The set of chromosomes that an individual has is called the person’s karyotype. A karyotype test is one of the many important tests performed when determining a person’s gender. This test is done by collecting genetic information about a person including their chromosomes. Examining these chromosomes through karyotyping allows determining whether there are any abnormalities or structural problems and also if the person is male or female. A human has 23 pairs of chromosomes. Twenty-two of these pairs, are called autosomes, and they look the same in both males and females. But the 23rd pair, the sex chromosomes, is different between males and females. Females have two copies of the X chromosome, while males have one X and one Y chromosome.
The first step taken in karyotype test is by taking a sample of your Mitosis cells. These samples can be taken from various tissues, including bone marrow, amniotic fluid, blood, or placenta. The sample is then placed in a laboratory dish that allows the cells to grow and multiply. Then the dividing cells are stopped in metaphase by treating it wit...
revealed that three of the fourteen samples were were homozygous while the other eleven were
The procedure of the test is simple hence patients will then be asked to remove their clothes and wrap and cover with a paper cloth around the waist before the Pap test. Patients will then be asked to lie back on the examine table with their legs spread open .Knees have to be bent and feet sitting on rest position. The clinician or gynecologist will insert the lubricated instrument called speculum into the patient’s vagina in a way that will hold open to see the cervix clearly. The clinician will examine to see if there is any visible problem and will gently scrape the surface of the cervix with the help of wooden scraper or spatula to obtain the sample of the cells. The liquid sample will then be smeared on a glass slides and will be brought to a laboratory to analyze where microscope slides will be ready for the test. The clinicians will have to repeat the test if the result is abnormal .Cells abnormalities are divided as follows ASC atypical squamous cells ,AGC,AIS,LSIL.
Genetic disorders can be caused by many of the 46 chromosomes in human cells. This specific disorder is linked to a mutation in the long arm of the X, or 23rd chromosome. The mutation is recessive, meaning a normal X chromosome can hide it. Females have two X chromosomes allowing them to hide the mutated recessive one, making them a carrier of the gene, while males only have one X chromosome, meaning that they are unable to hide the mutation and they become effected by the disease. Therefore if a male carries the gene, he is affected because he has no way of dominating the recessive gene, but if a female carries it, she is only a carrier and has a 50/50 chance of passing it on to her baby. This may seem like a high probability however, only one in every fifty thousand male births will have this immunodeficiency disease.
Jacob Syndrome is a rare condition where males contain an additional copy of the Y chromosome in their cells. According to the Genetic and Rare Diseases Information Center, (GARD, 2012), other names for Jacob Syndrome include: 47, XYY syndrome, XYY Karyotype, and YY syndrome. Statistics from Genetics Home Reference (2014) state that Jacob Syndrome appears in approximately 1 in 1,000 male newborns. In the United States, 5 to 10 male newborns have Jacob Syndrome.
Every cell contains forty-six chromosomes (twenty-three pairs). One, out of the twenty-three pairs, is in control of a person’s gender. There two different kinds of chromosomes: X and Y. Males are born with one X chromosome and one Y chromosome. Females, however, are born with two X chromosomes. According to Cindy Dunham and Catherine H. Ward, girls with Turner syndrome are missing part of, or all of the X chromosome (3). The chromosome becomes absent before or shortly after conception (Overview par. 3). Girls diagnosed with Turner syndrome are confirme...
This means that all the sperm in males and eggs in females are produced from meiosis. Sperm and egg cells are haploid cells-they contain only one of each type of chromosome. Meiosis actually starts with a diploid cell that undergoes two divisions; the end products are four gametes, all genetically different. Meiosis is known as a reduction division because the daughter cells always contain half the amount of chromosomes as the diploid beginner cell. Chromosomes come in pairs and these pairs are called homologous pairs. Homologous chromosomes mean that both of the chromosomes in the pair have the same gene sequence. Human somatic cells(diploid) contain 46 chromosomes consisting of 23 homologous pairs; therefore, human gametes, which are haploid, have 23 total chromosomes-one from each homologous pair. Just like in mitosis, meiosis undergoes all of the same phases. However, because meiosis involves two divisions, the cell goes through all the phases twice. When referring to the first time the cell undergoes a phase, we say 1, and when referring to the second time, we say 2. For example, when a cell starts prophase the first time in meiosis, we say it is going through prophase 1(P1). Also, there are some differences in the process itself. During P1, homologous chromosomes exchange a section of themselves in what is known as crossing over. This provides a source of genetic variation since part of each chromosome switched places with each other, thus making both chromosomes distinct from the original. Another important difference to know is that in anaphase 1, the doubled chromosomes are not separated into sister chromatids. This doesn’t happen until A2 to ensure that each of the four gametes receives one of each kind of chromosome. There are many key points to understand about meiosis. The first being that cells in meiosis do not go through interphase twice. Interphase is a “one-time” thing; DNA
To begin with, gender must be examined at the basic level of science in regard to physical and biological development of humans. We all understand the physical differences between the male and female gender, but how is our sex actually determined. After conception,
From the moment sperm and egg meet, many processes begin to happen. Each of these processes are the start of forming all of the parts that make up a human being. Most people wonder if their new baby will have the eyes of the mother or the father, be tall like Grandpa or short like Aunt Kim. Be an excellent athlete like Uncle Tom or have the ability to be a rocket scientist like Grandma Sue. New parents also spend a lot of time thinking about if they will be having a boy or a girl. Twenty-two pairs of autosomes is how many it takes to form a whole homo sapien. In addition, one pair of sex chromosomes is needed. These will either be in the form of two X chromosomes to form a female or an X and a Y chromosome to form a male. This pair of sex chromosomes is responsible for much more than just the external sex organs. They control hormones, the full internal reproductive structures, and the sex discernment within the brain.
Gender is determined by the sex chromosomes, XX produces a female, and XY produces a male. Males are produced by the action of the SRY gene on the Y chromosome, which contains the code necessary to cause the indifferent gonads to develop as testes (1). In turn the testes secrete two kinds of hormones, the anti-Mullerian hormone and testosterone, which instruct the body to develop in a masculine fashion (1). The presence of androgens during the development of the embryo results in a male while their absence results by default in a female. Hence the dictum "Nature's impulse is to create a female" (1). The genetic sex (whether the individual is XX or XY) determines the gonadal sex (whether there are ovaries or testis), which through hormonal secretions determines the phenotypic sex. Sexual differentiation is not drive...
In today’s world, people are learning a great deal in the rapidly growing and developing fields of science and technology. Almost each day, an individual can see or hear about new discoveries and advances in these fields of study. One science that is rapidly progressing is genetic testing; a valuable science that promotes prevention efforts for genetically susceptible people and provides new strategies for disease management. Unnaturally, and morally wrong, genetic testing is a controversial science that manipulates human ethics. Although genetic testing has enormous advantages, the uncertainties of genetic testing will depreciate our quality of life, and thereby result in psychological burden, discrimination, and abortion.
Inside the cells that produce sperm and eggs, chromosomes become paired. While they are pressed together, the chromosomes may break, and each may swap a portion of its genetic material for the matching portion from its mate. This form of recombination is called crossing-over. When the chromosomes glue themselves back together and separate, each has picked up new genetic material from the other. The constellation of physical characteristics it determines is now different than before crossing-over.
Typically males have XY chromosomes, and women have XX chromosomes; however, hermaphrodites are neither male nor female. One reason comes from Turner's Disease where the chromosomes are XO, and there is a sex chromosome missing. Another mutation is the XXY chromosomes, known as Klinefelter's Disease, which occurs in an average of one out of every 1000 births. There is also, Mosaicism, where different cells split into different parts, making up XY and XO chromosomes. Hormonal complications can change the gender...
Typically, XX chromosomes designate females and XY designate males, which both of these will develop into socially acceptable genders of the assigned chromosomes. Although this is mostly correct, there are some variations to the rule in which a person will differ from the assigned chromosomes and have physiological differences that will affect gender identity development. Eliza Dragowski, an assistant professor psychology, writes in a report titled Childhood Gender Identity… Disorder? Developmental, Cultural, and Diagnostic Concerns, "The second path points to anatomical brain differences. It is supported by postmortem examinations of brains of male-to-female transsexuals, which show a typical female-sized portion of the central subdivision of the bed nucleus of the stria terminal, a brain area vital in sexual behavior." This proves brain similarities between males and females, which can lead to them becoming transsexuals later in life. Their brain affects how they develop their own gender identity. Furthermore, genetic differences influence a developing identity, "review of the most recent research indicates the presence of various genetic variations that do not cause changes in reproductive anatomical structures but may produce gender-variant identities” (Dragowski). A variation of these genes will have a significant effect on gender since its part of their
Sex and gender are terms that are mixed up from day to day and seen as similarities rather than differences. Sex is what distinguishes people from being either male or female. It is the natural or biological variation between males and females (Browne, 1998). Some of these variations are genital, body hair, and internal and external organs. It is the make-up of chromosomes, men have one X and one Y chromosome and women have two X chromosomes, which are responsible for primary characteristics (Fulcher and Scott, 2003).
The diagnostic procedure for the reproductive system are the following a carrier test to determine if an individual only carry one copy of altered gene or an exact recessive gene. The recessive gene refers to the disease that both copies of the gene of a person with the disease related to mutation. The second is