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Electroconvulsive therapy essay
Literature on electroconvulsive therapy
Literature on electroconvulsive therapy
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The purpose of this paper is to inform the reader about Wilder Penfield and his research over electric brain stimulation. This essay will give a brief biography of Wilder Penfield, a description of his research, and finally discuss the insight his experiments provided and the influence they had on our body and behavior in general.
Wilder Penfield was born in Spokane, Washington, on January 26th, 1891. He spent most of his youth with his mother in Hudson, Wisconsin. In 1904 his mother told him about the Rhodes Scholarship, which is awarded annually for students who study at Oxford University, she said confidently that it was the scholarship for him. Against his better judgment he prepaid over the next few years to become an athlete at Princeton University. While there he decided to pursue medicine like his father and grandfather before him.
In the 1950s, Penfield tried to treat patients with epilepsy by using a mild electric stimulation to the brain. He thought the electric currents would trigger the cause of epilepsy allowing him to pinpoint and remove or destroy it. During his experimental surgery Penfield discovered that stimulation anywhere on the cerebral cortex could bring responses. He also discovered that
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stimulation of the temporal lobes could trigger integrated responses such as memories that included sound, movements, and even color. The patients were fully conscious with the aid of local anesthetics, as he opened their skull to conduct his experiments. Thanks to Dr.
Penfield’s recherce and brain stimulation he was able to map the brain and its functional organization in living people. During his experiments he found that sending a shock to certain parts of the brain would have different reactions. By using this method Penfield was able to find the cause of epilepsy seizers and destroy it. In one case the patient would smell burnt toast right before a seizer, he used this knowledge to probe the limbic system to recreate the smell. None of this would have been possible without the map he created, the map was so influential that it is still used today. However, we no longer need to cut open the skull to see what inside, thanks to modern medicine MRIs are used to see what’s going on in our
heads. Dr. Penfield’s recherce has made an impact on the way we go about diagnose patients with mental problems. Some of his achievements include writing books in medical and diverse non-medical subjects, created the Montreal neurological institute, and improved neuroscience techniques with a cure for epilepsy (Canadian Encyclopedia, 2015). His scientific papers and handbooks are still being used today as standard references on brain function (US National Library of Medicine, 1977). Penfield also founded the Montreal Neurological Institute and Hospital, which is the world’s leading destination for brain research and advanced patient care. In conclusion, Dr. Penfield’s life can be summed up by nothing less than extraordinary. With the motto, "Brain surgery is a terrible profession. If I did not feel it will become different in my lifetime, I should hate it." (1921). And titles like “the greatest living Canadian”, there is no doubt that he has made a positive impact on everything he touched. One thing to take away from this article is compassion and dedication. With these two traits, Dr. Penfield developed many ground breaking techniques and discoveries that improved the lives of all his patients.
Lawrence Douglas Wilder was born in Richmond, Virginia on January 17, 1931. He was named after abolitionist Fredrick Douglas and poet Paul Lawrence. He was from a large family, being the second youngest of 8 children, with one brother and six sisters. His father, Robert was a salesman and supervisor of agents for a black-owned insurance company. His mother Beulah (may also be Eunice depending on the source), worked as a maid. His grandparents, James and Agnes Wilder were slaves making him the grandson of slaves. His family lived in a poor and segregated neighborhood. Mr. Wilder said he remembered his childhood as “gentle poverty.” (Source 2)
The learners were a part of Milgram’s study and were taken into a room with electrodes attached to their arms. The teachers were to ask questions to the learners and if they answered incorrectly, they were to receive a 15-450 voltage electrical shock. Although the learners were not actually shocked, the teachers believed they were inflicting real harm on these innocent people.... ... middle of paper ...
Weiner R. D., & Krystal, A.D. (February 1994). The present use of electroconvulsive therapy. Annual Review of Medicine, 45, 273-281.
Halig, Steven et.al. History of Electroconvulsive Therapy. New York: Harcourt, Brace and World, Inc., 1999.
Psychiatrists observed that after spontaneous epileptic seizure the psychiatric conditions of patients improved. Previously, in the sixteenth-century, Paracelsus, a Swiss physician and alchemist gave camphor by mouth to produce convulsions and to cure lunacy. Originally, the induced convulsions treated severe catatonic stupors and schizophrenia. Today we know the convulsions are secondary to grand mal seizures in the brain, and that the seizure is the primary therapeutic agent of electroconvuslive therapy (ECT). Metrazol and Cardiazol later replaced Camphor because of its rapid onset. The extremely unpleasant sensations led investigators to seek alternative methods and electroconvulsive therapy was born. Electrical stimulation first tested epileptic seizures on dogs and pigs, and its first treatment helped a delusional, hallucinating homeless man diagnosed with schizophrenia in 1938. After chronic administration of ECT, the patient fully recovered.
Before ECT begins, patients are given a short-acting anaesthetic and a nerve-blocking agent, paralysing the muscles of the body to prevent them from contracting during the treatment and causing fractures. Oxygen is also given to patients to compensate for their inability to breathe. Then they receive either unilateral ECT or bilateral ECT. In unilateral ECT, an electrode is placed above the temple of the non-dominant side of the brain, and a second in the middle of the forehead. Alternatively in bilateral ECT, one electrode is placed above each temple. After this, a small amount of electrical current (approximately 0.6 amps) is passed through the brain, lasting about half a second. This produces a seizure that lasts up to one minute which affects the entire brain. ECT is usually give...
Epilepsy, also known as “seizure disorder,” or “seizure attack,” is the fourth most common neurological disorder known to mankind, affecting an estimated 2.3 million adults and 467,711 children in the United States. Unfortunately this disorder is becoming far more common and widespread worldwide. This staggering number of cases of people suffering from Epilepsy also involves an average growth rate of 150,000 new cases each year in the United States alone. Generally, many of the people who develop who are a part of the new are mainly either young children or older adults. Your brain communicates through chemical and electrical signals that are all specialized for specific tasks. However, through the process of communication, chemical messengers, also known as neurotransmitters can suddenly fail, resulting in what is known as a seizure attack. Epilepsy occurs when a few too many brain cells become excited, or activated simultaneously, so that the brain cannot function properly and to it’s highest potential. Epilepsy is characterized when there is an abnormal imbalance in the chemical activity of the brain, leading to a disruption in the electrical activity of the brain. This disruption specifically occurs in the central nervous system (CNS), which is the part of the nervous system that contains the brain and spinal cord. This causes an interruption in communication between presynaptic neurons and postsynaptic neurons; between the axon of one neuron, the message sender and the dendrite of another neuron, the message recipient. Consequently, the effects that epileptic seizures may induce may range anywhere from mild to severe, life-threatening ramifications and complications. There are many different types of seizures associa...
could be modified or expanded upon given what has been learned about the brain through
With this paper, we examined the literature on deep brain stimulation in order to answer the following questions: how does deep brain stimulation work in the treatment of Parkinson's disease, how effective is deep brain stimulation in treating Parkin...
Although brain or memory enhancing drugs, also known as ‘smart drugs’, are said to improve memory, however, no pharmaceutical compounds have been verified to be very effective over the long-term as a permanent solution. One of the potential alternative solutions to this is Transcranial Magnetic Stimulation (TMS). TMS guides a magnetic field at a particular part outside the skull to create feeble electric currents in the brain which help with some learning tasks. However, TMS has a limited reach which makes the hippocampus too deeply placed into the brain to be affected by TMS, making it efficient enough for areas just near the surface of the
For example, in Marshall Hall and Pierre Flourens’ exploration of the brain, they attempted to map out brain functions. While Hall was able to locate the root of voluntary and involuntary movement in the brain, Flourens assigned physical locations on the brain to different vital functions of the brain, including, but not limited to: auditory and visual reflexes, heartbeat, respiration, higher mental processes, and coordination. While Descartes’ was able to theorize about the functions of the brain as a whole, Hall and Flourens expanded upon his original theory and they revealed the functions of individual parts of the brain. Also exploring the brain, Franz Joseph Gall wanted to know whether or not the shape or the size of the brain could reveal something about a person or animal’s personality characteristics or intelligence. Gall attempted to “map the brain from the outside” (70), and his research reinforced the belief that specific brain functions could be generally localized. While Gall failed in his effort to map the brain from the outside, he was able to distinguish white or gray matter and to further Descartes ' evolving
Hall also found that the bodies voluntary and involuntary movements are located in certain regions with the brain and body. Hall’s contribution to the mind-body problem was in being able to show how the body can affect the mind and the mind effect the body by the voluntary (Mind) movements and the involuntary (body) movements. Flourens: Flourens work consisted of using the extirpation method. He destroyed animal parts, for the purpose of observing the brain and spinal cords. Through his work Flourens found the areas of the brain responsible higher mental functioning, sight and hearing of humans and the areas that control our coordination, heartbeat, respiration, and other important functions of the body. His contributions to the mind-body problem was to further dissect how the brain and to determine which exact areas of the brain affect the body. Gall: Gall was responsible for mapping the brain and he functions as well as he was able to confirm that the brain did have white and grey matter; nerve fibers connected to both sides of the brain and opposite sides of the spinal cord; fibers are connecting to both halves of the brain. Gall further contributed to the understanding of the mind-body problem by showing that it was possible to find specific brain functions in certain areas of the brain. Galvani: Galvani suggested that nerves were electrical and that if stimulated by electricity they would twitch. Galvani showed how the body can affect the mind and its interactions and reactions. Cajal: found the direction nerve impulses traveled in the brain and within the spinal cord. Cajal contributed to the mind-body problem by determining how impulses from the body can affect the brain. Weber: Weber is responsible for the two-point threshold which proved that the sensations of the body can
A Portuguese neurologist Egas Moniz experimented with the fact that, the frontal lobes led to psychiatric disease. Disrupting these connections could lead to a cure. He performed this 1935, he injected the white frontal lobes with alcohol. In 1949 he received the Nobel Prize for this new discovery. This new procedure spread like wild fire throughout the U.S. By 1950 286 hospitals were using this procedure on 18,000 patients.
(Johannes Muller, 2014). The doctrine of specific nerve energies was his most important contribution to the study of physiology of behavior. He observed that all nerves carry the same basic message, but we discern the messaged of different nerves not the same. Because of his doctrine of specific nerve, experiments were performed directly on the brain of animals, which was done by Pierre Flourens a French physiologist. This was knows as experimental ablation. There after he claimed to have found the part of the brain which was responsible for breathing, controlling heart rate, purposeful movements and auditory reflexes. Soon after this experimental ablation was applied to a human brain. This observation led to show that a portion of the cerebral cortex on the front part of the left side of the brain performs the functions that are necessary for speech. This remains important to the understanding of the brain. (Physiology of Behavior,
...ll human organs and the systems that they belong to. "This would be the most revolutionary type of alternative, especially for human related experiments"().