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Essays about ethics in research
Ethics in basic sciences
Essays about ethics in research
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The purpose of the paper is to critique and analyze the research surrounding hepatitis experiments conducted at Willowbrook State School. More specifically, it will analyze the ethical concerns that have come to raise many questions over time about the experiments done. Between the years 1956, spanning approximately, 15 years until 1971, mentally handicapped children residing at the state school would be the subjects of an experiment in which they were intentionally infection with hepatitis (Frankenburg, 2017). The man who would conduct this study was Dr. Saul Krugman. Initially, Dr. Krugman was brought on to help rid the facility of the disease, which was spreading through the residents, due to the already crowded and unsanitary conditions …show more content…
In 1974 the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research worked in establishing a set of ethical guidelines, called the National Research Act, in which those performing research are to follow (Office for Human Research Protections, 2016). This Belmont review while not only helping to establish a set of ethical principles it also discussed the way in which this can be correctly applied. As a whole it addresses three main areas. These include the boundaries between practice and research, basic ethical principles including respect for persons, beneficence and justice and lastly their applications which consists of informed consent, risk versus benefit and the selection of research participants (Office for Human Research Protections, …show more content…
On one hand the basis of this research relied on the concept of it helping the good of society while completely taking away the autonomy, beneficence and justice of those in which it was conducted on the other (Nieswiadomy, 2012). Krugman’s intentional infection of the children for the purpose of experimenting and understanding more about the disease itself skewed the boundaries between practice and research. These tests served of no benefit to the children as they were not being treated. Justice is the concept of treating each person equally and get fair treatment (Nieswiadomy, 2012). The subjects being tested on were not only children but children suffering from a disease that already caused them to function as a lower mental capacity than
Those who were affected by the testing in hospitals, prisons, and mental health institutions were the patients/inmates as well as their families, Henrietta Lacks, the doctors performing the research and procedures, the actual institutions in which research was being held, and the human/health sciences field as a whole. Many ethical principles can be applied to these dilemmas: Reliance on Scientific Knowledge (1.01), Boundaries of Competence (1.02), Integrity (1.04), Professional and Scientific Relationships (1.05), Exploitative Relationships (1.07, a), Responsibility (2.02), Rights and Prerogatives of Clients (2.05), Maintaining Confidentiality (2.06), Maintaining Records (2.07), Disclosures (2.08), Treatment/Intervention Efficacy (2.09), Involving Clients in Planning and Consent (4.02), Promoting an Ethical Culture (7.01), Ethical Violations by Others and Risk of Harm (7.02), Avoiding False or Deceptive Statements (8.01), Conforming with Laws and Regulations (9.01), Characteristics of Responsible Research (9.02), Informed Consent (9.03), and Using Confidential Information for Didactic or Instructive Purposes (9.04), and Debriefing (9.05). These particular dilemmas were not really handled until much later when laws were passed that regulated the way human subjects could be used for research. Patients
Ethical violations committed on underprivileged populations first surfaced close to 50 years ago with the discovery of the Tuskegee project. The location, a small rural town in Arkansas, and the population, consisting of black males with syphilis, would become a startling example of research gone wrong. The participants of the study were denied the available treatment in order further the goal of the research, a clear violation of the Belmont Report principle of beneficence. This same problem faces researchers today who looking for an intervention in the vertical transmission of HIV in Africa, as there is an effective protocol in industrialized nations, yet they chose to use a placebo-contro...
The experiment lasted more than forty years and did not garner media attention until 1972, when it was finally made public by Jean Heller of the Associated Press to an outraged nation. The fact that a medical practitioner would knowingly violate an individual’s rights makes one question their bioethical practices. What gives doctors the right to make a human being a lab rat? When both of these case studies began in the earlier half of the 20th century, African Americans were still fighting for the most
1. Capp, Marshall B. "Ethical and Legal Issues in Research Involving Human Subjects: Do You Want a Piece of Me? -- Kapp 59 (4): 335 -- Journal of Clinical Pathology." BMJ Journals. J Clin Pathol, 18 Jan. 2006. Web. 11 Feb. 2012.
society so these experiments are not seen as heinous or inhumane. This Information is all revealed in the introduction. The author tells this from a moral standpoint. The social construct determines if a particular event is seen as good or bad. Experiment back then on people were seen as okay but if they were performed on they would be extremely tabooed. The government even participated in human experiments to show how okay it was back then. In Conclusion, I am convinced that these bias among the scientific community is what caused black people to still be afraid of the doctors to this day.
During the process of research, professionals collect data or identifiable private information through intervention or interaction. While this is a vital part of the scientific and medical fields, every precaution must be taken by researchers to protect the participants' rights. Ethics, outlined by the Belmont report; requirements, described by the Department of Health and Human Services (DHHS); and regulations, laid out by the Food and Drug Administration (FDA) are verified by an Institutional Review Board (IRB). This procedure assures that all human rights are safeguarded during the entire research process.
Hepatitis B Virus (HBV) is a virus that attacks the liver. The virus is transmitted through blood and bodily fluids. This can occur through direct blood-to-blood contact, unprotected sex, use of contaminated needles, and from an effected mother to her newborn during the delivery process. The majority of people do not have noticeable symptoms when they are first infected with the HBV. People who do not know they are infected with the HBV, their body can respond in different ways. I learned that some of the common symptoms of Hepatitis B infection include fever, fatigue, muscle or joint pain, loss of appetite, mild nausea, vomiting, and dark-colored urine. Some of the serious symptoms that require immediate medical attention and maybe even hospitalization are: severe nausea and vomiting, yellow eyes and skin (jaundice), bloated or swollen stomach.
Hepatitis is the inflammation or swelling of the liver. The inflammation can happen from different injuries or viral forms of a disease. People who experience hepatitis have the symptoms of malaise, nausea, vomiting, loss of appetite, fever and jaundice. There are six known forms of Hepatitis which are Hepatitis A, Hepatitis B, Hepatitis C, Hepatitis D, Hepatitis E and Hepatitis G. The presence of hepatitis in the body can be very risky and cause severe death if not taken care of. Hepatitis is a severe issue that affect many people around the world like third world countries and cross contamination can occur mainly in health care places due to the exposure of patients with the disease and accidents handling blood or instruments, Hepatitis A,B,C,D,E and G are distinct diseases that differ in transmission and vaccines to prevent them or cure them.
There is a disease spreading out in the world called Hepatitis C. It affects the liver and may cause the liver to fail. This disease is caused by a virus called Hepatitis C virus which is also known as HCV. About 32,000 people are affected with this disease per year only in the United States area. Some It’s a disease with many symptoms and many causes. of these symptoms are easy bruising, upset stomach and fever. These are just some of the many symptoms that come from the virus. Hepatitis Cs nature of the causative agent is determined by many things. The biological data of this disease is filled so much information. It is estimated that over 180 million people have gotten Hepatitis C and it is growing.
Development of Code of Ethics. In: McNeill PM, ed. The Ethics and Politics of Human Experimentation. New York, NY: Cambridge University Press; 1993:37-51.
Looking beyond the Nuremberg Code and applying it to modern medical research ethics, there are many challenges that it poses. Many have argued that the Code tries to provide for all unforeseen events, which restricts the researcher by requiring him to anticipate every situation, demanding the impossible. The most important contribution of the Code is the first principle, which says that voluntary consent of the human subject is absolutely essential. The subject involved should have legal capacity to give consent, should have free power of choice, as well as sufficient knowledge and comprehension of the experiment. This restricts that populations upon which some experiment may be conducted, since many do not have “legal capacity”. For instance, studies of mental illness and children’s diseases have been curtailed because neither of these populations has the legal capacity to give consent. Another group of people, prisoners, are never really able to give voluntary consent since they might be enticed by financial rewards, special treatment, and the hope of early release in exchange for participating in the human experimentation projects. British biostatitcian Sir Austin Bradford Hill also questioned whether it was important to inform a research subject who was receiving a placebo since it does...
Psychology, the scientific study of the human mind and its functions, has been giving us information regarding human behavior and decision-making since the late 1800’s. The field itself is one of the most controversial in all of science, especially when it comes to the morality behind psychologist’s experiments. Morality is the distinction between what is considered to be right or wrong behavior. The famous psychology experiment known as the Stanford Prison Experiment is notorious for being considered an “immoral” trial; however, it was accepted by society because it was conducted in the name of science. This raises one question: should science trump morality even if it means putting some people at risk?
In conclusion the cases that have been studied and overviewed have explained several important ethical issues that researchers face on a regular basis. The cases have shown the importance of being able to protect ones informants or the participants of a study. They have also shown the different ways to gain and receive informed consent which is another important aspect of social research.
A large controversy that has been brought to the attention of many people across the globe, is the topic of prisoners and medical research. Throughout history we see prisoners are used to test both harmless and harmful diseases for the sake of medical research. Although its seems like it's a good idea of used those who wronged the public, but the methods used to conduct these studies are quite the opposite of harmless. In history a great example of this is the Nuremberg Trials during World War II when Nazi doctors wrongfully tested on Jewish inmates. Prisoners should not be allowed to participate in medical research because they are unable to understand consent forms, they are considered a vulnerable population and they are sometimes tested unethically.
... action (Elliston, 1985). Peter Buxtun worked for the Public Health Service. While working there, he discovered proper medical treatment was being withheld from poor, black syphilis patients so that they could conduct experimental medical treatments on these patients. In 1972, Peter Buxtun went outside of the Public Health Services to expose this violation of human subjects. He made the decision that expose this mistreatment of human subjects, to the Associated Press, who later published the story. Even though whistleblowing considered as “snitching”, Peter Buxtun decided exposing this violation was the only way to right the horrific wrong of mistreating and harming human subjects. “For 40 years, the U.S. Public Health Service has conducted a study in which human guinea pigs, not given proper treatment, have died of syphilis and its side effects” (Perkiss, 2013).