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The effects of blood glucose on diabetic and non diabetic people
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Diabetic Vascular Disease is a disorder of metabolism and is one of many diseases that can affect the heart and the system surrounding it. The food we eat is broken down into a substance known as Glucose which is the body’s most important and main source of food that is given to the body to provide energy for cells. However, for this substance to work properly and appropriately, a hormone called insulin must be present in the body. “Diabetes develops when the pancreas does not provide and make enough insulin or the cell in the muscles, liver, and fat do not use insulin properly. As a result, the amount of glucose in the blood increases while the cells are starved of energy.” (National Institute of Diabetes and Digestive and Kidney Diseases,
Glucose is a sugar that plays a big part in a human’s health and well-being. This sugar is a major source of energy for the body’s brain and cells. The Cells that receive energy from glucose help in the building of the body’s muscle and tissue. Although glucose may be important to the body too much of this sugar can cause a chronic condition called Diabetes. Diabetes, also known as Diabetes mellitus, is a chronic condition that is caused by too much sugar in the blood. This condition can affect all age groups. In fact, in 2010 a survey was taken by the National Diabetes Information Clearinghouse, on the number of newly diagnosed diabetes. Out of 1,907,000 people: 24.38% were ages 20-44, 55.17% were ages 45-64, and 20.45% were ages 65 and greater. Diabetes is a very serious condition, and it can be deadly if left untreated. This paper will help better educate the reader on the signs and symptoms, the testing process, and the management of diabetes.
The pathophysiology of diabetes mellitus in is related to the insulin hormone. Insulin is secreted by cells in the pancreas and is responsible for regulating the level of glucose in the bloodstream. It also aids the body in breaking down the glucose to be used as energy. When someone suffers from diabetes, however, the body does not break down the glucose in the blood as a result of abnormal insulin metabolism. When there are elevated levels of glucose in the blood, it is known as hyperglycemia. If the levels continue to remain high over an extended period of time, damage can be done to the kidneys, cardiovascular systems; you can get eye disorders, or even cause nerve damage. When the glucose levels are low in one’s body, it is called hypoglycemia. A person begins to feel very jittery, and possibly dizzy. If that occurs over a period of time, the person can possibly faint. Diabetes mellitus occurs in three different forms - type 1, type 2, and gestational.
Throughout the whole of the United Kingdom, between 2 and 3 of every 100 people have a known form of diabetes (DTC, 2004). What is diabetes? Explained simply, it is a disease in which the body does not produce or properly use insulin. In the normal state of glucose function, there is a stable release and uptake of glucose, regulated by two hormones produced in the pancreas, glucagon and insulin. There are two distinct mechanisms which give rise to the abnormal blood glucose levels seen in patients with type I and type II diabetes. In type I diabetes, a deficiency in insulin production at the pancreas results in elevated blood glucose levels due to the lack of hormonal regulation. In type II diabetes, although the pancreas produces regular levels of insulin, the body resists the effect of insulin, inhibiting the ability of insulin to break down glucose in the blood. Because of the inherent differences in the biochemical mechanisms of these two diseases, the characteristics associated with type I and type II diabetes are very different. The typical onset of type I diabetes is usually ...
Diabetes is a disease in which a person’s body in unable to make or utilize insulin properly which affects blood sugar levels. Insulin is a hormone that is produced in the pancreas, which helps to regulate glucose (sugar) levels, break down carbohydrates and fats, and is essential to produce the body’s energy. The CDC (2013) offers reliable insight, summarized here, into the different types of diabetes, some causes, and health complications that may arise from the disease.
The purpose of this study is to research the disease Type 2 Diabetes and to discover whether it is being effectively treated and prevented in Merced County, California. According to the National Institutes of Health, Diabetes Mellitus is “a lifelong (chronic) disease in which there are high levels of sugar (glucose) in the blood. It is also the most common form of Diabetes”.1 Furthermore, there are many risk and lifestyle factors associated with this disease, but the most prevalent are; obesity (#1 risk factor), sedentary lifestyle, unhealthy eating habits, family history and genetics, increased age, high blood pressure and high cholesterol, and a history of gestational diabetes.2 The long term complications of having type 2 diabetes can include but are not limited to; eye problems (cataracts and glaucoma), foot problems (neuropathy/ nerve damage), skin problems (infections), high blood pressure (which raises your risk for heart attack, stroke, eye problems and kidney disease), hearing loss, oral health, mental health and early death.3
Diabetes is one of the most common diseases that almost every family is suffering these days with one or more family members globally. But most people are still unaware the causes, symptoms and treatment of diabetes. Diabetes, in a simple language, is directly related to our digestion system. Whatever we eat, we need to digest and for digestion our food breaks into small pieces of glucose or sugar. This sugar then goes to our blood cells and gives us energy to work for the day. Now to transfer glucose to our blood cells, we need insulin that is made by pancreas. If due to some reasons, our pancreas is not able to produce enough amount of insulin to transfer glucose into the blood cells, the condition is known as diabetes, and the person suffering from this disease is called as a diabetic.
Diabetes refers to a set of several different diseases. It is a serious health problem throughout the world and fourth leading cause of death by disease in the country. All types of diabetes result in too much sugar, or glucos in the blood. To understand why this happens it would helpful if we understand how the body usually works. When we eat, our body breaks down the food into simpler forms such as glucose. The glucose goes into the bloodstream, where it then travels to all the cells in your body. The cells use the glucose for energy. Insulin, a hormone made by the pancreas, helps move the glucose from bloodstream to the cells. The pathophysiology of diabetes mellitus further explains the concept on how this disease works. Pancreas plays an important role of the metabolism of glucose by means of secreting the hormones insulin and glucagon. These hormones where then secreted by Islets of Langerhans directly to the blood. Inadequate secretion of insulin results on impaired metabolism of glucose, carbohydrates, proteins and fats which then result to hyperglycemia and glycosuria. Hyperglycemia is the most frequently observed sign of diabetes and is considered the etiologic source of diabetic complications both in the body and in the eye. On the other hand, glucagon is the hormone that opposes the act of insulin. It is secreted when blood glucose levels fall.
The website myclevelandclinic.org defines diabetes mellitus as a, "disease of the pancreas, an organ behind your stomach that produces the hormone insulin. Insulin helps the body use food for energy. When a person has diabetes, the pancreas either cannot produce enough insulin, uses the insulin incorrectly, or both. Insulin works together with glucose (sugar) in the bloodstream to help it enter the body's cells to be burned for energy. If the insulin isn't functioning properly, glucose cannot enter the cells. This causes glucose levels in the blood to rise, creating a condition of high blood sugar or diabetes, and leaving the cells without fuel."
Latent diabetic vascular complications are a hallmark of the disease and known to significantly affect the cardiovascular and renal systems. Atherosclerosis is the main reason for decreased life expectancy in patients with diabetes, whereas diabetic nephropathy and retinopathy are the largest contributors to end-stage renal disease and blindness, respectively (37, 56). Current therapy is aimed at managing blood glucose concentrations and increasing insulin resistance. Thus, vascular complication mitigation includes: blood glucose monitoring and lowering, which decreases the risk of nephropathy and retinopathy. Antihypertensive medicine is also utilized to decrease the risk of cardiovascular disease, nephropathy, and retinopathy (15, 26). As well, hypertension is closely associated with stroke and pulmonary edema. Despite these advances, diabetes complications and their treatments are aimed at abating symptoms in an effort to improve physiological function.
Now that we have a general idea of how our body regulates sugar intake we can discuss exactly what diabetes is. It is a disease in which your body is unable to use glucose for energy, resulting in elevated blood glucose levels. There are a few different types of diabetes. In some cases, a person’s body does not make insulin at all. Thus, there is no insulin to tell your cells to use the glucose for energy. This is called type 1 diabetes, or it was previously known as juvenile diabetes. Only 5 to 10% of diabetes cases are diagnosed as type 1 (Grosvenor & Smolin, 93). It is usually discovered before a pers...
Ischemic Heart Disease, also known as Coronary Artery Disease, is a condition that affects the supply of blood to the heart. Coronary artery disease may show no signs of symptoms, or chest pain before you know heart attack. The blood vessels are narrowed or blocked due to the deposition of cholesterol on their walls. This reduces the supply of oxygen and nutrients to the heart muscles, which is essential for proper functioning of the heart. This may eventually result in a portion of the heart being suddenly deprived of its blood supply leading to the death of that area of heart tissue, resulting in a heart attack. The cardiovascular issue has been a big problem for people who
PAD occurs when atherosclerosis is found in arteries that perfuse the limbs, particularly the lower extremities. Atherosclerosis is thickening and hardening of the vessel wall caused by an accumulation of lipid-laden macrophages inside the arterial wall, which causes the formation of lesions or plaques. This process begins when the endothelial cells that line the artery walls are damaged. This lesion progresses from endothelial injury and dysfunction to fatty streaks to fibrotic plaques and ending in a complete lesions. Endothelial damage can be caused by a variety of factors including; smoking hypertension, diabetes, increased levels of low-density lipoprotein (LDL) and high-density lipoprotein (HDL), and autoimmunity. Atherosclerosis
Insulin is produced in the pancreas, inside the pancreas are pancreatic islets cells which secrete the insulin. Pancreatic islets are also known as islets of langerhans, they are clumps of cells scattered among the pancreatic cells. This hormone is known to be produced by the beta cells of the pancreatic islets. Blood glucose is also known as blood sugars, these blood sugars are required to be at a normal (80-100 mg of sugar) level. Hyposecretion can cause type 1 diabetes mellitus, which means that not enough blood glucose is not leaving the blood. The hyposecretion is caused by many factors like tumors in the pancreas. Type 2 diabetes is caused by the failure of the insulin receptors not being able to send the message to the cell to produce
Diabetes mellitus is a group of metabolic disorders which is characterized by hyperglycemia due to insulin deficiency or resistance or both reasons. (1) According to that diabetes mellitus can be divided as type I and type II. This is common and its incidence is rising, 171 million people had diabetes in 2000 it is expected this condition to be doubled in 2030. It is spread in all the countries and therefore has become a major burden upon healthcare facilities. (2)
Diabetes Mellitus is a disease in which the pancreas produces little or no insulin. Insulin is a hormone that helps the body’s tissues absorb glucose which is sugar, so it can be used as a source of energy. Glucose levels build up in the blood and urine which causes excessive urination, thirst, hunger, and problems with fat and protein metabolism in a diabetic person. Diabetes is very common in the United States; it is the seventh leading cause of all deaths. Women have been diagnosed with diabetes more than men. There are two forms of diabetes, Type one and Type two diabetes. Type one diabetes is when the body does not produce insulin or produces it in very small quantities. This usually occurs in younger people under twenty years of age, mostly around puberty. Type two diabetes is when the body’s balance between insulin production and the ability of cells to use insulin doesn’t work properly. This is more common than type one; about 90-95% people in the United States have it. There are no cures for diabetes now but there are many researchers investigating factors through new technologies to cure them. Meanwhile, technological advancements are being made to keep glucose at a good level for diabetes.