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Etiology of bipolar disease
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Abstract Bipolar disorder (also known as manic depression) is a complex disorder in which the core feature is disturbance in mood. Major mood disorder affects 20 percent of the population and is the leading cause of disability worldwide. There are four types of bipolar disorders: bipolar I, bipolar II, bipolar disorder not otherwise specified (BDNOS), and cyclothymic disorder. Bipolar I is the most serious of bipolar disorders due to full manic episodes. Scientist are studying the possible causes of bipolar disorder, and most agree there is no single cause. Some possible cause maybe biological causes, such as genetics and brain structure. Using molecular biology to examine possible genetic factor linked bipolar disorder to genes on chromosomes
1, 4, 6, 10, 11, 12, 13, 15, 18, 21, and 22 (Comer, 2013). Experts believe bipolar disorder may also be caused by problems with brain circuits and the balance of brain chemicals called neurotransmitters (Black Dog Institute, 2013). Bipolar disorder requires long-term management. There is growing evidence that environment and lifestyle issues have an effect on bipolar disorder’s severity. Medication and management of one’s lifestyle is needed to manage bipolar disorder; without medication the likeliness of relapse is increased. In many cases patients may not improve with drug therapy alone, but when used in tandem with psychotherapy social these patients social functioning increase. Some people may suffer years before being properly treated. Symptoms can lead to damaged relationships and poor job or school performance. For effect long-term management of bipolar disorder, people must become educated on the disorder. Steps must be taken to ensure proper diagnosis and treatment, this will enable people to lead full and productive lives.
Bipolar Disorder (Formerly known as Manic Depression) is a mental illness linked to alterations in moods such as mood swings, mania, and depression. There is more than one type, Bipolar I and Bipolar II, and the subcategories are divided by the severity of the symptoms seen, such as cyclothymic disorder, seasonal mood changes, rapid cycling disorder and psychosis. Age of onset usually occurs between 15-30 years old with an average onset of 25 years old but it can affect all ages. (Harvard Medical School; Massachusetts General Hospital , 2013) Bipolar disorder affects more than two million people in the United States every year. (Gardner, 2011)
Bipolar Disorder: The Roller Coaster Ride From Hell Bipolar disorder is a mental illness that is often misdiagnosed, left untreated and misunderstood by the patient, family and friends. Treatment varies among the different types of the disorder. The forms of Bipolar are characterized by symptoms of the patient and the symptoms are treated according to the patient’s needs. However, many symptoms are often misdiagnosed and untreated. Mistreatment or lack of treatment can lead to devastating results.
Bipolar disorder is a lifelong mood disorder characterized by periods of mania, depression, or a mixed manic-depressive state. The condition can seriously affect a person’s reasoning, understanding, awareness, and behavior. Acco...
Lithium and Bipolar Disorder INTRODUCTION The drug lithium has been used for a variety of disorders such as gout, diabetes, and epilepsy for over 100 years. It was not until 1949 when John Cade discovered that lithium had a calming effect on guinea pigs that the possibilities of it being used for mania were explored (Paykel, 1992). Since then, lithium has been established as one of the primary treatments for manic depression disorder. In the body of this paper we will explore the chemistry of lithium, the synaptic transmitters involved, the parts of the neuron affected, the inhibitory and excitatory potential changes, the ion channels effected, the physiological changes, the primary behavior changes, the side effect behavior changes and the effects reported by users. CHEMISTRY Lithium is a chemical element found in group IA of the periodic table, along with sodium, rubidium, and cesium.
Bipolar disorder is a brain disorder that causes unusual shifts in a person's mood, energy, and ability to function.
Bipolar disorder is phychatric disorder in which there are periods of sadness and happiness. Some factors that can lead to bipolar are genetics, neurotransmitters, and brain function and structure. Things that can trigger your bipolar are medicines, the change of seasons, lack of sleep, abuse of substances, and stress.
Is bipolar disorder the cause of great madness or great genius? The symptoms of this mental illness may also be considered as the driving forces behind some of the most gifted and talented people to grace our society. Although individuals with this illness may have some obstacles to overcome, it can be accomplished. With all of the treatment programs that are widely available, people have many options and methods to turn to for help.
Bipolar Disorder can be classified by the occurrence of manic episodes followed by hypomanic or major depressive episodes. A manic episode is a distinct period of abnormally and persistently elevated, extensive, or irritable mood and abnormally and persistently increased goal-directed activity or energy, lasting at least 1 week and present most of the day, nearly every day. During the specific period of mood disturbance and increased energy or activity, many symptoms are present. Some examples of these symptoms can include: -Inflated self-esteem or grandiosity, decreased need for sleep, and are more talkative than usual (“Bipolar and Related Disorders, “n.d.). There is a 10- 15% risk of completed suicide associated with Bipolar Disorder (“Bipolar Depression”, 2)
Bipolar disorder involves going from a state of extreme happiness or concentration to a major depressive state and back to “normal.” Depending on the individual in question, the three states may come in various orders and lengths. For example, the upward swing or the elated feeling of bipolar disorder can last from a week to a few years. The same can be said about the major depressive part of bipolar disorder. The exact length of each state of mind varies amongst each individual. For those who have manic episodes, this can involve intense feelings of being on top of the world or they may indulge in spending recklessly with a lack of consideration of friends and family. Therefore, the bipolar person’s friends and family may feel the need to pay off his or her debts. Unlike manic episodes, people with hypomanic episodes experience extreme concentration and have personal insight. Hypomanic people have the capability to listen to their friends and family. For example, people in a hypomanic state may have the energy to write a book in a single night. Over the last five years, bipolar disorder has been on the rise in the media. More and more stories about bipolar are being published in the newspaper, films, television, and online videos, and passed on through word of mouth. More often than not, these stories involve people who are exhibiting bipolar traits. Although bipolar disorder does have some negative parts to it, the stories portrayed in the media often involved only the most severe bipolar cases. Therefore, messages in the media often involve myths. Certain sources do not involve myths but have the potential to cause misinformation. Media messages can become biased. There are many bipolar disorder myths that come from word of mou...
The severe mood fluctuations of bipolar or manic-depressive disorders have been around since the 16-century and affect little more than 2% of the population in both sexes, all races, and all parts of the world (Harmon 3). Researchers think that the cause is genetic, but it is still unknown. The one fact of which we are painfully aware of is that bipolar disorder severely undermines its victims ability to obtain and maintain social and occupational success. Because the symptoms of bipolar disorder are so debilitation, it is crucial that we search for possible treatments and cures.
Childhood Onset Bipolar Disorder (COBPD) is one of the most debilitating mental disorders affecting children today. Bipolar Disorder is a mood disorder usually affecting adults that causes sometimes severe changes in mood. Childhood Onset Bipolar disorder is just what it sounds like, a bipolar disorder that occurs during childhood. Persons suffering from a bipolar disorder experience mood swings ranging from depression to mania. During a depressive episode patients can experience feelings of extreme hopelessness or sadness, inability to concentrate and trouble sleeping. Symptoms of mania include rapidly changing ideas, exaggerated cheerfulness and excessive physical activity. Hypomanic symptoms are the same as in mania, however, they are not so severe as to require hospitalization. The fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) outlines the diagnostic criteria for mood disorders. According to the DSM-IV, a person must have at least 5 of the following symptoms during the same 2 week period to qualify as a major depressive episode: a depressed mood lasting most of the day for several days; a significant weight gain or weight loss; a loss of interest in activities; difficulty sleeping (insomnia) or an increased need for sleep (hypersomnia); restlessness or slowed pace observable by others; daily fatigue; feelings of guilt or worthlessness; inability to concentrate; or recurrent thoughts of death. These symptoms can only be diagnosed as a depressed episode if they are not better explained by grief, effects of a drug, or a medical condition. The person experiencing these symptoms must, also report an interference in their daily functioning because of the ...
Bipolar disorder is also known as manic-depression disorder, may cause unusual changes in mood and behavior such as grandiosity, decreased energy, distractibility, diminished interest, insomnia, pressured speech, suicidal thoughts, and decrease in the ability to carry out day to day tasks (Diagnostic and Statistical Manual of Mental Disorders; 5th Ed.; DSM-5; American Psychiatric Association, 2013). According to Jann (2014) the symptoms of bipolar disorders are severe alternating between normal ups and downs leading in damaged relationships, poor job and school performance, and even suicide among the most severe. There are four types of bipolar disorder which include bipolar I disorder, bipolar II disorder, bipolar disorder not otherwise specified, and cyclothymic disorder Jann (2014).
Although genetic factors are considered the most important for the development of bipolar disorder, “episodes that develop after the first one appear to be more heavily influenced by environmental stress, sleep disruption, alcohol and substance abuse, inconsistent drug treatments, and other genetic, biological, or environmental factors” (Milkowitz, 2010, p. 74). Patient M had already suffered two similar episodes of strange behavior and her family history includes mood disorders and states of depression.... ... middle of paper ... ...
Bipolar disorder is the condition in which one’s mood switches from periods of extreme highs known as manias to periods of extreme lows known as depression. The name bipolar comes from the root words bi (meaning two) and polar (meaning opposite) (Peacock, 2000). Though often bipolar disorder is developed in a person’s late teens to early adulthood; bipolar disorder’s early symptoms can sometimes be found in young children or may develop later on in life (National Institutes of, 2008). Bipolar disorder has been found to affect both men and women equally. Currently the exact cause of bipolar disorder is not yet known, however it has been found to occur most often in the relatives of people diagnosed with bipolar disorder (National Center for, 2010).
Bipolar disorder is a lifelong condition that can affect how you feel and how you act. It is a mood disorder caused by chemical imbalances in the brain that can result in extreme mood swings, from manic highs to depressive lows. Also known as manic-depressive disorders, bipolar disorder is categorized and determined as “a psychological state in which a person experiences a mood disorder causing radical alterations in their moods”. Elevated levels of either manic or depression are very common with a person affected by a bipolar disorder.