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Stem cells and their types essay
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Nowadays, there are many alternatives or any other methods to improve the healthcare especially in a transplantation world. There are few choices available for the people today such as the embryonic stem cells, bone marrow stem cells, peripheral blood cell and the most new is the umbilical cord blood. The umbilical cord blood (UCB) defined by Chima and Mamdoo (2011, p. 79) as the blood which taken from the cut umbilical cord attached to the placenta of a newborn baby after a delivery. It been stated (Chima and Mamdoo 2011, p. 79) that the cord derived from the allantois have a rich source of multipotent stem cells, including the CD34+ , CD38- and haematopoietic progenitor cells. This shows that the cord blood could be more potential as the bone marrow cell in the patients with the haematological or non-haematological problems. The first successful umbilical cord transplantation done was in 1989 in a child with a Fanconi’s anemia and since then, the growth or demand for the cord blood increased. As we can see, this contributed to a major reason for the need of umbilical cord blood donation, storage, processing, freezing, and releasing of cord blood to the patient. Thus, establishment of the cord blood bank (CBB) because of the demand increased (Ballen 2010, p. 8). As mentioned by Ballen (2005, p. 3786), the first establishment of cord blood bank was in the early 1990s in New York, Milan, and Dusseldorf. The storage of the cord blood could last for about 15 years (Fadel 2006, p. 1). The point is that there are many ethical and legal issues raised by this CBB that need clarification and justification like the informed consent, ownership and property rights, collection of cord blood, and public CBB vs private CBB.
As mentioned earlier, there are issues on informed consent but what is actually the informed consent is all about and what is the thing that need to be considered for this cord blood banking. Firstly, what is mean by informed consent is the permission given from someone of one behalf to another behalf. According to Petrini (2010, p. 140), there were some kinds of elements of process leading to informed consent found by Beauchamp and Childress. The first one is the threshold elements (preconditions) which to understand and decide. Second, the information element, which means to make things clear or clarify the information given, the good recommendation of plan and to understand the previous elements.
Medical researchers utilize this versatility to develop treatments for incurable diseases. Despite the considerable benefits of stem cells in medical applications, the use of some sources of stem cells is not ethical. In article 1761 of the Catholic Catechism, the church teaches "One may not do evil so that good may result from it.” The good of medical discoveries does not justify the evil of killing to obtain the stem cells. Therefore, people have a moral obligation to restrict the use of ethically collected stem cells such as those from umbilical cords or adult bone marrow. Stem cell research has potential to cure many diseases. However, in order to conduct ethical research, scientists must limit refrain from using fetal and embryonic stem
In most hospital delivery rooms, the doctors will routinely clamp and sever the umbilical cord with in fifteen to thirty seconds of the mother giving birth. When clamping the cord, the doctors will clamp the cord in two places, one close to the infant and then again in the middle of the cord another clamp. By delaying the clamping, fetal blood in the placental transfusion can provide the infant with an additional thirty percent more blood volume and up to sixty percent more blood cells (McDonald, S., & Middleton, P., 2009). This reduces the risk of the hemorrhaging that could occur after birth. But with new ongoing studies, it is said that by delaying the clamping of the cor...
Research on human fetal life involves numerous complex medical, moral, and legal aspects. It is not always easy, nor desirable, to seal off one aspect from another. Both sides of fetal tissue use will be equally focused on as a moral issue. The topic is a timely and important one because research on human fetal life is reportedly a growing industry and the subject of legal developments both in the United States and around the world.
There is very much controversy surrounding the case of the very popular Henrietta Lacks. One of the major implications on the situation that people have a problem with is the lack of consent obtained by Johns Hopkins University and the doctors involved. All though it was not common place as it is in today’s society, many feel that it was not ethical to perform medical procedures without the patient and their family being given all of the knowledge regarding the situation. The tissue sample taken by doctor Howard W. Jones was unbeknown to the family which violates the ethical respect for the person that should be held. A sample of someone’s DNA is not anything that should be taken lightly or regarded as unimportant. It should have been a decision made by Henrietta, and had she of known of the procedure she may have voted against donating to research. This lack of incorporating Henrietta and her family caused there to be a dismal amount of respect for persons shown by the University and all
According to Courtney Farrell’s overview of stem cell research, stem cells are undifferentiated cells that can be used to fix and replace other kinds of cells that are missing or damaged, and they can be derived from several different sources. The first of these sources, “embryonic” stem cells have been the source of many ethical debates because the process to gain embryonic stem cells involves the destruction of a human embryo in its early stages. Many people find this unethical and think it’s equal to human murder. According to the article by John Pearson, other types of stem cells include adult stem cells, which can be derived from bone marrow in grown adults, and umbilical blood stem cells; these are found in the blood of the umbilical cord after the birth of a baby and are becoming a great replacement for embryonic stem cells.
Stem Cells: What, How and Why? Stem cells are infinitely valuable when considering their potential applications in the medical profession. While current legislative restrictions have halted the development of new ?stem cell lines? to any agency or company that receives any form of governmental grants, there is no question that the medical profession is standing at the brink of a new era of technological advancements in healthcare and research.
The umbilical cord has a vital role in keeping babies alive in the womb but could help cure a range of diseases and injuries (2010, Weaver). The umbilical cord contains a rich souse of stem cells, which are valuable because they can regenerate and fix human tissue. Some cells also have the ability to turn into different types of cells. Scientist believes with these ‘master’ cells they will be able to treat a wide range of disorders such as cancer, auto-immune diseases and arthritis. Storing the cord blood of new born babies could be a lifesaver to children’s that may become sick in their young age or it may just be a waste of money in the end, with currently only 1 in 41,000 (1% ) Australian mothers have chosen to bank their child’s cord blood.
On April 28, 2011 - the United States Appeals Court overturned the rule of a federal judge because of several issues that emerged with stem cell research being funded by the government. Although, the science of human embryonic stem cell is in its initial stages - there is much hope for scientific advancement due to the ability for human embryonic stem cells to grow into virtually various kinds of cells Favorably, advocates for stem cell research and pharmaceutical companies strongly believe that stem cells may pave a way to discover new methods of treatment for devastating ailments; such as, Leukemia, Alzheimer’s disease, Heart disease, Parkinson’s disease and diabetes- a prospect that is inspiring to both scientists and those who are seeking cures for themselves and family members. In contrast, numerous pro-life advocates are against federal funding for stem cell research because of the method in which these stem cells are extracted. In addition, several other groups argue that the federal government has abandoned more substantial as well as promising and less controversial adult and cord stem cell research. Instead, the government has dedicated a majority of their funding in favor of the more popular and controversial stem research. Ultimately, as long as humans exist - the need for a more extensive and technological progress will be abundant and crucial to humanity's survival. However, does the needs of the human species outweigh the potential lives embryos represent? With so much on the line, let us explore exactly what human embryonic stem cell (HESC) research is and what may be potentially weighing in the balance for the human race if we proceed down this road.
The New England Journal of Medicine (2005) states that a Cord Blood Transplant is when the blood from a newborns umbilical cord is taken and given to another infant. Healthy umbilical cord blood is new and has little to none bacteria or diseases that could harm someone. Usually the placenta and umbilical cord is thrown out, but in recent research it is found that the blood from the umbilical cord and placenta can help prevent or slow down Krabbe Disease. According to Escolar, Yelin, & Poe (2006) about 90% of the children that were used in their study for
Stem cells offer exciting promise for future therapies, but significant technical hurdles remain that will only be overcome through years of intensive research. Stem Cells have the incredible potential to develop into many different cell types in the body during early life and growth. Scientists primarily work with two kinds of stem cells from animals and humans. The embryonic stem cells and the non-embryonic stem cells. Stem cells are the cells from which all other cells originate. In a human embryo, a large portion of the embryo’s cells are stem cells. These stem cells can be used for cell-based therapies. Cell-Based therapies are treatments in which stem cells are induced to differentiate into the specific cell type required to repair damaged or destroyed cells or tissues. Stem cells are versatile and offer the possibility to treat a number of diseases including Alzheimer’s, stroke, cardiovascular disease, diabetes, etc. The problem is that for the process of embryonic stem cell research and embryo will be destroyed if used. This raises a moral issue and questions of whether stem cell research is unethical or not.
Neonatal resuscitation is intervention after a baby is born to strengthen it’s breathe or to boost its heartbeat. Approximately 10% of neonates require some assistance to begin breathing at birth, but only 1% require serious resuscitative measures. Informed consent regarding neonatal resuscitation is a constant ethical debate. This discourse ordinarily occurs between doctors and parents; parents often feel that the decision has been made for them, believing that they were not fully informed of any consequences that may occur before making their final action plan, or thinking that their opinion was not taken seriously; however, doctors see the procedure in a different light, that the parents can’t choose the best option for the child regardless of counseling, or performing as the parents wished but believing that the result could have differed if the parents had known all the effects that it will have further down the line, or convinced that they would have made a better
In conclusion, obtaining informed consent is a vital part of respect for the patient and safeguarding of self-determination. The consent to participate in research or treatment should be informed, comprehensible, and free of coercion. There is not a clear black and white answer because no matter what is done to assure informed consent there is always a moment of doubt on the end of the patient as to whether what is going to take place is fully understood and their true wishes honored.
Background Info? Bone marrow transplantation restores stem cells that were destroyed by high doses of chemotherapy and/or radiation therapy.
The idea behind this is that no harm is coming to the fetus or the mother in the case of a stillborn or a miscarriage or the use of cord blood. The umbilical cord is detached from the infant right after birth therefore using the cord blood and those stem cells would also not cause any harm to the infant. Stem cell research becomes unethical when fetuses are being aborted for the purpose of the stem cell research, this is not only risking the mother but also killing a human being (the
The article titled “Contemporary Ethical Analyses: A Shortfall in Scientific Knowledge” describes the ethics through the public’s eye. One of the major ethical issues brought up is informed consent.