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DNA Computing
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Recommended: DNA Computing
1. Introduction:
DNA Computing is a Bio-molecular Computation (BMC) which makes use of biological methods for performing massively parallel computation. This can be a lot quicker than a conventional Silicon Chip computer, for which large quantities of hardware needed for performing parallel computation. These DNA computers [] don’t just make use of massively parallel computation, but also uses ultra-compact information storage in which large amount of information that can be stashed in a more compact away with which massively exceeds in conventional electronic media, (i.e., A single gram of DNA[] comprises 1021 DNA bases which equals to 108 terabytes. A hardly few grams of DNA possibly contains all data stored in world.
This cross-topical field of DNA Computing combines the ideas from biological sciences, computer science and chemistry. In 1994, Leonard M. Adleman [] designed a study to solve the Travelling Salesman problem that attempts to visit each city exactly once and try to find every possible route using molecules of DNA. Hence, this inspired model provides the potential ability of working out many problems that were previously thought impossible or exceedingly difficult to solve out with the traditional computing paradigm such as encryption breaking, game strategy etc.
As Power of the parallel processing is increasing day to day, modern cryptosystems can be easily cryptanalyzed by the cryptanalyst, the world is looking for new ways of information and network security in order to protect the data as it carries. The idea of using Bio-Molecular computation in the areas of cryptography to bring up a promising technology for providing of unbreakable algorithms, but these DNA cryptography lacks the related theory which ...
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...Uracil (U) and later these mRNA copies or transcripts can be translated into proteins.
Transcription initiates with an RNA polymerase that binds the enzyme which is responsible for copying DNA into RNA. These RNA polymerase binds to a thermodynamically favorable region of the DNA called a promoter. This promoter acts as the start signal for transcription. Its effectiveness at attracting RNA polymerase is one of the methods used to control how much of a protein is produced. As it elongates, the RNA strand peels away from the DNA. The RNA polymerase eventually reaches a region called a terminator, which causes it to release.
Translation:
Translation is also a process that contains the RNA copy of DNA to make a protein. i.e the mRNA sequence is translated into a sequence of amino acids as a result protein is formed. During translation, RNA molecule is responsible
Deoxyribonucleic acid (DNA) is an acclaimed extraordinary discovery that has contributed great benefits in several fields throughout the world. DNA evidence is accounted for in the majority of cases presented in the criminal justice system. It is known as our very own unique genetic fingerprint; “a chromosome molecule which carries genetic coding unique to each person with the only exception of identical twins (that is why it is also called 'DNA fingerprinting ')” (Duhaime, n.d.). DNA is found in the nuclei of cells of nearly all living things.
DNA is the genetic material found in cells of all living organisms. Human beings contain approximately one trillion cells (Aronson 9). DNA is a long strand in the shape of a double helix made up of small building blocks (Riley). The repeat segments are cut out of the DNA strand by a restrictive enzyme that acts like scissors and the resulting fragments are sorted out by electrophoresis (Saferstein 391).
In order to do this a polymer of DNA “unzips” into its two strands, a coding strand (left strand) and a template strand (right strand). Nucleotides of a molecule known as mRNA (messenger RNA) then temporarily bonds to the template strand and join together in the same way as nucleotides of DNA. Messenger RNA has a similar structure to that of DNA only it is single stranded. Like DNA, mRNA is made up of nucleotides again consisting of a phosphate, a sugar, and an organic nitrogenous base. However, unlike in DNA, the sugar in a nucleotide of mRNA is different (Ribose) and the nitrogenous base Thymine is replaced by a new base found in RNA known as Uracil (U)3b and like Thymine can only bond to its complimentary base Adenine. As a result of how it bonds to the DNA’s template strand, the mRNA strand formed is almost identical to the coding strand of DNA apart from these
DNA is the blueprint of life from its creation to its development and until its death. The discovery of the structure of DNA not only revolutionized science and medicine, but it also affected many other facets of existence: evolutionary, industrial, legal, and criminal justice. Its incarnation has benefitted American families and industries and spurred scientific innovation throughout the country. Aptly stated by Francis Crick, “your joys and your sorrows, your memories and your ambitions, your sense of identity and freewill, are in fact no more than the behavior of a vast assembly of nerve cells and their associated molecules. As Lewis Carroll’s Alice might have phrased it: ‘you’re nothing but a pack of neurons.’ [Watson and my] discovery illustrates how that is possible.”
In April of 1953, James Watson and Francis Crick published a game changing paper. It would blow the mind of the scientific community and reshape the entire landscape of science. DNA, fully knows as Deoxyribonucleic Acid is the molecule that all genes are made of. Though it is a relatively new term with regard to the age of science, the story of DNA and the path to its discovery covers a much broader timeframe and had many more contributors than James Watson and Francis Crick. After reading the paper the audience should have a better understanding of what DNA is, the most important experiments that contributed to its ultimate discovery and the names and contributions of the lesser-known scientists that helped Watson and Crick turn their idea
What has to happen for a gene to be transcribed? The enzyme RNA polymerase, which makes a new RNA molecule from a DNA template, must attach to the DNA of the gene. It attaches at a spot called the promoter.
Tsou, J. A., Hagen, J. A., Carpenter, C. L., & Laird-Offringa, I. A. (2002, August 05). DNA
DNA testing has been the center of attention in many criminal justice cases. The United States corrections centers have utilized the DNA testing process. Seventeen death row inmates have been exonerated by the use of these tests. Earl Washington was convicted of rape and murder in 1984. Although he confessed to the rape, he was also diagnosed as being mentally retarded. In October of 2000 Mr., Washington was given a DNA test and was excluded as the rapist and murderer. The Virginia Governor pardoned Mr. Washington after he had served 16 years in prison with 14 of them being on death row (ACLU, 2011). DNA testing has become the rule rather than the exception; but what happens with the DNA after a person has been acquitted, dismissed, or exonerated. Where does DNA go to die or does it? Is the DNA destroyed, or is it retained in miscellaneous databanks for further retrieval and use? In 2010, the United States Congress began a campaign designed to encourage the states to require DNA to be taken from suspects whether they had been charged with a crime or not. In the case of S. and Marper v the United Kingdom found that the retention of the applicants' fingerprints, cellular samples and DNA profiles was in violation of Article 8 of the European Convention on Human Rights. Is creating a policy in the United States that demand DNA from suspects helps in finding subsequent criminals or is it just leading to a track and trace policy?
DNA (deoxyribonucleic acid) is a self-replicating molecule or material present in nearly all living organisms as the main constituent in chromosomes. It encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses. Simply put, DNA contains the instructions needed for an organism to develop, survive and reproduce. The discovery and use of DNA has seen many changes and made great progress over many years. James Watson was a pioneer molecular biologist who is credited, along with Francis Crick and Maurice Wilkins, with discovering the double helix structure of the DNA molecule. The three won the Nobel Prize in Medicine in 1962 for their work (Bagley, 2013). Scientist use the term “double helix” to describe DNA’s winding, two-stranded chemical structure. This shape looks much like a twisted ladder and gives the DNA the power to pass along biological instructions with great precision.
For example such as medicine, it can be sometime possible to reading DNA sequences and find out how some diseases occur. It can sometimes be possible to fight some infectious diseases or any form of disease by changing the DNA codons which cause most of these problems.
Citation: Philips, T. (2008) Regulation of Transcription and gene expression in Eukaryotes. Nature Education 1(1)
The work of this company revolves around DNA. They have formulated techniques to decipher the very code of a human’s existence. DNA has always been the most complex structure in a human body. 23andMe has invested all its resources into unravelling this very structure, in a way that it benefits an individual to improve the health conditions, based on future health predictions.
Protein synthesis is one of the most fundamental biological processes. To start off, a protein is made in a ribosome. There are many cellular mechanisms involved with protein synthesis. Before the process of protein synthesis can be described, a person must know what proteins are made out of. There are four basic levels of protein organization. The first is primary structure, followed by secondary structure, then tertiary structure, and the last level is quaternary structure. Once someone understands the makeup of a protein, they can then begin to learn how elements can combine and go from genes to protein. There are two main processes that occur during protein synthesis, or peptide formation. One is transcription and the other is translation. Although these biological processes slightly differ for eukaryotes and prokaryotes, they are the basic mechanisms for which proteins are formed in all living organisms.
Secondly the gene has to be cut from its DNA chain. Controlling this process are many restriction endonucleases (restriction enzymes). Each of these enzymes cut DNA at a different base sequence called a recognition sequence. The recognition sequence is 6 base pairs long. The restriction enzymes PstI cuts DNA horizontally and vertically to produce sticky ends.
What is DNA? DNA is deoxriybonucleic acid which is a molecule that is in a double-helix structure described by James Watson and Francis Crick in 1953. DNA contains our genetic code which is composed of triphosphate molecules, which are also known as the ‘building blocks’ of DNA. There are four bases included in the DNA molecule they are called the four nitrogenous bases. The bases are Thymine, adenine, guanine (purines), thymine and cytosine (pyrimidines) (http://forensicsciencecentral.co.uk/dna.shtml). This shows that DNA isn’t so easy to understand, there is certain bases to make up the DNA molecule. This is important because it helps compose the pieces to DNA and helps find traces to the victim. “The more useful sources include blood, semen, vaginal fluid, nasal secretions and hair with roots” (http://forensicsciencecentral.co.uk/dna.shtml). This quote is important because it singles out the most occurrence of DNA. In order for DNA testing to take place scientists will have t...