Fecal Transplant Essay

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Fecal Transplant: Is It Effective for Ulcerative Colitis Is fecal microbiota transplant (FMT) effective treatment for patients with Ulcerative Colitis (UC). UC is a chronic inflammation of the large intestine. FMT is used to describe the delivery of a healthy donors stool into a patient via enema, colonoscope, or nasogastric tube. In the past several years FMT has been used for an alternative treatment with patients diagnosed with Clostridium difficile (CD). The purpose of this paper is to discuss if FMT is just as effective in treating UC over just medication. The articles below will give insight if this theory is true or not. The First Documented Fecal Transplant An article published in Lancet in 1989 by Bennet and Brinkman, reported the first use of FMT for treatment of Irritable Bowel Disorder. Bennet was diagnosed with UC himself and performed a trial of self-transplanted donor stool by retention enema. He would take the stool and reconstitute it with saline in order to be administered through an enema. Three months later colon biopsies showed improvement in inflammation and he remained symptom free for six months (Clinical and Experimental Gastroenterology, 2015). There …show more content…

Pediatric patients, usually teenagers can be emotionally changing, between school, sports, and not to mention isolation from peers due to not understanding the disease process itself. An article published on January 2015, in the JPGN magazine, discusses four pediatric boys with moderate symptoms undergone FMT via a nasogastric tube. Prior to FMT, each boy was given rifaximin daily for 3 days and 17 g of Miralax in 8oz of water 3 times a day for 2 days prior to FMT. Evaluations on all four patients were done at 2, 6, and 12 weeks after FMT. None of the four patients showed any significant improvement with FMT nor changes in stool value (JPGN, 2015). This study didn’t have any more trials

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