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Cirrhosis of liver practical questions
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The liver is the largest organ in the body. It has many important and vital functions. Therefore, it must be healthy in order for someone to survive. A liver detoxifies the substances that are harmful in the body, makes sure the blood is purified and produces nutrients that are very important. When the liver is not able to function properly and starts to deteriorate this is known as a condition called Cirrhosis. The healthy liver tissue is replaced with scar tissue and the blood flow throughout the liver becomes blocked. When the healthy tissue is replaced with scar tissue, the liver will shrink. The liver can repair itself and function properly if the Cirrhosis is mild, but if the Cirrhosis slowly develops over the years, the liver …show more content…
will stop functioning. There are many causes for Cirrhosis. The main ones are alcohol, hepatitis B and C, and fatty liver disease. (Nordqvist,Christian ) There are usually not any symptoms of Cirrhosis in the early stages, but your liver will swell.
After a matter of time you will begin to notice some symptoms. The most common symptoms are: weakness, fatigue, loss of appetite, weight loss, yellowing of the skin, itchy skin, ascites, bleeding, bruising, and mental health changes. (Kenny, Tim ) Cirrhosis can also cause complications to other areas of the body. Ascites is fluid that is present on the inside cavity of the abdomen. Cirrhosis can cause the fluid to build up between the layers of the abdomen and make it become enlarged. Portal Hypertension is also caused by having cirrhosis. The blood flow slows down in the major blood vessel and creates pressure on the inside of the vein. The blood then returns to the heart by different blood vessels. When this happens, the increased blood flowing through these vessels become swollen causing varices. The varices can be easily broken because of the high blood pressure flow and could ultimately cause death. Also, when the liver is unable to remove toxins from the blood, the loss of brain function can occur. This is called Hepatic Encephalopathy. This occurs when the liver does not detoxify and breakdown body substances and the toxins build up in the bloodstream. Sedatives and narcotics can make Encephalopathy worse, so liver disease patients are not allowed to take these medicines. (Liver Anatomy …show more content…
) Cirrhosis will get worse if not treated.
Scarring is not reversible once the damage has already happened. Treating the underlying causes may stop or slow down Cirrhosis progression. Treatments may include medication, lifestyle change to help with weight loss, or an alcohol program, if alcohol related. Hypertension that is caused by Cirrhosis can be treated by a procedure called Transjuglar Intrahepatic Portosystemic Shunt. A fluoroscopy procedure is used to place a small stent to open the blood flow throughout the liver. If Cirrhosis is severe, surgery may be required to perform a liver transplant. The damaged liver will be replaced with a healthy one from a donor. (Cirrhosis of the Liver
) Diagnostic radiology is an important part of finding and treating Cirrhosis of the liver, in addition to blood tests and biopsies. If Cirrhosis is suspected, several imaging tests can be completed by your doctor. One of the imaging tests that could be used is the Abdominal ultrasound imaging that uses sound waves to create images of the liver, including the inside of the pelvis and/or abdomen. Another type of imaging used is the Abdominal Computed Tomography (CT) scan and it produces several images of the liver using special x-ray equipment with computers. It can also determine how serious the Cirrhosis is. Also, a body Magnetic Resonance Imagery (MRI) could detect liver problems by using radio frequency pulses, a powerful magnetic field and computers to create images of the liver that are very detailed. The damage is able to be assessed by the different liver diseases. In addition, a Magnetic Resonance Cholangiopancreatography (MRCP) can be used if needed. It is a special MRI that creates detailed images of the ducts for the liver and gallbladder. This MRI helps to assess any abnormalities. (Cirrhosis of the Liver )
This case study is about Abdul Chidiac, a 51 year old male, married with 4 children. He had a medical history of hypertension, hypercholesterolaemia and cirrhosis with two admissions in the last six months. He is a smoker and drinks beer, 5-6 bottles per day. As Carithers & McClain (2010) explained the patient’s medical history is another indicator of the risk for cirrhosis; the progression to cirrhosis is adaptable and may take time over weeks or many years. Cirrhosis is a liver disease characterized by permanent scarring of the liver that interferes with its normal functions including alcoholism. Most people who drink large amounts of alcohol cause harm to the liver in some way (Heidelbaugh & Bruderly, 2006). The cause of cirrhosis is not yet known, but the connection between cirrhosis and excessive alcohol ingestion is established (Jenkins & Johnson, 2010). Common causes of cirrhosis include: alcohol abuse, hepatitis B infection, hepatitis C infection and non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (Schuppan & Afdhal, 2008).
Hepatitis A is a usually short acting virus that occurs in humans and monkeys. It is caused by the Hepatovirus and the species is Hepatitis A Virus. There are two major ways in which Hepatitis A can be transmitted. One way is from person to person. This transmission occurs when the fecal matter of an infected person gets ingested by another person. Other ways Hepatitis A can be transmitted from person to person are through direct contact with an infected person, such as sexual contact, and sharing of needles for intravenous drug use. Hepatitis A can also be transmitted through coming in contact with contaminated food or water. Also foods that are uncooked or undercooked and have been contaminated with Hepatitis A can transmit the virus. (Bennett,
•The forty five year old patient is diagnosed with the progressive cirrhosis inflaming the liver along with the parenchymal cells. The plain symptoms is manifested primarily because of the augmentation of edema internally in the lower abdomen.
The development of the heart is a complicated process that implicates cell specification and differentiation, including tissue formation, shaping and alteration, to create a functional organ. The zebrafish has become a potential model system to disentangle the fundamental genetic, molecular, and cellular mechanisms of cardiac development and function. The liver is one of the essential organ in mammals. It performs many functions such as help the body digest food, store energy, and remove poisons. The liver also completes many regulatory functions that are critical to fetal development and to life in general. However, failure to perform theses function can result in many mammal liver diseases. Hepatomegaly is a symptom that associate with several liver disorders. Surveys had shown that a large number of the death in the US is caused by chronic liver disease. Liver cancer is another type of liver diseases that is one of the main cause of cancer-related death worldwide.
You look in the mirror and see that your skin and eyes seem a yellowish color, your legs and ankles are swollen, you have abdominal pain and swelling, your skin is also itchy, you have dark urine, and notice that your stool is a pale color. What do these symptoms mean? These are symptoms of damage to the liver. There are many ways to damage your liver like the use of alcohol, but a way you may not be aware of is the use of medication. Some medications when used repeatedly can cause liver damage, such as acetaminophen, also known as Tylenol.
Since there is no definitive cure or treatment for CPM, the best measures to take are preventative. To prevent development of severe neurological lesions associated with CPM sudden changes in the serum sodium levels should be avoided and instead slow correction of hyponatremia should be favored. Immunosuppressive agents’ concentrations should be controlled carefully in order to prevent neurotoxicity in all individuals. When a patient undergoes a LT bleeding during the surgery should be kept to the minimum to reduce the risk of electrolyte fluctuations. When a LT must be done the best effort to avoid CPM is performing the transplant at the earliest stage possible of the hepatic disease (Campos et. al 2011).
There are four phases of Hepatitis B: infection, inflammation, fibrosis, and cirrhosis. In the first phase, HBV invades the liver and goes for the nucleus, where it releases contents of DNA and polymerase into the surroundings. It then maneuvers its way to the cell’s components and enzymes. The polymerase sways the liver cells to make segments of the HBV DNA from RNA. The virus makes liver cells create spare parts for other HBV viruses. Replicas are released from liver cell into the bloodstream, destroying host cell and infecting other healthy liver cells. This entire process can take a few hours to occur, but must continue multiple times for serious damage to occur. The second phase is inflammation. Inflammation is caused by lymphocytes trying to get rid of the virus, but they also release harmful chemicals that damage the cells and take part in damaging the liver. The third phase is fibrosis. Fibrosis is scar tissue caused by inflammation and chronic infection. According to Everson and Weinburg, (2002, pg. 64) “Only 5/10% of people develop chronic Hepatitis B from acute Hepa...
Cirrhosis is a deterioration of the liver resulting from heavy scarring, causing the liver to not be able to function properly. If cirrhosis becomes severe, a liver transplant may be the only solution (“Beyond Hangovers: Understanding Alcohol's Impact on Your Health” 14). It is difficult to calculate when a person will develop cirrhosis, because an alcoholic could never develop the disease, but someone who drinks socially could. It is also unknown why cirrhosis is more prevalent in women (Freeman).... ...
It harmonizes the blood, arranges nutrients, synthesizes proteins, and moves harmful substances out of the body. Prescription drugs, improper diet, and environmental factors can accumulate in the body causing the liver to malfunction. If the liver is not functioning properly serious illnesses and diseases can occur.
The primary cause of hepatic cirrhosis in the United States is long-term alcoholism. Men respond differently than women to alcohol. With women one or two drinks a day can cause them liver damage. Men can consume two to five drinks a day and be ok. One drink a day can create liver scarring. So like everything else in life it varies, it might affect everyone differently. The individual who drinks alcohol on a daily basis, or more often then others have a higher risk of developing cirrhosis. Hepatic cirrhosis has also been linked to serious liver infections such as hepatitis B and hepatitis C. Patients who are HIV positive have died from developing cirrhosis through the hepatitis virus. Other causes of cirrhosis come from reactions to prescribed medications, injuries to the liver, exposure to toxic substances, and episodes of heart failure with liver congestion. Obt...
Increased abuse of alcohol leads to physical damage to the body. Alcohol is absorbed directly into the brain, dulling one’s senses and weakling one's will power. According to the article from the Mayo Clinic Health Information, “Excessive use of alcohol can produce several harmful effects on your brain and nervous system. It also can severely damage your liver, pancreas and cardiovascular system. Alcohol use in pregnant women can damage the fetus” (Mayo 1). Continued ingestion of alcohol affects every organ in the body. Every organ in the body is affected. The liver has serious effects that may lead to cirrhosis and death.. At first the liver adapts and tolerates alcohol. It works harder and finally damages itself in time. Alcohol leads the liver to the inability to metabolize facts. Furthermore, it leads to increase in cholesterol and triglycerides leading to clogged arteries. Red blood cells are also affected leading the individual to become anemic.
These processes can get interfered due to liver failure, when the liver is damaged to an extent that it won’t function normally for months or years. The main causes for liver failure include hepatitis B, hepatitis C, long-term alcohol consumption, cirrhosis and malnutrition (WebMD, n.d.).
Liver cancer is abnormal cell growth on or within the liver. Liver cancer is either starts in the liver (called primary liver cancer) or it spreads to the liver (called metastatic liver cancer). Metastatic liver cancer is more common in United States and Western Europe, while primary liver cancer is common in third world nations. Liver cancer is the third most commonly diagnosed cancer in the world. In the United States, it affects twice as many men as women; the average diagnosis age for liver cancer is 67.
Zein, N. N., & Edwards, K. (2009). The Cleveland Clinic guide to liver disorders. New York: Kaplan Pub.
Alcohol in the form of alcoholic beverages has been consumed by humans since pre-historic times, for a variety of hygiene dietary, medicinal, religions and recreational reasons. According to the NIH Senior Health, drinking too much alcohol affects many parts of the body. It can be especially harmful to the liver, the organ that metabolizes (breaks down) alcohol and other harmful substances. People who drink heavily for a long time can develop diseases such as liver inflammation (alcoholic hepatitis) or severe liver scarring (cirrhosis). Alcohol-related liver disease can cause death. According to the statistics in the year 2010 by the CDC (Centers for Disease Control and prevention) the number of discharges with chronic liver disease and cirrhosis as the first-listed diagnosis was 101,000 persons, while the number of deaths has been 31,903 persons.