Wait a second!
More handpicked essays just for you.
More handpicked essays just for you.
Asthma mechanism of action
Pathophysiology of asthma Essay
Asthma mechanism of action
Don’t take our word for it - see why 10 million students trust us with their essay needs.
Recommended: Asthma mechanism of action
Causes and Effects of Asthma in Children
Asthma is a chronic pulmonary condition effecting the airways and lungs of millions of Americans each year. In individuals with Asthma their airways become swollen, restricted and produce extra secretions ("Asthma," Mayo Clinic). Asthma has causes that range from cold air reaction, pollution within the air, viruses and allergies. The effects of asthma can be particularly hard on children because of underdeveloped lungs. Effects of asthma include restricted breathing, increased chances of viruses, and effects of medications additionally higher chance of hospitalization in children.
One theory is people with the condition have a higher amount of inflammation within their airways. Asthma is an inflammatory disease that is in response to inflammatory cells within the body. These inflammatory cells are known as Mast Cells. Common cells within the body that cause asthma inflammation are T Lymphocytes, Neutrophils, Macrophages and Eosinophil ("About Asthma" Inflammation and Asthma). The effect of different inflammation cells trigger changes from the immune system resulting in extra mucus in the lungs and constriction in breathing.
Another common belief is genetics plays a role in asthma development. In many cases asthma strongly runs within families. For example if the parents have asthma in some cases the child will develop asthma. There are several studies underway looking into the genetic factors in this condition. Currently with the use of genome sequencing there has been a total of five genetic links to asthma development. These genetic discoveries were found through what is known as Positional Cloning. The current genes that are found are ADAM 33, PHF11, DPP10, GPRA and SPINK5 ("Geneti...
... middle of paper ...
... and costs more ("Albuterol vs. Levalbuterol for Asthma Treatment in Children"). When a child is in severe asthma flare it is important to initiate oral steroids over inhaled because it has a better long-term effect on inflammation.
Asthma is a life long condition that affects millions of children each year. The effects of this condition are different for everyone and causes can change throughout the year. The causes and effects on a person very between age groups. Asthma causes range from cold air reaction, pollution within the air, viruses and allergies. Effects of asthma include restricted breathing, increased chances of viruses, and additionally higher chance of hospitalization in children. Asthma results in narrowed airways and difficulty breathing. In certain instances an attack develops resulting from triggers. The use of medication and monitoring is vital.
Ameredes, B. T., & Calhoun, W. J. (2009). Levalbuterol versus albuterol. Current Allergy and Asthma Reports , 401-409.
asthma and lung cancer, the study of its effects on lung development are quite limited; consequently, there
Asthma is treated with two types of medicines: long-term control and quick-relief medicines. Long-term control medicines help reduce airway inflammation and prevent asthma symptoms. Quick-relief, or "rescue," medicines relieve asthma symptoms that may flare up.
Basile, Maria. "Asthma." The Gale Encyclopedia of Genetic Disorders. 2nd ed. 2005. Gale Opposing Viewpoints in Context. Web. 9 Feb. 2011.
Asthma is a disease of the lung that is usually either inherited or it may develop as a severe allergic reaction to a variety of causes. Not everyone who has allergies develops asthma though and not everyone who has asthma has allergies. It is a chronic inflammatory disease 3,5 and it can be very frustrating and difficult to live with if not treated properly. Exercise induced asthma (EIA) is also known as exercise induced bronchoconstriction (EIB). The term exercise induced asthma has been around for quite some time and has been described with symptoms such as wheezing, coughing, shortness of breath, tight feeling in the chest and fatigue. 1,2,3,4 It is usually defined by the following or some close variant: “a condition in which vigorous physical activity triggers acute airway narrowing in people with heightened airway reactivity.”3,4
... certain adrenal cortical steroids are powerful inhibitors of inflammation, toxic side effects limit their usefulness. Similarly, drugs that inhibit proliferation of cells in the inflammatory masses have potentially severe side effects. Drugs that inhibit undesirable inflammation may also inhibit desired inflammatory responses.
Imagine a young child competing with his or her fellow classmates during recess and immediately losing the ability to breathe normally. He or she stops in the middle of the competition and falls to the ground while holding his or her chest trying to find air. When you are young, being able to keep up with your peers during recess and sporting events is very important, however, having asthma restricts this. Asthma has a significant impact on childhood development and the diagnosis of asthma for children 18 years and younger has dramatically increased over the years. Asthma is known as a “chronic inflammation of the small and large airways” with “evident bronchial hyper-responsiveness, airflow obstruction, and in some patients, sub-basement fibrosis and over-secretion of mucus” (Toole, 2013). The constant recreation of the lung walls can even occur in young children and “lead to permanent lung damages and reduced lung function” (Toole, 2013). While one of the factors is genetics, many of the following can be prevented or managed. Obesity, exposure to secondhand smoke, and hospitalization with pneumonia in the early years of life have all been suggested to increase children’s risk of developing asthma.
In addition to various genes affecting the phenotype of asthma, multiple environmental factors like indoor and outdoor air pollution, tobacco smoke, and allergies to pets, molds, common pests (e.g. cockroaches) change gene expr...
Asthma is the leading cause of hospital admissions during childhood. Kumar and Robbins give an accurate definition of asthma as “a chronic inflammatory disorder of the airways that causes recurrent episodes of wheezing, breathlessness, chest tightness, and cough, particularly at night and/or early in the morning” (489). Asthma is a terrifying disease, especially in children, because of the sudden attacks that could claim lives if not treated immediately and effectively. Despite recent advancements in available drugs and overall therapy, the incidence of childhood asthma is rising (Dolovich 373). In order to effectively treat and eventually prevent the onset of asthma, more effective and economical therapies are necessary; although current knowledge has already led to breakthroughs in new drug treatments, the rising incidence rate calls for more. Therefore, to advance the effectiveness of asthma therapies, researchers must first look at the changes caused by the disease, the risk factors that cause or exacerbate it, and lastly understand the mechanisms of the current drugs.
Asthma is also a serious public health issue because it imposes huge impact not only population but also health care systems. According to recent statistics, each year, 5000 deaths, half million hospitalizations, and two million emergency visits are solely explained by asthma [1]. It is also leading cause of absence from school and work. Economic impact is enormous, too. 11 billion dollars of cost was due to only medications of asthma in 1994 [2], which was later increased up to 14 billion dollars in 2002 [3], and still increasing. Unfortunately, this financial burden of asthma falls disproportionately to some vulnerable subgroups: minorities, and children.
It is quite a frightening experience because people with asthma have very sensitive airways. If something irritates the airways of a person with asthma, the airways become red and swollen, and this may be even more difficult for air to pass through the airways into the alveoli and out again. People become breathless and breathe more frequently, which makes them feel more anxious. Secondly, severe asthma can be life-threatening. Suffering from asthma can be frightening to experience and people often feel scared and anxious.
While some people are predisposed to breathing problems because they have asthma in the family, others may find that their asthma is triggered by other factors like things in their environment. To avoid developing asthma, you can look at your lifestyle to ensure you are making healthy choices.
When people hear the word asthma, the first thing that comes to mind is a nerd wheezing and taking an inhaler almost every five minutes, but that is not the case for everyone who is diagnosed with this disease. A person with asthma will often wheeze, become breathless, experience tightness in the chest, and cough at night or early in the morning. Asthma is a chronic respiratory condition and a disease marked by spasms in the bronchi of the lungs, caused by chronic inflammation within the breathing passages. This may...
Asthma is best described by its technical name: Reversible Obstructive Airway Disease (ROAD). In other words, asthma is a condition in which the airways of the lungs become either narrowed or blocked. The results are usually temporary but they cause shortness of breath, breathing trouble, wheezing, coughing, and tightness in the chest. To know what it really feels like to have asthma, I would like everyone to pick up the straw that’s on their desk and put it in their mouth as if they were using it to drink something. Then, pinch your nose. Try breathing for twenty seconds. A real attack can last up to more than 10 minutes and you are only doing it for 20 seconds. If we had more time, I would have the class go to a stairwell and have you run up and down and see what it is like to have asthma while doing other activities.
Even though there is no cure for asthma, there are two main types of medication used for the treatment of it. The first is long term medication that aids in decreasing the inflammation of a person’s airways and also serves as a preventative measure for symptoms and asthma attacks. These medicines are usually anti-inflammatory drugs that are taken daily to reduce future symptoms, but do not act as a quick fix...