What Are The Ethical Issues Involved In Biomedical Research

Given the increasing complexity of current biomedical research involving ethical, technical, human, and administrative factors, ethics review committees have also had to evolve. Of course, none is perfect. However, the primary and occasionally unique objective of all of them is the protection of research subjects. Understanding this term as all individuals involved in a research project: patients, controls and researchers alike. This is a concept that is sometimes forgotten by the researchers themselves and it is common for them to feel uncomfortable with some of the opinions produced by the aforementioned committees. An unpublished analysis of the Institute's projects showed that the main reason why projects are not approved during the first

“The research regulations, the contributors consider such topics as risk-based regulation; research involving vulnerable populations (including military personnel, children, and prisoners); the relationships among subjects, investigators, sponsors, and institutional review boards”. (Lynch. 2014) This is a problematic false assumption that people tend to undertake, which creates fear and opposition to these beneficial investigations. Seemed as unethical, clinical trials are consistently repudiated by the IRB which is always protecting and keeping alive patients’ rights, although patients’ right are always present when an investigation is performed. There are certain general ethical principles considered and followed at every moment a clinical trial is performed to a group of patients. These ethical principles include autonomy, which is when it is required that people who are capable of making autonomous decisions in according to their beliefs, idiosyncrasies or perceptions are previously taken into account. The ethical obligation not to harm and maximize potential benefits in terms of research risks must be reasonable in the light of benefits: relevant objective, appropriate methodological design, to obtain some knowledge on health aspects. “Beneficence refers to the ethical obligation to maximize

They represent the design with the highest level of causality, where the researcher has control over exposure, are prospective, have the advantage that in theory biases can be avoided, they have a high level of population comparability (confusion) and information. Their practice, however, is very complex and in developing countries priority must be given, in addition to methodological aspects, to ensuring the rights of patients. However, on every occasion people hear “randomized clinical trials” the assumption of forced individuals to participate is always made. Randomized clinical trials is not choosing people out of nowhere and force them to participate, furthermore, is a long process of study trying to concur with all the needs required for the study to be successful. A failure to appreciate these risks could jeopardize the research effort. (Dresser. 2012) These false and negative assumptions are affecting the way clinical trials are seen by the community, generating more controversial arguments and causing review boards and institutions conduct new and extra strict regulations for investigators trying to find a