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Recommended: The structure of dna
The origins of DNA were first discovered during 1857 by Gregor Mendel the "Father of Genetics”, whom was performing an experiment of genetics with pea plants, and would provide a basic foundation towards DNA and Genetics. Friedrich Miescher and Richard Altmann in 1869 were also part of the first people to discover DNA. While testing some sperm of a salmon, they discover a strange substance that they would name as "nuclein", which is known as DNA. This new form of "nuclein" (DNA) would be found to only exist in chromosomes. Frederick Griffith, a researcher, found the basis on DNA, from a molecule inheritance experiment involving mice and two types of pneumonia. His findings were that, when virulent disease is heated up (to kill) and is injected into a mouse, the mouse survives. Unlike the second mouse that has been injected with non-virulent disease and virulent disease (that had been heated and killed) is killed. This would be caused by an inheritance of molecule (transformation) of virulent bacteria passing on a characteristic to the non-virulent. DNA findings would continue to be tested and tried to better understand how DNA works.
Deoxyribo Nucleic Acid (DNA) is a chromosome found in the nucleus of a cell, which is a double-stranded helix (similar to a twisted ladder). DNA is made up of four bases called adenine (A), thymine (T), guanine (G), and cytosine (C), that is always based in pairs of A with T and G with C. The four bases of A, C, G, and T were discovered by Phoebus Levene in 1929, which linked it to the string of nucleotide units through phosphate-sugar-base (groups). As mention in Ananya Mandal research paper, Levene thought the chain connection with the bases is repeated in a fix order that make up the DNA molecu...
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...stody." TheFreeDictionary.com. N.p., n.d. Web. 10 Dec. 2013. <>.
Wikipedia contributors, . N.p.. Web. 10 Dec 2013. .
Norrgard, Karen. "Forensics, DNA Fingerprinting, and CODIS." Nature.com. Nature Publishing Group, n.d. Web. 010 Dec. 2013. .
Wittmeyer, Jacqui. "CAN DNA DEMAND A VERDICT?" Can DNA Demand a Verdict? University of Utah, n.d. Web. 08 Dec. 2013. .
"Forensic DNA Analysis." Marshall University Forensic Science Center. State of West Virginia, n.d. Web. 10 Dec. 2013. .
"Learn: DNA Profiling" Unit 3 Trace Evidence, Lesson 7 from SCI030: Forensic Science Course
Office of the Inspector General. (2010). Review of the Federal Bureau of Investigation Laboratory’s Forensic DNA Case Backlog. U.S. Department of Justice.
The analysis of the samples should be used only to confirm or negate match between the sample taken from the crime scene fgand the sample taken from the suspect. That is, it should sdfremain as an identifgication tool only. There should be no further analysis of the DNA to suggest psychological characteristics that would make the suspect more likely to have cdfommitted the crime. This rule should apply also to samples taken from convicted dfdoffenders for a data vor dagta bank.
In 1989 the National Research Council Committee on DNA Technology in Forensic Science was developed due to numerous scientific and legal issues (The Evaluation of Forensic DNA Evidence). The National Research Council’s key role was to analyze statistical and population genetic issues in the use of DNA evidence and review major alternative approaches to statistical evaluation of DNA evidence (The Evaluation of Forensic DNA, 50). Over the past fifteen years DNA profiling has made tremendous advancements and continuous improvements in the fight against violent
Nowadays, DNA is a crucial component of a crime scene investigation, used to both to identify perpetrators from crime scenes and to determine a suspect’s guilt or innocence (Butler, 2005). The method of constructing a distinctive “fingerprint” from an individual’s DNA was first described by Alec Jeffreys in 1985. He discovered regions of repetitions of nucleotides inherent in DNA strands that differed from person to person (now known as variable number of tandem repeats, or VNTRs), and developed a technique to adjust the length variation into a definitive identity marker (Butler, 2005). Since then, DNA fingerprinting has been refined to be an indispensible source of evidence, expanded into multiple methods befitting different types of DNA samples. One of the more controversial practices of DNA forensics is familial DNA searching, which takes partial, rather than exact, matches between crime scene DNA and DNA stored in a public database as possible leads for further examination and information about the suspect. Using familial DNA searching for investigative purposes is a reliable and advantageous method to convict criminals.
In April of 1953, James Watson and Francis Crick published a game changing paper. It would blow the mind of the scientific community and reshape the entire landscape of science. DNA, fully knows as Deoxyribonucleic Acid is the molecule that all genes are made of. Though it is a relatively new term with regard to the age of science, the story of DNA and the path to its discovery covers a much broader timeframe and had many more contributors than James Watson and Francis Crick. After reading the paper the audience should have a better understanding of what DNA is, the most important experiments that contributed to its ultimate discovery and the names and contributions of the lesser-known scientists that helped Watson and Crick turn their idea
accept DNA profiles from. As estimated by the FBI, the chances of two DNA samples
Tsou, J. A., Hagen, J. A., Carpenter, C. L., & Laird-Offringa, I. A. (2002, August 05). DNA
This paper examines Carrells et al’s research along with three other research articles to review how DNA is collected, the effects that is has on a juror and the pros and cons of DNA collection in the Forensic Science and Criminal Justice community. Keywords: deoxyribonucleic acid, United States
Before the 1980s, courts relied on testimony and eyewitness accounts as a main source of evidence. Notoriously unreliable, these techniques have since faded away to the stunning reliability of DNA forensics. In 1984, British geneticist Alec Jeffreys of the University of Leicester discovered an interesting new marker in the human genome. Most DNA information is the same in every human, but the junk code between genes is unique to every person. Junk DNA used for investigative purposes can be found in blood, saliva, perspiration, sexual fluid, skin tissue, bone marrow, dental pulp, and hair follicles (Butler, 2011). By analyzing this junk code, Jeffreys found certain sequences of 10 to 100 base pairs repeated multiple times. These tandem repeats are also the same for all people, but the number of repetitions is highly variable. Before this discovery, a drop of blood at a crime scene could only reveal a person’s blood type, plus a few proteins unique to certain people. Now DNA forensics can expose a person’s gender, race, susceptibility to diseases, and even propensity for high aggression or drug abuse (Butler, 2011). More importantly, the certainty of DNA evidence is extremely powerful in court. Astounded at this technology’s almost perfect accuracy, the FBI changed the name of its Serology Unit to the DNA Analysis Unit in 1988 when they began accepting requests for DNA comparisons (Using DNA to Solve Crimes, 2014).
The identification of a substance/phenomenon/condition(s) is the first step toward a new discovery or invention of substantial application (human or otherwise). In the light of this fact, the knowledge of the discovery of DNA is vital to appreciate the beauty of evolution of the events that led to the discovery of DNA. Unlike the common belief that DNA was discovered by the American biologist James Watson and English physicist Francis Crick, the genetic material was first identified by the Swiss physiological chemist Friedrich Miescher in the 1860s. He named them “nuclein”. While having an intention of separating and identifying the proteins present in the white blood cells, he discovered a material inside the white blood cells that were similar to proteins but having high phosphorus content. Sensing the importance of his findings, Miesher wrote “It seems probable to me that a whole family of such slightly varying phosphorous-containing substances will appear, as a group of nucleins, equivalent to proteins”. It was only in 1953, that Watson and Crick put together pieces of experimental information by various investigators to bring forth the three dimensional structure of DNA. Although, various improvisations and extensions have been brought forth to the Watson Crick model, but the four major propositions still remain the same :
...A. Maria, Ruth M. Robin. (2009). Latent prints: a perspective on the state of the science. Forensic Science Communications. 11.4.
The scientific and medical progress of DNA as been emense, from involving the identification of our genes that trigger major diseases or the creation and manufacture of drugs to treat these diseases. DNA has many significant uses to society, health and culture of today. One important area of DNA research is that used for genetic and medical research. Our abi...
While DNA profiles can be obtained from evidentiary swabs, forensic science is currently deficient in the methods to determine the tissue source of the DNA. While proper confirmatory tests exist for biological fluids such as semen1,2 and blood3, similar tests for the confirmatory identification of saliva are lacking. Being able to confidently identify the source material of the DNA may help criminal investigators corroborate the claims of an alleged victim or suspect. For example, analysis of an evidentiary swab from an alleged suspects finger. The alleged victim states that she was sexual assaulted and the suspect used his finger to penetrate her. The alleged suspect states that no sexual assault occurred and that the alleged victim licked his finger at a bar. In this case, and many similar cases, being able to determine the source of the DNA would be critical in being able to solve the case.
Gaensslen, R. E., Harris, H A., & Lee, H. (2008). Introduction to Forensic Science and Criminalistics. New York, NY: The McGraw-Hill Companies, Inc. .
The amazing world of forensic science can help one to understand how important the methods of fingerprinting and blood testing is. For the past decade, a powerful criminal justice tool and topic referred as forensic DNA and fingerprinting has cleared suspects, exonerated individuals wrongfully accused or convicted criminals of a crime (Saferstein, 2015). DNA has been admitted into court for judges and juries to consider the scientific evidence when hearing a case. In the case of Cupp v. Murphy, the warrantless search of the scraping of blood from the fingernail of an accused murderer was upheld by the Supreme Court. It involved no medical risk nor the risk of destruction of the evidence or the suspect. It allowed forensic science to prove