1. Introduction – monogenic diabetes results from mutations in a single gene. 20 genes have been linked to monogenic diabetes. A mutation in any one of these gene can cause a child or adult to develop monogenic diabetes. If an individual has a mutated gene then this mutation may be passed from parents to their children or may spontaneously occur in an individual. there are two main forms of monogenic diabetes – 1. MODY (Maturity onset diabetes of the young) – most commonly caused by mutations in
pre-mRNA. The pre-mRNA consists of splicing and non-coding regions. pre-mRNA molecules are much longer than the mRNA molecule needed to code for its protein. The regions that do not code for amino acids; aa, are scattered all along the coding region. The genes are split with coding regions, called exons, short for expressed regions; in between the exons the non-coding region called introns exist. Before the translation of mRNA the introns must be spliced off. Splicing is an complicated process for
Home Confinement: An Alternative to Incarceration West Virginia state prisons have a maximum capacity of 2,154 inmates; currently they house 2,363 inmates, and more remain in City and County lockups to manage the overflow (West Virginia Blue Book). Home Confinement solves this problem. Reduction of the prison population should be reason enough to institute home confinement, but other reasons do exist. Would you like lower taxes? Home confinement costs much less than incarceration. Do you favor
Drinking and the Dive Bouteille in Antonine Maillet's play Panurge In her play, Les drôlatiques, horrifiques et épouvantables aventures de Panurge, ami de Pantagruel d'après Rabelais, Antonine Maillet recreates beautifully the fantastic and incredible atmosphere present in the original works of Rabelais. She cuts and pastes together the most well known and exceptional selections of Rabelais' original text and creates a new story, adding along the way some finishing touches which give the play
A Feminist Alternative to Fetterley's Criticism of A Farewell to Arms After finishing A Farewell to Arms, I found it difficult to reconcile Judith Fetterley's feminist attack of the novel with my own personal opinions. I agree that Hemingway does kick women to the curb in his portrayal of Catherine, but my reasons for pinning this crime on Hemingway are different from hers'. Although she means well, Fetterley makes the ridiculous claim that by portraying Catherine as an angelic, selflessly loving
Transcendental Meditation: Alternative Therapy for Alcohol Abuse Proponents of the Transcendental Meditation program initiated by Maharishi Mahesh Yogi have expressed their ideas in various web sites on the World Wide Web, through pages such as The Transcendental Meditation Program at http://www.tm.org and the Scientific Research on Transcendental Meditation and TM-Sidhi program of the Maharishi University of Management at http://www.miu.edu/TM_Research. In these sites positive messages are
Douglas Coupland’s Generation X: Tales for an Accelerated Culture: an alternative voice On production of his first novel, Coupland was labelled by critics spokesman for a new lost generation - “Generation X” - those individuals aged between mid-twenties and mid-thirties who have come of age in an increasingly technological and materialistic bureaucratic society. As a consequence, they are emotionally scarred and alienated, reject conformity and search for some kind of meaning to life. When asked
few effective techniques, will help produce better decisions. What is Decision Making? Some Definitions A good place to start is with some standard definitions of decision making. 1. Decision making is the study of identifying and choosing alternatives based on the values and
Adoption, the Moral Alternative to Abortion It was only three days after being born that I was flown to my new family in Illinois. If I had not been for a one woman’s unselfish decision, I would not be writing the words on this page right now. Abortion is an ethically wrong decision and option for a parent. It is illegal to take the life of another human being; by choosing to have an abortion, legally a parent is not willingly killing a human life. However, this choice is still seen as a murder
I was intimidated. Actually, let me be honest, I feared a thrashing at the hands of the River God. Trembling muscles warned me to just shoulder my boat and walk. I couldn't. I traveled all the way from Pennsylvania to run these rivers, how could I back out now? I had to run Sunshine Falls...the largest rapid on the Royal Gorge section of the Arkansas River. When would I make it back to Colorado to run this river? I considered the the portage again; it's an impressive drop with no shame in walking
Alternatives to Capitalism Explored in Thomas More's Utopia Thomas More's use of dialogue in "Utopia" is not only practical but masterly layed out as well. The text itself is divided into two parts. The first , called "Book One", describes the English society of the fifteenth century with such perfection that it shows many complex sides of the interpretted structure with such clarity and form that the reader is given the freedom for interpretation as well. This flexibility
Beauracracy There are many alternatives that are used to motivate workers beyond the conventional bureaucratic ways that was once thought of as the only way to control workers. Since the 1960's we have learned a great deal of information leading to the discovery of alternatives to bureaucratic organizations. Today, bureaucratic ideas are still widely used among organizations, however a shift in thinking occurred and the question was asked, What are the alternatives if bureaucracy it not working
In the past decade there has been a great deal of worrying about what will happen when the world’s oil supply becomes depleted. The main reason for concern is that almost all of the automobiles in use now require an oil based gasoline to run their internal-combustion engines. In the next few decades it is predicted that all of the world’s oil will have already been mined, and combustion engines will be unable to function. For this reason many companies such as Ford, Mercedes-Benz, Chrysler, Toyota
Interpretation Alternatives of The Tempest A production of The Tempest should emphasize the idealized methods in which Prospero uses magic to solve the problem of revenge which is so prevalent throughout his tragedies, perhaps the production might be a direct allegory for the magic of the theatre itself. In this conception of the play, the scattering and bringing together of the characters in the script is significant in that theatre also could be said to bring people together and allow them
Reflection on Alternative Assessments Traditional and alternative assessments share some key elements, yet differ as well. All assessments, whether given as a test after a unit or alternative, should be measurable and be reliable and valid by having clear criteria to measure the learning targets. Traditional and alternative assessments generally differ in timing, feedback, student's involvement, and how the teacher uses the information. The time in which traditional assessments such as after
intrinsic badness. Simply, getting what you desire most is good, not getting that is bad. The source of value is not the pleasure gained by getting what you want; rather the fulfilment of the desire as an end in itself. This view came about as an alternative to traditional hedonism, especially after Nozick's Experience Machine showed that most people would not choose not to be most efficiently pleasured through the machine, and therefore we should look to things other than pleasure as sources of value
To solve this problem, the company management must investigate the environment of the workplace. They must investigate the employees’ needs and take necessary measures to solve the problem. Overview of Alternatives In solving the problem of absenteeism and lateness, the best solution should address the employees’ needs and make them have the zeal to regularly attend to their workplaces. One of the possible solutions is the development of a rewarding scheme
Alternatives for Pregnant Women in the Correction World In the correction world there is a lot to deal with and one big aspect of it is that there are many women that go into jails or prisons pregnant or already having children. The amount of women in jails or prisons keeps rising over the years. There are better ways then keeping pregnant women in jails. Alternatives for these women are in there best interests. The numbers of women in jails or prisons have increased greatly over the years
ALTERNATIVES TO OIL Peak oil is a huge problem that is facing the United States in the near future. Gas prices will skyrocket forcing most people to become self-sufficient. In other words, people are not going to be able to depend on the supermarket to get food. No more dining out, or going to the movies or traveling for vacation. The United States alone consumes nearly 7.5 billion barrels of oil each year. It would practically be a miracle for an alternative to be found and compensate for the forty
search for alternative methods that will help us to obtain success. Competition may also do good for our character and personality. An over-confident person may keep doing things his or her way in hope of getting what they want. However, after experiencing many disappointing failures, this proud and narrow-minded person may be humbled in the process of attempting to reach his or her goal. Still in search for alternatives for competition, I stand my ground in that there are no alternatives for competition