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The history of necrosis in Dupuytren's disease
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A person looks at his hand; the palm facing up and forms his hand into a claw. He pays particular attention to his fingers and the feel of the tendons, ligaments, and muscles as he forms a claw. He imagines that this is happening to him over time. He has no control over it and cannot stop it. Unlike people with Dupuytren’s disease, he can straighten out his hands. I struggle with Dupuytren’s condition in both of my hands.
In order to empathize with the struggles of a Dupuytren’s patient, people need to be informed about the disease. It is important to understand the diagnosis, treatment, outcomes, and history of the condition that leaves people with malformed hands.
“Dupuytren’s contracture originated with the Vikings, who spread it throughout Northern Europe and beyond” as they plundered, raped, settled, and intermarried (Flatt). Dr. Charles Eaton, a member of the board of trustees of the Dupuytren’s Foundation, indicates that although “it’s been described as a Viking or Scotch-Irish disease,” Dupuytren’s condition is found in people of European descent wherever they originated on the continent (Eaton). Millions of people suffer from the disease today. However, the condition was reported by Guillaume Dupuytren in 1831. “Getting to Grips with Celtic Hand”).
Baron Guillaume Dupuytren, French anatomist and military surgeon is best known today for his treatment Dupuytren’s disease. He performed the first corrective surgery in 1831 (“Sticky Finger”).
Treatments such as surgery benefit 27 million patients in the United States and Europe. Famous people who have suffered from Dupuytren’s condition include playwright Samuel Beckett, actor David McCallum, President Ronald Reagan, an...
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...Aponeurotomy (Needle Fasciotomy).” Dupuytren contracture Institute. N.p., n.d. Web. 13 Mar. 2014.
Eaton, Charles M. Personal interview. 10 Feb. 2014.
Flatt, Adrian E. “The Vikings and Baron Dupuytren’s Disease.” US National Library of Medicine. N.p., n.d. Web. 9 Mar. 2014.
“Getting to Grips with Celtic Hand.” philipgrieve.com N.p., n.d. Web. 14 Mar. 2014.
“Managing Dupuytren’s contracture .” Everyday Health. N.p., n.d. Web. 12 Mar. 2014
Figure 1. Stages Of Dupuytrens Contracture. "Dupuytren’s Contracture: Playing The Hand You’re Dealt." Yogo Tune Up Blog. N.p., n.d. Web. 15 Mar. 2014.
“Sticky Finger.” The Register Guard. N.p., n.d. Web. 9 Mar. 2014.
Trojian, Thomas H., and Stephianie M. Chu. "Dupuytrens Diease: Diagnosis and
treatment." American Family Physician. N.p., n.d. Web. 14 Mar. 2014.
2. At age 4, James underwent a biopsy of the right gastrocnemius muscle. The pathologist's report noted histopathologic changes suggestive of Duchenne muscular dystrophy. Describe in detail the typical microscopic changes noted in the muscle tissue of someone with Duchenne's muscular dystrophy.
The Beauty of Bodysnatching written by Burch Druin is a fascinating biography of Astley Cooper, an English Surgeon, and Anatomist, who gained worldwide fame in support of his contribution to Vascular Surgery and a further area of expertise. The extract gives a reflective insight into Cooper’s contribution to study of Anatomy and medicine. Cooper enjoyed the job of body snatching, which helped him to conduct a series of discoveries that were important for the future study and understanding of Physiology. In the Romantic era, when prettiness or horror was a sensitive matter and extensive concern at that time many physicians discouraged surgery, but Cooper passionately practiced it.
Hutchinson, Tom “Illness and the hero’s journey: still ourselves and more”, CMAJ. 162.11 (2000):p.1597 web (date accessed).
"Duchenne Muscular Dystrophy: MedlinePlus Medical Encyclopedia." U.S National Library of Medicine. U.S. National Library of Medicine. Web. 20 May 2014.
Snider, Robert K. "Dupuytren's Disease." Essentials of Musculoskeletal Care. Rosemont, IL: American Academy of Orthopaedic Surgeons, 1997. 198-99. Print
Christopher Hamlin, “Edwin Chadwick, ‘Mutton Medicine’, and the Fever Question,” Bulletin of the History of Medicine 70 (1996): 233-265.
Walton, Sir John. Brain's Diseases of the Nervous System. Oxford University Press. New York, 1955, pp. 365.
and European society scrambled to find a cure to this mysterious disease. This study ponders the effects of medieval methods of treatment on this once ravaging disease.
Until a cure is found 1 in approximately every 3,500 boys will inherit Duchenne muscular dystrophy and eventually die from it. The current treatments only place a temporary obstacle in front of the disease. It is hoped that advancements in the fields of science and medicine will help to speed along the discovery of a cure for this debilitating muscular disease.
Rush, Benjamin. Medical Inquiries and Observations, upon the Diseases of the Mind. Diss. Philadelphia: Kimber and Richardson, 1812. Print.
Bushby RF, Birnkrant DJ, Case LE, Clemens PR, Cripe L, Kaul a, et.al Diagnosis and management of Duchenne Muscular Dystrophy. Lancet Neurol. 2010;9:77-93.(PubMed:19945913)
It is estimated that 1 out of every 5,600-7,700 boys ages 5-24 have Duchene or Becker muscular dystrophy. (“Data & Statistics,” 2012 April 6) Muscular dystrophy is a group of genetic diseases defined by muscle fibers that are unusually susceptible to damage. There are several different types of muscular dystrophy some of which shorten the affected person’s lifespan. (“Muscular dystrophy: Types and Causes of each form,” n.d.) There is a long history of the disorder but until recently there wasn’t much knowledge of the cause. (“Muscular Dystrophy: Hope through Research,” 16 April 2014) Symptoms are obvious and can be seen as soon as a child starts walking. (“Muscular Dystrophy,” 2012 January 19) Although muscular dystrophy mostly affects boys, girls can get it too. (“Muscular Dystrophy,” 2012 January 19) There is no cure for muscular dystrophy but there are several types of therapy and most types of muscular dystrophy are still fatal. (“Muscular Dystrophy: Hope through Research,” 16 April 2014)
Vorvick, Linda, Jatin Vyas and David Zieve. "Gangrene." 24 August 2011. MedLine Plus. 20 November 2013 .
Bratton, R. L., Whiteside, J. W., Hovan, M. J., Engle, R. L., Edwards, F. D. (2008). Diagnosis
Weston, M. D. Know Your Body: The Atlas of Anatomy. Berkeley, CA: Marshall Cavendish Books Limited, 2005