught. In children, Type1 diabetes is known as juvenile diabetes. The Type 2 diabetes mellitus is as a result of insulin resistance or diminished insulin sensitivity coupled to a reduction in insulin production. The faulty responsiveness of body tissues to insulin normally entails the insulin receptor found in cell membranes. The other type, the gestational diabetes happens in women who have not been diagnosed with diabetes before and show elevated blood glucose amounts during pregnancy. There is no explicit reason that has been acknowledged but it is assumed that the hormones secreted dur... ... middle of paper ... ... to demonstrate that hemoglobin attaches to the VIVO2+ ion at two locations of comparable strengths, named β and γ. This study has also proven that the interaction of red blood cells cannot be ignored when the conveyance or the pharmacological properties of a V compound is taken into consideration. In general, this paper does well in supporting the information available concerning hemoglobin. This article boosts the information available, concerning the diseases, genetics and functions of hemoglobin proteins. The authors achieve this by getting down to the basic level via the examination of the crystallographic structures of hemoglobin. This research has demonstrated novel examples associated with hemoglobin, pertaining to its processes and its purpose of movement. This study has immense implications for the grasp and the management of various diseases of hemoglobin
Case study: Carol is 17 years old and was diagnosed with Type 1 diabetes at the age of 7 years. Carol has had a recent hospital admission for dehydration and high blood glucose. During the admission Carol was found to be 6 weeks pregnant. Prior to the admission she had been experiencing weight loss and changes in mood.
According WebMD 2014. Diabetes mellitus (or diabetes) is a chronic, lifelong condition that affects your body's ability to use the energy found in food. There are three major types of diabetes. Type 1 diabetes mellitus, type 2 diabetes mellitus and gestational diabetes. It is a hormonal disorder of the pancreas either decrease in insulin level also known as hypoinsulinism or increase in insulin level also known as hyperinsulinism. Lowered amounts, insufficient of, or ineffective use of insulin leads to the disorder of diabetes mellitus. It is common chronic disease requiring lifelong behavioral and lifestyle changes. According to Peakman (2012). The development of type 1 diabetes mellitus is a genetic and an autoimmune process that results in destruction of the beta cells of the pancreas, leading to absolute insulin deficiency. There is usually a pre-diabetic phase where autoimmunity has already developed but with no clinically apparent insulin dependency. Insulin autoantibodies can be detected in genetically predisposed individuals as early as 6-12 months of age. In persons genetically susceptible to type 1 diabetes, a triggering event, possibly a viral infection the leads to production of autoantibodies that kill the beta cells and results in decline and a lack of insulin secretion. According to Wherrett. It is caused by impaired insulin secretion and insulin resistance and has a gradual onset. Those with type 2 diabetes may eventually need insulin treatment. Gestational diabetes mellitus is glucose intolerance during pregnancy in a woman not previously diagnosed with diabetes, this may occur if placental hormones counteract insulin, causing insulin intolerance. Complications in diabetes mellitus includes: Hypoglycemia it is ca...
The pathophysiology of diabetes mellitus in is related to the insulin hormone. Insulin is secreted by cells in the pancreas and is responsible for regulating the level of glucose in the bloodstream. It also aids the body in breaking down the glucose to be used as energy. When someone suffers from diabetes, however, the body does not break down the glucose in the blood as a result of abnormal insulin metabolism. When there are elevated levels of glucose in the blood, it is known as hyperglycemia. If the levels continue to remain high over an extended period of time, damage can be done to the kidneys, cardiovascular systems; you can get eye disorders, or even cause nerve damage. When the glucose levels are low in one’s body, it is called hypoglycemia. A person begins to feel very jittery, and possibly dizzy. If that occurs over a period of time, the person can possibly faint. Diabetes mellitus occurs in three different forms - type 1, type 2, and gestational.
Diabetes mellitus also known simply as diabetes refers to a group of metabolic diseases which affect the body’s homeostatic mechanism used for maintaining and regulating the body’s blood sugar levels. Diabetes is a chronic condition which, in 2013 was estimated to be affecting 382 million people worldwide.[1] People suffering from diabetes are required to constantly be vigilant of their blood sugar levels to ensure it does not go below or above optimum levels. Depending on the type of diabetes and glucose level range, they may need to inject themselves with insulin or eat high sugar foods to restabilise their body. Failure to do so can lead to other long term health effects.[2]
Throughout the whole of the United Kingdom, between 2 and 3 of every 100 people have a known form of diabetes (DTC, 2004). What is diabetes? Explained simply, it is a disease in which the body does not produce or properly use insulin. In the normal state of glucose function, there is a stable release and uptake of glucose, regulated by two hormones produced in the pancreas, glucagon and insulin. There are two distinct mechanisms which give rise to the abnormal blood glucose levels seen in patients with type I and type II diabetes. In type I diabetes, a deficiency in insulin production at the pancreas results in elevated blood glucose levels due to the lack of hormonal regulation. In type II diabetes, although the pancreas produces regular levels of insulin, the body resists the effect of insulin, inhibiting the ability of insulin to break down glucose in the blood. Because of the inherent differences in the biochemical mechanisms of these two diseases, the characteristics associated with type I and type II diabetes are very different. The typical onset of type I diabetes is usually ...
Type 1: Is an Autoimmune disorder in which no insulin is being produced affecting only 5-10% of people with diabetes and is more common in Caucasians with a typical onset before the age of 30. There aren’t many risk factors for Type 1 Diabetes, but some known ones include, Family History, Genetics, and Geography. Other possible ones are Viral exposure or viral infections, early drinking of Vitamin D (cow’s milk), and other dietary factors such as drinking water with nitrates may also increase the risk.
Diabetes is a disease that affects the body’s ability to produce or respond to insulin, a hormone that allows blood glucose (blood sugar) to enter the cells of the body and be used for energy. Diabetes falls into two main categories: type 1, or juvenile diabetes, which usually occurs during childhood or adolescence, and type 2, or adult-onset diabetes, the most common form of the disease, usually occurring after age 40. Type 1 results from the body’s immune system attacking the insulin-producing cells in the pancreas. The onset of juvenile diabetes is much higher in the winter than in the summer. This association has been repeatedly confirmed in diabetes research. Type 2 is characterized by “insulin resistance,” or an inability of the cells to use insulin, sometimes accompanied by a deficiency in insulin production. There is also sometimes a third type of diabetes considered. It is gestational diabetes, which occurs when the body is not able to properly use insulin during pregnancy. Type 2 diabetes encompasses nine out of 10 diabetic cases. Diabetes is the fifth-deadliest disease in the United States, and it has no cure. The total annual economic cost of diabetes in 2002 was estimated to be $132 billion, or one out of every 10 health care dollars spent in the United States. Diabetes risk factors can fall into three major categories: family history, obesity, and impaired glucose tolerance. Minority groups and elderly are at the greatest risk of developing diabetes.
Diabetes mellitus type 2 is an endocrine disorder that causes impaired use of carbohydrates while enhancing the use of proteins and lipids. This is called insulin resistance, in which the pancreas cannot make enough insulin to keep blood glucose levels normal, or the body is unable to use what is produced. The impairment causes blood glucose level to rise higher than normal. There is no cure for type 2 diabetes mellitus and it is life threatening when left untreated. Signs and symptoms of this disorder include vision changes, increased thirst, increased hunger, increased frequency of urination, stomach pain, nausea and vomiting, erectile dysfunction, and absences of mentruation. These can occur abruptly, or over a long period of time. Long-term complications from diabetes include kidney damage, eye damage, and blindness. The risk factors for developing diabetes mellitus include genetics, sedentary lifestyle, high blood pressure, history of diabetes during pregnancy, poor diet, obesity, high cholesterol, and abdominal obesity. Diabetes mellitus can be managed through the use of medication, or by reducing risk factors, such as avoiding obesity, inactivity, and poor nutrition.
Diabetes is a group of metabolic diseases in which the person has very high blood sugar. This is either because the production of insulin is inadequate or because the body cells do not properly respond to insulin. Obesity, on the other hand, is a health condition whereby excess body fat has accumulated to an extent where it has a negative effect on health. This leads to reduced life expectancy and increased health problems. Diabetes and obesity are closely tied as doctors highly link diabetes to people’s weight problem. This study focuses on the relationship between obesity and diabetes and the care for patients suffering from these conditions.
Diabetes mellitus is a group of metabolic disorders characterized by inadequate insulin secretion by the pancreas or cellular destruction leading to an insulin deficiency. Depending on the cause of the insulin shortage, diabetes can be subcategorized into type I and type II. Type I diabetes (T1DM) is usually mediated by the destruction of b-cells in the pancreas resulting in decreased insulin production and secretion. Type II diabetes (T2DM) is the failure of these b-cells to secrete adequate amounts of insulin to compensate for insulin resistance and increased gluconeogenesis combined with an overall resistance to the insulin action (8., 1997). T2DM accounts for 90 to 95 percent of all diabetes cases.
Pregnancy should be a time of happiness for women, but woman who have complicated pregnancies are faced with various problems that can make their pregnancy even stressful than it already is. One of the complications of pregnancy that women go through is Gestational Diabetes. Gestational Diabetes can occur in woman who are 24 and 28 weeks pregnant. It is a condition when women develops high levels of blood glucose. It has affected 18 percent of pregnant woman worldwide.( Healthline,2014).Women who are already diagnosed with diabetes think that they are at high risk for Gestational diabetes, but this could rarely be the case. The cause of this complication is still unknown but hormones can be the main factor in why it develops. When a woman is pregnant she produces more excessive hormones, In time the hormones may interfere with the action of insulin and without insulin working properly blood glucose levels are increased causing gestational diabetes(healthline,2014).
Gestational diabetes mellitus (GDM) is an intolerance of glucose documented for the first time during pregnancy. It is usually a short-term type of diabetes and the most common health problem with pregnant women. GBM is caused by the way the hormones in pregnancy affect the mother. GDM accounts for 5-7% of all pregnancies (American Diabetes Association, 2010). During pregnancy the placenta develops and becomes the main bond between the mother and the baby. It is used to make sure the baby has and gets enough nutrients. The placenta makes several hormones which make it hard for insulin to control blood glucose and block the action of the mother’s insulin in her body (American Diabetes Association, 2010). Hormonal changes during the pregnancy causes the body to be less sensitive to insulin. Insulin has the job of opening up the cells so that the glucose can get inside regulating the amount of glucose in the blood while glucose is the amount of sugar in the blood stream. In pregnancy, the body needs to make three times more insulin for control of the blood sugar. GDM is usually found within the second trimester of a pregnancy and increases until the end of the pregnancy. Usually within a few hours of delivery the condition resolves itself (American Diabetes Association, 2010).
Diabetes Mellitus is a chronic condition which afflicts millions of people around the world. It is related to the insulin hormone, which is secreted by cells in the pancreas, regulates the level of glucose in the bloodstream and supports the body with breaking down the glucose to be used as energy. In someone who has diabetes, the body doesn’t produce enough insulin or cells don’t respond to the insulin that is produced. There are three main types of diabetes, type 1, type 2, and gestational. I will be discussing type 1 and type 2.
Gestational diabetes is a form of diabetes that occurs during pregnancy. Although it usually goes away after the baby is born, it does bring health risks for both the mother and baby. When you’re pregnant, pregnancy hormones make it harder for insulin to move glucose from your blood into the cells. If your body can’t produce enough insulin to overcome the effects of insulin resistance, you’ll develop gestational diabetes. (IHC, 2013)
Diabetes mellitus (DM) or simply diabetes, is a chronic health condition in which the body either fails to produce the amount of insulin needed or it responds inadequately to the insulin secreted by the pancreas. The three primary types of diabetes are: Diabetes Type 1 and 2, and during some pregnancies, Gestational diabetes. The cliché for all three types of diabetes is high glucose blood levels or hyperglycemia. The pathophysiology of all types of diabetes mellitus is related to the hormone insulin, which is secreted by the beta cells of the pancreas. This hormone is responsible for maintaining an optimal glucose level in the blood. It allows the body cells to use glucose as a main energy source. Due to abnormal insulin metabolism, in a diabetic person, the body cells and tissues cannot make use of glucose from the blood, resulting in elevated blood glucose level or hyperglycemia. Over time, elevated blood glucose level in the bloodstream can lead to severe complications, such as disorders of the eyes, cardiovascular diseases, kidney damage and nerve destruction. In Type 1 diabetes, the pancreas is not able to produce sufficient amount of insulin as required for the body. The pathophysiology of type 1 diabetes suggests that it’s an autoimmune disease, in which the body’s own immune system generates secretions of substances that attack the beta cells of the pancreas leading to low or no insulin secretion. This is more common in children and young adults before the age of thirty. Type 1 is also referred as Insulin dependent Diabetes Mellitus or Juvenile Diabetes, exogenous insulin is needed for its treatment. In type 2 diabetes mellitus we find insulin resistance with varying degrees of insulin secretory defects and is more comm...