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Role of biomedical engineers essay
Role of biomedical engineers essay
Role of biomedical engineers essay
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Suppose you are at the hospital and notice a patient sitting outside his doctor’s office. The painful expression on his face shows that he had just received dreadful news. His doctor had informed that the HIV virus that was present in his cells had mutated into AIDS and his life is in serious danger. There is one procedure that could perhaps save his life. However, this method has never been tested on humans. This operation involves nanoparticles killing the virus and saving the man’s life. Biomedical engineers who discovered this process are convinced that this process can be extremely painful for the patient since the patient is not allowed to be under anesthesia. Nevertheless, doctor’s are not assured whether the treatment could save or …show more content…
With the goal of improving the quality and effectiveness of patient care, biomedical engineers design instruments, devices, and software. In spite of the power biomedical engineers carry, they are also left with a mountain of challenges. To overcome to the problem plenty of biomedical engineers are faced with today, Robert Langer, an American engineer and an Institute Professor at the Massachusetts Institute of Technology, stated that certain methods are unacceptable owing to the fact that they are inhumane. Langer and his team were working on polymers that could deliver DNA as efficiently as viruses. The only problem with this procedure was that the viruses may have dangerous side effects and have been responsible for deaths in some gene-therapy trials. “So far, the problem has been that such "synthetic vectors" have been far less efficient in carrying out the delivery,” Langer states, “But in early tests. . . some polymers have been as effective at delivering the DNA strands to their target as the viruses, but with 100 times less toxicity” (Par. 9). Langer and his team were able to maneuver different techniques to avoid undesirable procedures so they may be tolerable to the
The fact that there have been many advancements in biomedical technology over the years have given us the ability to cure and prevent diseases that have once devastated the human population. These breakthroughs have allowed people to live longer and healthier lives, yet others believe that it runs the risk of “playing God” and that such matters should be left into the hands of a higher power. Today, this ethical debate still continues to raise questions on whether these scientific breakthroughs are morally acceptable. While I support the use of scientific breakthroughs, I believe that it should only be used for human benefit to cure those who are suffering from cancer. This approach seems more reasonable than using this technology to choose one’s eye color or keep someone on life support just because it is something that can be done, whether or not that is acceptable or not.
There has been some ethical issues surrounding the development and use of technology, that would consist of some advancements, such as “when in vitro fertilization is applied in medical practice and leads to the production of spare embryos, the moral question is what to do with these embryos” (Shi & Singh, 2008, p. 182). As for ethical dilemmas that comes into play with “gene mapping of humans, genetic cloning, stem cell research, and others areas of growing interest to scientist” (Shi & Singh, 2008, p. 182). “Life support technology raises serious ethical issues, especially in medical decisions regarding continuation or cessation of mechanical support, particularly when a patient exists in a permanent vegetative state” (Shi & Singh, 2008, p. 182). Health care budgets are limited throughout this world, making it hard for advancements yet even harder to develop the advancements with restraints. Which brings us back to the “social, ethical, and legal constraints, public and private insurers face the problem deciding whether or not to cover novel treatments” 188. Similarly what was mentioned before the decisions about “new reproductive techniques such as intracytoplasmic sperm injection in vitro fertilization (ICSIIVF), new molecular genetics predictive tests for hereditary breast cancer, and the newer drugs such as sildenafil (Viagra) for sexual dysfunction” (Giacomini, 2005).
Based off of these findings, much advancement in medicine has been created to improve life. The most common today is the cure for certain viruses. By simply taking a shot containing a vaccine, that took extensive research and self-intuition, one can dramatically reduce their chance of the virus affecting them later on.
... fight the disease. It is crucial that regulation be a necessary component of gene therapy research and applications. In hopes that the government can regulate and can receive this treatment, not restricting it to people that has serious genetic diseases. Gene therapy will change the field of medicine from what it is today. As scientist discovers more genes and their functions, the potential of this treatment is limitless. Though gene therapy is an auspicious treatment choice for numerous diseases (including inherited disorders, some types of cancer, and certain viral infections), the procedure remains precarious and is still under study to make sure that it will be safe and effective. Thus government regulators and scientist must take a lead role in adopting a practical approach to address these issues and determining the correct procedures for dealing with them.
Imagine that there is a cure for nearly every ailment that affects the human race. Imagine that you could help the terminally ill, put those you love out of pain, and cut the healing time of an enormous number of serious illnesses in half. Imagine a world in which pain and suffering would be nearly nonexistent, and the people you love can live safe from the fear of crippling injury. Now what if I told you that this utopia was a fast approaching reality? Everything from serious life threatening burns to lymphoma, AIDS, Alzheimer’s, Muscular Dystrophy, Parkinson’s Disease, Spinal Cord Injury, and Strokes could, in the very near future, be eliminated through the simple culturing and implementation of stem cell therapy . These diseases are no small component of the myriad of conditions that plagues the human race, and yet, the end for these horrible maladies could very well be in sight. Man has always sought to end suffering, largely without success, until now. the promise that stem cell therapy holds could completely change our world for the better. Already, stem cell therapy is being used to treat leukemia, immune disorders, hodgkins and non-hodgkins lymphoma, anemia and a profusion of other ailments. As you all know, this is no small accomplishment. One day i believe that we may look at alzheimer's and diabetes and other major illnesses much like we look at polio today, as a treatable illness. Right now, our research with stem cells is providing us with new light into how we look at and model disease, our ability to understand why we get sick and even to develop new drugs. In 2008, a researcher from the New York Stem Cell Foundation Laborato...
Gene therapy, a relatively new innovention, is becoming popular across the country. Gene therapy modifies a part of an organism, whereas cloning creates an entirely recreated organism. This technique can be conducted in vivo in either somatic or germ cells. The process is essentially aimed at fixing a genetic disorder or disease by inserting a functional gene to replace the faulty one (Houdebine 2003). Many methods to conduct a gene transfer have been tested. The two types are in vivo and in vitro. Transferring genes in vivo means placing the functional genes directly into the target tissue; while vitro transfers creates the genes outside of the body, in Petri dishes. Vitro is an expensive process that r...
In September 14, 1990, an operation, which is called gene therapy, was performed successfully at the National Institutes of Health in the United States. The operation was only a temporary success because many problems have emerged since then. Gene therapy is a remedy that introduces genes to target cells and replaces defective genes in order to cure the diseases which cannot be cured by traditional medicines. Although gene therapy gives someone who is born with a genetic disease or who suffers cancer a permanent chance of being cured, it is high-risk and sometimes unethical because the failure rate is extremely high and issues like how “good” and “bad” uses of gene therapy can be distinguished still haven’t been answered satisfactorily.
Over 20 years after the proclamation of these specific ethical guidelines, we are introduced to the University of Pennsylvania’s Institute for Human Gene Therapy’s study on a delivery mechanism for gene therapy that resulted in the death of an 18 year old research subject Jesse Gelsinger. Gelsinger suffered from partial OTC (ornithine transcarbamylase) deficiency caused by a defective single gene (Obasogie, 2009).
Many people around the world today suffer from many forms of disease, and handicaps. From cancer and tumors; to total paralysis and AIDS. Medicine and technology as so far advanced, that many many patients that contract ailments that were once considered a death penalty, now face new hope. While such things as AIDS, and paralysis are not curable, people can be assured a longer, and possibly happier life than they would have a few decades ago; but...
Although humans have altered the genomes of species for thousands of years through artificial selection and other non-scientific means, the field of genetic engineering as we now know it did not begin until 1944 when DNA was first identified as the carrier of genetic information by Oswald Avery Colin McLeod and Maclyn McCarty (Stem Cell Research). In the following decades two more important discoveries occurred, first the 1953 discovery of the structure of DNA, by Watson and Crick, and next the 1973 discovery by Cohen and Boyer of a recombinant DNA technique which allowed the successful transfer of DNA into another organism. A year later Rudolf Jaenisch created the world’s first transgenic animal by introducing foreign DNA into a mouse embryo, an experiment that would set the stage for modern genetic engineering (Stem Cell Research). The commercialization of genetic engineering began largely in 1976 wh...
Many great inventions have been made through research in biomedical engineering, for example, genetic engineering, cloning, and insulin. After insulin has been invented, there are still a lot of problems with the purity and the quantity of the insulin produced. Biomedical engineering devised a way to produce large quantities of insulin with a higher level of purity, which has saved a lot of human lives. Although biomedical engineering just been officially founded 200 years ago, its practice has been with us for centuries. According to The Whitaker Foundation website, 3,000-year-old mummy from Thebes, which uncovered by German archeologists, with a wooden prosthetic tied to its foot to serve as a big toe is the oldest known limb prosthesis and Egyptian listen to the internal of human anatomy using a hollow reed, which is what today’s stethoscope. No matter what the date, biomedical engineering has provided advances in medical technology to improve human health. These advances by biomedical engineering have created a significant impact to our lives. I have determined to become a biomedical engineer. Biomedical engineering will have a good prospect because it will become one of the most important careers in the future.
The birth of genetic engineering and recombinant DNA began in Stanford University, in the year 1970 (Hein). Biochemistry and medicine researchers were pursuing separate research pathways, yet these pathways converged to form what is now known as biotechnology (Hein). The biochemistry department was, at the time, focusing on an animal virus, and found a method of slicing DNA so cleanly that it would reform and go on to infect other cells. (Hein) The medical department focused on bacteria and developed a microscopic molecular messenger, that could not only carry a foreign “blueprint”, or message, but could also get the bacteria to read and copy the information. (Hein) One concept is needed to understand what happened at Stanford: how a bacterial “factory” turns “on” or “off”. (Hein) When a cell is dividing or producing a protein, it uses promoters (“on switches”) to start the process and terminators (“off switches”) to stop the process. (Hein) To form proteins, promoters and terminators are used to tell where the protein begins and where it ends. (Hein) In 1972 Herbert Boyer, a biochemist, provided Stanford with a bacterial enzyme called Eco R1. (Hein) This enzyme is used by bacteria to defend themselves against bacteriophages, or bacterial viruses. (Hein) The biochemistry department used this enzyme as a “molecular scalpel”, to cut a monkey virus called SV40. (Hein) What the Stanford researchers observed was that, when they did this, the virus reformed at the cleaved site in a circular manner. It later went on to infect other cells as if nothing had happened. (Hein) This proved that EcoR1 could cut the bonding sites on two different DNA strands, which could be combined using the “sticky ends” at the sites. (Hein). The contribution towards genetic engineering from the biochemistry department was the observations of EcoR1’s cleavage of
One of the biggest concerns involved in gene therapy in humans is the lack of knowledge and the possibility for consequences later on or i...
Human technology is constantly evolving, and with it society and medicine must follow suit. Every year, new breakthroughs in the field of medicine award mankind with a few more years of immortality. Scientists are constantly working to solve problems that once posed the threat of imminent death. Over two hundred years ago, the vaccine for Smallpox—one of the world’s deadliest killers—was discovered in 1796 (“CDC”). Since then, humans have been steadily eradicating every threat to individual health. Only last month, December of 2011, researchers from the University of Western Ontario revealed a new HIV vaccine that has been approved for human te...
The procedures that will be the future of modern medicine currently fall into the realms of taboo and fictional. These procedures encompass every aspect of medical science, from exploration of the human body, curing diseases, to improving a person’s quality of life. Many of these procedures are not very well known, while a few have been in the spotlight. These procedures include cloning, nano-robotics, retro-viruses, and genetic manipulation via gene-specific medications. For any serious breakthroughs in modern medical science, we must embrace these new forms of treatment instead of shying away from them. Second, I’ll attempt to explain how these methods and procedures could benefit mankind.