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A teratogen is an environmental agent such as a drug, chemical, virus, or other factor that produces a birth defect. Consuming alcohol while you are trying to get pregnant or already pregnant posses a very dangerous health risk for your unborn fetus. Alcohol is one of the most important teratogens that can cause a birth defect that will effect the developing fetus behaviorally, physically and cognitively. During your pregnancy the job of the placenta is to keep the teratogens from reaching the fetus, but the placenta is not always successful at doing this, which means the fetus will be exposed to some harmful teratogens. This also means that the timing and quantity of exposure to a teratogen is very crucial, especially during prenatal development (Feldman, R. S. (2013). Teratogens generally have the most significant effects during rapid development. For example, the sensitivity to a teratogen can be related to …show more content…
R., Decouflé, Pierre , & Hungerford, Daniel W. (1999). In addition, many different organ systems are sensitive to teratogens at different periods during development. For instance, the brain is most susceptible to teratogens between fifteen to twenty- five days after conception, while the heart on the other hand is most vulnerable to teratogens twenty to forty days after conception (Feldman, R. S. (2013). When talking about exposure time for a teratogen to be harmful to a fetus, many issues come to mind that promotes an unhealthy environment for your developing fetus. Such as, if you are living in poverty, and the mother is not able to afford things for her unborn baby to keep them healthy such as an adequate diet, or adequate medical care. This makes them more susceptible to various illnesses that can be harmful to the developing fetus, like
There are many factors that are integrated into the successful development of a child from Prenatal growth into toddlerhood. Teratogens (outside factors) have a great impact on the babies’ inutero development. Some outside factors like second-hand smoke, smog, or fumes from cleaning chemicals can cause negative effects on the child inside the womb. A few major affects from teratogens could result in low birth weight, head circumference, slow physical growth as well as an effect on mental, behavioral and motor skills (Berk, 2003). The environment around the mother provides many of these outside factors affecting the baby’s growth. But the main link to teratogens during the gestation period is most likely the mother. Daniel S. Messinger and the National Institute on Drug Abuse found that 2.8% of pregnant women admitted to using illicit drugs during their pregnancy (1996). Through illicit drug use, tobacco use and alcohol use, the mother disrupts her baby’s growth with possibly permanent damage.
Tobacco use during pregnancy is another environmental influence. The nicotine, carbon monoxide, and many other harmful chemicals mixed together in cigarettes are very harmful to the mother and especially the unborn child. This can cut off the baby’s oxygen supply, increase the risk of
The Centers for Disease Control and Prevention suggestion that a pregnant woman should not drink alcohol during pregnancy (Advisory on alcohol use in pregnancy 2005) has been widely criticized as being unnecessarily paternalistic, but the CDC goes further into explaining that, “Alcohol consumed during pregnancy increases the risk of alcohol related birth defects, including growth deficiencies, facial abnormalities, central nervous system impairment, behavioral disorders, and impaired intellectual development” (Advisory on alcohol use in pregnancy
The prenatal period is susceptible in terms of embryonic development, and some exposures to teratogens can have adverse and lifelong effects on a baby. Although physical outcomes resulting from teratogen exposure cannot be reversed, with hope, some of the behavioral effects of teratogens may have a decreased impact on the life of the child, though all mothers should pay special attention to the health of their child throughout their pregnancy.
Women who are pregnant, but drink moderate amounts of alcohol still pose many dangerous threats to their unborn child. A fetal alcohol effect is one of them, with slight deformities, mental retardation, and learning disabilities. Fetal alcohol effected children not only have physical differences from normal children, but also suffer with psychiatric problems and at more apt to get in trouble with the law. Pregnant women who drink not only run the risk of having a baby with fetal alcohol syndrome, but of having a child with alcohol-related neurodevelopmental disorder. Alcohol-related neurodevelopmental disorder occurs when children have prenatal exposure to alcohol. These babies have cognitive and behavioral problems that are alcohol-related, without the severe facial or growth deformities babies with fetal alcohol syndrome have. Pregnant women who drink expose their baby to teratogen ethanol- the active ingredient in alcohol. The fetus exposure is longer and more intense compared to the mother who is able to metabolize the teratogen ethanol.
Association of Placenta Preparation Arts board member Nikole Keller says, “the placenta is often referred to as a filter; this isn’t an ideal term for the placenta considering its function in the body… A more suitable way of looking at it would be as a gate keeper between the mother and the fetus. The placenta’s job is to keep the maternal and fetal blood separate, at the same time allowing nutrients to pass to the fetus, gas exchange to occur, and allowing waste from the fetus to pass through the mother, . The placenta does prevent some toxins from passing through to the fetus but they are not stored in the placenta. Toxins in the body and waste from the fetus are processed by the mother’s liver and kidneys for elimination”
Teratogens are defined as “those substances which exert an adverse influence on development [of a developing fetus]” (Hepper, 2007, p. 48). Teratogens can be environmental influences, such as chemicals or infectious agents. They can also be physical conditions or nutritional deficiencies present in the mother. Thousands of known teratogens have been discovered. For example, Purdue University’s Department of Radiological and Environmental Management (2014) maintains an internet-based list of teratogens which currently names over 2000 substances. This paper will discuss two of these teratogens in further detail: maternal cigarette smoking and vitamin A.
The affects teratogens can have on the developing fetus can vary greatly. Research provided from the University of Iowa’s on teratogens explains some of the possible outcome to exposure to certain teratogens. Listed birth defects resulting from exposure to teratogens, range from prenatal death, to physical and mental abnormalities.
In 2006, 49% of all pregnancies in the United States were reported unintended on a national survey.1 The highest rate of preventable birth defects and mental retardation is due to alcohol use.2 In this paper, I will further discuss FAS, the potential effects of binge drinking during the embryonic stage of gestation, and what actions need to be taken in order to reduce the incidences of alcohol-related birth defects. Alcohol Consumption During Pregnancy Alcohol is an ethanol containing substance that is a common beverage in many social and private settings. Alcohol is also a teratogen, therefore alcohol consumption and binge drinking potentially pose a substantial risk to the embryo or fetus. In 2013, the Centers for Disease Control conducted a telephone survey of women in the age range of 18-44 years regarding alcohol use.3
There are a few different ways that mothers and fetuses can be exposed during this sensitive time. They can be exposed accidentally, knowledgably, or with no knowledge of the pregnancy. An example of an accidental exposure is a radiation accident, like Chernobyl. There was no way to record the actual dosage of radiation that each child received in utero, or the amount of women who had spontaneous abortions after being exposed to the accidental radiation. It has been shown that those babies “exposed during the most sensitive period of pregnancy performed less well [on verbal IQ tests] than those who were exposed after week 16 of pregnancy” (Heiervang 213).
During recent years, numerous newspaper and magazine articles have suggested that humans may be at risk because small amounts of well known environmental contaminants, such as dioxin, PCBs and DDT, can affect hormone levels. Hormones are produced by the endocrine system as regulators of biological function in target organs. Because hormones play a critical role in early development, toxicological effects on the endocrine system often have an impact on the reproductive system. The term endocrine disruptor is used to describe chemicals that can mimic hormones and may either enhance or counteract their effects. It has been suggested that these hormone changes can, in turn, lead to a variety of health problems including cancer, decreased fertility, and abnormalities in newborns.
Jancárková, N., & Gregor, V. (2000). [Teratogens during pregnancy]. Ceska gynekologie/Ceska lekarska spolecnost J. Ev. Purkyne, 65(3), 188-194.
Another study measured the levels of flame retardants in both mothers’ prenatal and their children’ serums, and found that high concentrations of flame retardants like polybrominated diphenyl ethers were associated with a poorer attention than normal, slower cognitive development, and motor coordination difficulties. (Hamers, 2017)
(Gilman, Breslau, Subramanian, Hitsman, & Koenen, 2008). Despite the warnings about the dangers of smoking while pregnant, some women still choose to smoke, which places themselves and their baby at risk for many health issues. Damage caused by smoking while pregnant During pregnancy, smoking can cause problems for a woman’s own health, including, ectopic pregnancy, vaginal bleeding, placental abruption, in which the placenta peels away, partially or almost completely, from the uterine wall before delivery; Placenta Previa, a low-lying placenta that covers part or all of the opening of the uterus (March of Dimes, 2011). Women that smoke expose their unborn baby to dangerous chemicals, like carbon monoxide, tar and nicotine.... ...
In recent years it has become clear that some environmental chemicals can cause risks to the developing embryo and fetus. Evaluating the developmental toxicity of environmental chemicals is now a prominent public health concern. The suspected association between TCE and congenital cardiac malformations warrants special attention because TCE is a common drinking water contaminant that is detected in water supplies throughout the U.S. and the world. There is a lot of concern about the clean up of toxic pollutants from the environment.