Hemophilia Research Paper

Hemophilia is a genetic disorder that causes a person’s blood not to clot. This causes bleeding to continue without being stopped by blood clotting. The big issue of the disorder is when the person experiences internal bleeding, but only in some cases does this occur. There are different levels and types of hemophilia, but the main problem of blood not clotting is always present. Although a person can be treated so that they can live active, hemophilia may last for the person’s whole life.

The cause of hemophilia is when there is a mutation on the X chromosome. Different types of the disorder have different causes. For example, hemophilia A is when there is blood clotting in factor 8. Hemophilia B is result of factor 9 blood clotting and hemophilia

C is when there is blood clotting in factor 11. Different types of the disorder are inherited from a male or female parent to a male or female child. Hemophilia A and C are mostly passed down from mother to son because of the passing down of the X chromosome. Many daughters who receive it are just carriers. Hemophilia C can be from either parent and go to either child.
Symptoms of hemophilia vary on the type of this disorder and the level it is at. Some of the symptoms can be mild and not really affect the victim. Others may experience severe bleeding that might be life threatening. Some symptoms include, bruising, swelling, a lot of bleeding, or random nosebleeds. Other results can be tight joints, blood in urine, or unusual bleeding after shots. Severe symptoms are, headaches, neck pain, sudden pain in joints, endless vomiting , or double vision.
Treatments for hemophilia may be regular shots of DDAVP or clotting factor. This would just be daily medical infusion that would help blood clotting. The patient could also take blood clotting medicine or fibrin sealants that are placed on a wound or injury. Other treatments could be physical therapy or vaccinations. Options vary on which type of hemophilia a person has and on what level the disorder is.
A possible future cure for hemophilia may not be so far away. There have already been experiments with this option and so far it has worked. This possible cure of the disorder is called gene therapy. A person with hemophilia can have certain cells taken out, depending on the factor of the disorder. Then, new genetic material can be inserted and in these cells, and placed back where they were. This new genetic material can tell the cells to produce for the factor of the disorder. This will get rid of the hemophilia and the symptoms will stop.
The positive implications of this technology are that it will stop symptoms for those that are struggling with hemophilia. It has already been tested and has had a positive result so far. However, only animal tests have been completed and very few humans with positive outcomes. These tests have also not been determined on how long the treatment will last. The tests have not backfired so far but the possibility always stands.
In conclusion, hemophilia is a genetic disorder that has been passed down and affected many humans over the years. Although some of the symptoms may be mild, there are many cases in which the disorder is life threatening. The possible issue of internal bleeding may put the person’s life in danger. However, with future technology, a possible cure may come. There are current tests for the cure of hemophilia and and results are showing that the end may not be far.