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References on the importance of evidence based practice in patient care
Evidence based practice in a clinical setting
Evidence based practice in a clinical setting
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For a lot of illnesses such as a cold or an upset stomach, most people would take a general medication like painkillers or a general decongestant for clearing a blocked nose as a “one size fits all”. Personalised medication is defined by the European Commission as “a medical model using molecular profiling for tailoring the right therapeutic strategy for the right person at the right time, and/or to determine the predisposition to disease and/or to deliver timely and targeted prevention.” (Personalised Medicine Coalition, 2014) (Directorate General for Health and Consumers; Directorate General for Research and Innovation, 2013). Personalised medicine was accepted quickly and a dedicated journal, “Journal of Evidence Based Medicine” was launched …show more content…
For one, it costs a lot of money for the research and equipment needed for the diagnostics (Jakka & Rossbach, 2013). Patients may also hear about an amazing and innovative treatment in the media and that they would then hear would not apply to them because of their genetic makeup which could lead to a breakdown in communication between the patient and the doctor (Cuticaaa, et al., 2014). There is also a privacy issue in that the patient’s genomic profile may be stored on a database for research uses and some patients may not want their DNA profile for anyone to see if it’s not for the purpose of their own treatment (Caplan, 2016). Patients may also find out things they would not want to. For example, if comparing the genetic profiles of family members to see if a disease is passed down through family it could be found that a parent is not the blood-relative of their child which would most likely lead to an angry patient. However, this could be an advantage as the profile could reveal that a patient might be at a greater risk of a disease which has not shown any symptoms yet and measures could be taken in order to reduce the risk factors (Caplan, 2016). Any doctors who would like to suggest a personalised therapy to a patient would have to be trained and educated on what their medicine is and how it works so they are able to give as much information as they can to their patient (Najafzadeh, et al., …show more content…
Doctors in training should be educated on personalised therapy as soon as possible so new discoveries and methods can be put into the public as quickly as possible. As was seen with the human genome project it took 13 years (1990 to 2003) to complete and cost 2.3 billion dollars (NHGRI, 2010). Nowadays, companies are offering to sequence anyone’s genome for just under a thousand dollars and takes about 8-10 weeks upon receiving a DNA sample (Front Line Genomics, 2016). With how easy and affordable personalised medicine is becoming I think that in the near future it will be the most common method of curing out most diseases and maybe even find ways of preventing them from even happening due to the patient’s knowledge of their risk
The PBS documentary “Nova – Cracking Your Genetic Code” tells about the genome sequencing technology: its current possibilities, advantages, disadvantages and future potential. The system became cheaper, faster and more available since the first human genome was fully sequenced in 2000. Modern companies use the technology to provide clients with the information about their genes and impacts they can have on owners’ health. Hospitals can provide more accurate diagnosis and personalized treatments with the aid of the genome sequencing. The video shows several examples of these benefits. But it mentions concerns about the quality of services, risks of exaggerated
The public should be aware of what could happen if this kind of information became public knowledge, and of the opportunities that the knowledge brings. There is no doubt that the information from genetic analysis is going to help a lot of people with all sorts of problems live longer and healthier lives. The only problem is that we have to keep the information in the hands of those who need it, and out of the hands of those who would use the information to profit or discriminate.
The system has been fraught by delays in receiving treatment, a backdrop of layered bureaucracy, and lack of advanced technology. Currently, the UK system has a limitation on the use of experimental treatment which deprives people of their rights as citizens. Regulating cost and price points will serve as a disincentive for companies in the healthcare sector from coming up with new technologies to better health
...based medicine: what it is and what it isn't. British Medical Journal. 312:71 [online] Last accessed on 13th February 2014. [Available at:] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2349778/pdf/bmj00524-0009.pdf
It was in the 1980’s that scientist began looking at alternative ways of treatments, one is gene therapy. Scientist would insert human genes into a bacteria cell. Then the bacteria cell would transcribe and translate the information into a protein. Once that is done the scientist would then introduce the protein into human cells. Gene therapy can be simply viewed as inserting bits of foreign DNA into a patient’s tissue in hope...
Preventative medicine comes with the potential for making our lives both better and worse. Today the world in which we live in has faced steady medicalization of daily existence. Many factors have contributed to the rise of medicalization. For instance the loss in religion, the increase of faith in science, rationality, progress, increased prestige and the power of the medical profession. The medical profession and the expansion of medical jurisdiction were prime movers for medicalization. Medicalization has also occurred through social movements. Doctors are not the only ones involved in medicalization now, patients are active collaborators in the medicalization of their problem. Critics try to argue for or against the idea that this leads to a favorable versus a non -favorable outcome. This increased establishment and development of medicine, including technoscience, has resulted in a major threat to health. The medicalization of normal conditions, risks the creation of medical diagnoses that are widely inclusive and that hold the potential for further expansion. Many biologically normal conditions, like shortness, menopause, and infertility, are currently considered medical problems. These naturally occurring states are now regarded as undesirable and deviant. This process is referred to as medicalization. Although they are considered deviant, however, the process of medicalization also removes culpability: a person’s problems can be ascribed to a chemical imbalance rather than seen as reflecting his or her character or accomplishments. Some of the articles I will be looking into are Dumit’s “Drugs for life” as well as Healy’s “Pharmageddon” and Cassel’s “Selling Sickness” to explore if this process of overmedicalization has le...
Over 40 years ago, two men by the names of James Watson and Francis Crick discovered deoxyribonucleic acid, or DNA. DNA is hereditary material in humans and almost all other organisms (What is DNA?). From this finding, gene therapy evolved. Today, researchers are able to isolate certain specific genes, repair them, and use them to help cure diseases such as cystic fibrosis and hemophilia. However, as great as this sounds, there are numerous ethical and scientific issues that will arise because of religion and safety.
... to be practical doctors would need be able to identify all of the genes in each of their patients bodies and analyze them in a timely fashion, in order to give them timely and proper medical advice. Right now this is unrealistic. Therefore they use racial profiling, not in order to discriminate, but in order to give the best and most efficient medical advice possible.
... therapy. With further research and development it might just be possible to take the genetic evolution of the human genome into our own hands. However, it is no surprise that there are some that question the ethical background of such a procedure.
Gene therapy is a technique which has developed in the wake of recombinant DNA (rDNA) technology. It is a process which results in the correction of a genetic disorder by the addition of a piece or fragment of DNA into the genetic material of a living, functioning cell. A mere thirty years ago this concept belonged to the realm of the human imagination made manifest in the works of science fiction. Today it belongs to the realm of the human imagination made manifest in the works of science, period. It is mind boggling to try to comprehend the far reaching effects of gene therapy. How is it affecting society? Who will benefit from its use? Should it be used at all? Should research continue? How do we answer all of these questions? The answers are not readily available, nor are they black and white, but an attempt at finding some solutions must be made. Before exploring this line of thought further, a basic understanding of the technical aspects of gene therapy is essential.
In September 14, 1990, an operation, which is called gene therapy, was performed successfully at the National Institutes of Health in the United States. The operation was only a temporary success because many problems have emerged since then. Gene therapy is a remedy that introduces genes to target cells and replaces defective genes in order to cure the diseases which cannot be cured by traditional medicines. Although gene therapy gives someone who is born with a genetic disease or who suffers cancer a permanent chance of being cured, it is high-risk and sometimes unethical because the failure rate is extremely high and issues like how “good” and “bad” uses of gene therapy can be distinguished still haven’t been answered satisfactorily.
The implementation of a universal health care system in the United States is an important challenge that needs to be overcome. There are numerous amount of editorial that argue on both sides of the debate. Some people argue that a universal health care system would bring costs down and increase access to care while others argue that a universal health care system would be too expensive and reduce the quality of care. The correct answer requires intensive understanding and economics to overcome, the arguments must be examined for a proper answer.
Due to the human genome project and other genetic research, tests for mutation which cause diseases have been developed. The list of these illnesses include several types of cancer. Doctors have estimated that as many as 3,000 diseases are due to mutations in the genome. These diseases include several types of colon cancer in which three different genetic tests have been already developed. Debates have arisen on whether these tests should be used regularly or not. Questions including the patients= rights of privacy and the possibility of loss of health or life insurance have been argued over in both the media and political arena.
First, let's consider the situations in which genetic testing would be beneficial to patients. Genetic testing for diseases that are preventable or treatable could allow individuals to alter their lifestyles so as to treat the disease or reduce their risk of developing the disease. For instance, the E2 version of the APOE gene, which is found on chromosome 19, has been linked to heart disease (Ridley, 1999). Individuals who have two copies of the E2 gene are particularly sensitive to high-fat and high-cholesterol diets. Therefore, a genetic test to determine whether a person has the high-risk version of the APOE gene could inform a person of future health risks, thereby allowing the person to change his diet to help prev...
The procedures that will be the future of modern medicine currently fall into the realms of taboo and fictional. These procedures encompass every aspect of medical science, from exploration of the human body, curing diseases, to improving a person’s quality of life. Many of these procedures are not very well known, while a few have been in the spotlight. These procedures include cloning, nano-robotics, retro-viruses, and genetic manipulation via gene-specific medications. For any serious breakthroughs in modern medical science, we must embrace these new forms of treatment instead of shying away from them. Second, I’ll attempt to explain how these methods and procedures could benefit mankind.