Wait a second!
More handpicked essays just for you.
More handpicked essays just for you.
Chronic asthma pathophysiology
About asthma
Chronic asthma case study
Don’t take our word for it - see why 10 million students trust us with their essay needs.
Recommended: Chronic asthma pathophysiology
Introduction
Respiratory disorder mostly affect the upper or the lower respiratory tract, however bacterial or viral infection are the causative agent and the disease is common in all ages. In addition, the lungs and the bronchi can also be affected causing inflammation and obstruction of the airflow resulting to wheezing, chest tightness, stridor, low grade fever, cough, and hemoptysis due severe damage to the lung tissues. Some common disease condition of the respiratory system are pneumonia, croup, asthma, bronchitis, or laryngitis, and tuberculosis, affected disease location determines the signs and symptoms. Hereditary and environmental factors such as allergens and other irritants can be a contributory factors, especially in children. The vulnerability among this group is associated with the respiratory compromise as a result of incomplete airway development (Huether & McCance, 2012).
The purpose of this paper is to describe the pathophysiology mechanisms of chronic asthma and acute asthma exacerbation, and explanation of arterial blood gas pattern during an asthma exacerbation. Also, explain how age might impact pathophysiology of asthma and asthma exacerbation. The diagnosis and treatment plan needed to relieve the presented signs and symptoms will be reviewed. Lastly, the construction of two mind maps for chronic asthma and asthma exacerbation including its epidemiology, pathophysiology, clinical presentation, diagnosis and treatment.
Pathophysiology of Chronic Asthma
Chronic asthma occur when the bronchial mucus membrane are continuously irritated by allergen or irritants initiating inflammatory reaction causing mucosal edema and bronchial spasm causing coughing, wheezing, and sometimes shortness of breath. ...
... middle of paper ...
...nt of asthma depend on the severity, asthma exacerbation needs immediate care with oxygen administration, exercise of the lungs using incentive spirometry, beta-agonist bronchodilator inhaler to relax the smooth muscles. The arterial gas result will determine the presence of alkalosis or acidosis, and mechanical ventilation is needed in the presence of acidosis (Huether & McCance, 2012).
Conclusion
Chronic asthma and asthma exacerbation can affect all ages, however people with chronic asthma should have their inhaler at all times and asthma exacerbation needs immediate medical attention to stop the bronchial spasm and maintain the normal PH by reversing the acidosis caused by retention of CO2. The triggering factors should be eliminated, since ages (especially children and elderly) are predominantly affected, bronchodilator inhaler and immediate help is recommended.
Asthma is a chronic inflammatory disease of the airways. It is a reversible airway obstruction, occurring 8 to 10% of the population worldwide. According to a study in 2005, asthma affects over 15 million Americans, with more than 2 million annual emergency room visits. Asthma patients have a hyper-responsiveness in their airways and generally and increase in their airway smooth muscle cell mass. This hyperplasia is due to the normal response to the injury and repair to the airway caused by exacerbations. The main choice of therapy for asthma patients is β2- adrenergic agonists. Racemic albuterol has been the drug of choice for a short acting bronchodilator for a long time, but since the development of levalbuterol, there is the question of which drug is a better choice for therapy. Efficacy and cost of treatment must both be taken into consideration in each study of these therapies to determine which is best for the treatment of asthma.
Croup: Croup is another common airway inflammation caused by virus that can affect the trachea, larynx and possibility the bronchi (Murray, Sidani, & Zoorob, 2011) thus causing infection in the upper respiratory tract. Murray et al. describes it as the most common illness in children under the age of 6 to 36 months and cause for cough mostly when a child cries; acute stridor and hoarseness in febrile children (Murray et al., 2011). It can be a life-threatening situation in the life of the young infant and the family. Croup symptoms exhibit as hoarseness, barking cough, inspiratory stridor, and respiratory distress. I chose this diagnosis as my first preference because when I read the mother’s subjective report it matches that of croup symptoms: a barking cough, no fever, severe at night and when the baby cries, fatigue due to excessiveness of the tears, pain due to inflames and swollen of the airway. Murray et al., led us to understand that the etiologies of this viral causing agent can be traced to the parainfluenza viruses, type 1. (2011). This virus is commonly spread through contact or droplet secretion.
An asthma attack has many effects on the body. Asthma affects the body by limiting the flow of air into the lungs. It causes airway inflammation, bronchial restriction and irregular airway obstruction. Airway inflammation is how the body reacts to something that is irritating the airways. When happening your lungs begin swelling, your breathing passageway becomes restricted and mucus is secreted. Bronchial restriction happens when the muscles in your airways tighten around the breathing tubes in your lungs. (Bronchial tubes). Mucus or fluid that is accumulated by the reaction can obstruct your airway and make it very difficult to breathe properly.
Asthma is a disorder that interferes with the lungs and the airways to the lungs. It causes attacks of wheezing and difficult breathing. An asthma attack occurs when the airways respond to some kind of trigger, Some examples of triggers for Asthma attacks are dust, mold, pets, exercise, cold weather, and some attacks start for no known reason. The triggers may irritate the airways to the lungs, allowing disease-fighting cells to build up and causing the lungs to swell up. In addition, the airways could get blocked when the muscles surrounding the lungs tighten. This keeps air from circulating freely in the lungs. Or, mucus may clog and narrow the airways in the lungs, making breathing even more difficult.
Asthma is a disease of the lung that is usually either inherited or it may develop as a severe allergic reaction to a variety of causes. Not everyone who has allergies develops asthma though and not everyone who has asthma has allergies. It is a chronic inflammatory disease 3,5 and it can be very frustrating and difficult to live with if not treated properly. Exercise induced asthma (EIA) is also known as exercise induced bronchoconstriction (EIB). The term exercise induced asthma has been around for quite some time and has been described with symptoms such as wheezing, coughing, shortness of breath, tight feeling in the chest and fatigue. 1,2,3,4 It is usually defined by the following or some close variant: “a condition in which vigorous physical activity triggers acute airway narrowing in people with heightened airway reactivity.”3,4
Chronic bronchitis is a disorder that causes inflammation to the airway, mainly the bronchial tubules. It produces a chronic cough that lasts three consecutive months for more than two successive years (Vijayan,2013). Chronic Bronchitis is a member of the COPD family and is prominently seen in cigarette smokers. Other factors such as air pollutants, Asbestos, and working in coal mines contributes to inflammation. Once the irritant comes in contact with the mucosa of the bronchi it alters the composition causing hyperplasia of the glands and producing excessive sputum (Viayan,2013). Goblet cells also enlarge to contribute to the excessive secretion of sputum. This effects the cilia that carry out the mechanism of trapping foreign bodies to allow it to be expelled in the sputum, which are now damaged by the irritant making it impossible for the person to clear their airway. Since the mechanism of airway clearance is ineffective, the secretion builds up a thickened wall of the bronchioles causing constriction and increasing the work of breathing. The excessive build up of mucous could set up pneumonia. The alveoli are also damaged enabling the macrophages to eliminate bacteria putting the patient at risk for acquiring an infection.
Imagine a young child competing with his or her fellow classmates during recess and immediately losing the ability to breathe normally. He or she stops in the middle of the competition and falls to the ground while holding his or her chest trying to find air. When you are young, being able to keep up with your peers during recess and sporting events is very important, however, having asthma restricts this. Asthma has a significant impact on childhood development and the diagnosis of asthma for children 18 years and younger has dramatically increased over the years. Asthma is known as a “chronic inflammation of the small and large airways” with “evident bronchial hyper-responsiveness, airflow obstruction, and in some patients, sub-basement fibrosis and over-secretion of mucus” (Toole, 2013). The constant recreation of the lung walls can even occur in young children and “lead to permanent lung damages and reduced lung function” (Toole, 2013). While one of the factors is genetics, many of the following can be prevented or managed. Obesity, exposure to secondhand smoke, and hospitalization with pneumonia in the early years of life have all been suggested to increase children’s risk of developing asthma.
Liam is a previously healthy boy who has experienced rhinorrhoea, intermittent cough, and poor feeding for the past four days. His positive result of nasopharyngeal aspirate for Respiratory Syncytial Virus (RSV) indicates that Liam has acute bronchiolitis which is a viral infection (Glasper & Richardson, 2010). “Bronchiolitis is the commonest reason for admission to hospital in the first 6 months of life. It describes a clinical syndrome of cough tachypnoea, feeding difficulties and inspiratory crackles on chest auscultation” (Fitzgerald, 2011, p.160). Bronchiolitis can cause respiratory distress and desaturation (91% in the room air) to Liam due to airway blockage; therefore the infant appears to have nasal flaring, intercostal and subcostal retractions, and tachypnoea (54 breathes/min) during breathing (Glasper & Richardson, 2010). Tachycardia (152 beats/min) could occur due to hypoxemia and compensatory mechanism for low blood pressure (74/46mmHg) (Fitzgerald, 2011; Glasper & Richardson, 2010). Moreover, Liam has fever and conjunctiva injection which could be a result of infection, as evidenced by high temperature (38.6°C) and bilateral tympanic membra...
Asthma is chronic inflammatory disorder of the airways characterized by recurring episodes of wheeling and breathlessness. It often exists with allergies and can be worsened through exposure to allergens. In fact, asthma is complicated syndromes that have neither single definition nor complete explanation to the point. In light of its treatment, it is worthwhile to notice that asthma cannot be cured, instead can be only managed by avoiding exposure to allergens and/or by using medications regularly.
Asthma is a result of chronic inflammation of those airways and tubes that supply air to the lungs. It may be cause due to
Secondly, severe asthma can be life-threatening. Suffering from asthma can be frightening to experience and people often feel scared and anxious. The fear and scare can also lead to breathlessness and so mak...
Parker, Steve. "Chronic Pulmonary Diseases." The Human Body Book. New ed. New York: DK Pub., 2007.
Asthma is a serious ongoing disease that affects the airways of both adults and children.5 It is a type of inflammatory disease in your lungs with multiple triggers which may include the flu, indoor allergies, pets, dust mites, exercise, and tobacco smoke. Asthma has been recognized since ancient Egyptian times. Researchers found prescriptions written in hieroglyphics. Aretaus of Cappadonia an ancient Greek master clinician wrote the initial clinical description of asthma. Aaezein is the Greek word from which the current medical term Asthma come. The original Greek term mean ' sharp breath'. There are many people who have this chronic disease. Approximately 7.1 million children are diagnosed, and 18.9 million adults; 8.2 percent of the population of the United States.
Most of you may not think of asthma as a killer disease, yet more that 5,000 Americans die of asthma each year. According to the Mayo Clinic web page, asthma also accounts for more that 400,000 hospital discharges annually. As the number of people with asthma increases, the more likely you are to come in contact with a person who has the disease. As far as I can remember, I have had asthma my whole life. My mother and one of my sisters also have asthma, so I have a first hand experience with it. This morning, I will discuss some interesting facts about asthma, I will specifically focus on what it is, warning signs, symptoms, causes, and the treatments that are used.
Asthma is a disease that currently has no cure and can only be controlled and managed through different treatment methods. If asthma is treated well it can prevent the flare up of symptoms such as coughing, diminish the dependence on quick relief medication, and help to minimize asthma attacks. One of the key factors to successful treatment of asthma is the creation of an asthma action plan with the help of a doctor that outlines medications and other tasks to help control the patient’s asthma ("How Is Asthma Treated and Controlled?"). The amount of treatment changes based on the severity of the asthma when it is first diagnosed and may be the dosage may be increased or decreased depending on how under control the patient’s asthma is. One of the main ways that asthma can be controlled is by becoming aware of the things that trigger attacks. For instance staying away from allergens such as pollen, animal fur, and air pollution can help minimize and manage the symptoms associated with asthma. Also if it is not possible to avoid the allergens that cause a patient’s asthma to flare up, they may need to see an allergist. These health professionals can help diagnosis what may need to be done in other forms of treatment such as allergy shots that can help decrease the severity of the asthma ("How Is Asthma Treated and Controlled?").