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Recommended: Stem cell research
Looking back on 2010, I wanted to share with you a snapshot of the incredible progress that has been made this past year in terms of stem cell science and regenerative medicine.
This year enabled scientists to share their incredible findings worldwide, ranging from discoveries within their labs through to the successes of numerous clinical trials. What made these successes more relevant were the amazing stories that were told by people from all walks of life who participated in adult stem cell case studies, s/cell therapy and treatments. They have (with the help of the internet) been able to share their incredible experiences showing us first hand the benefits and progress they achieved in a very short time.
2010 was a truly remarkable and
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from Wayne State University addressed the U.S. Senate Subcommittee on Labor, Health and Human Services, and Education. Jean Nelson is a neuroscientist who is doing incredible work on bringing forward adult stem cell treatments, particularly for those with spinal cord injuries, head injuries and radiotherapy damage. In her speech she referred to "the brave pioneers who first explored the potential of adult stem cell treatment. The progress of adult s/cells has now gone far beyond these particular patients (as noted below) allowing long term follow up results of numerous patients in peer reviewed published clinical …show more content…
[As reported on BBC News - Wednesday 5 May 2010]. The trials, which are thought to be a world first, are taking place at Frenchay Hospital in Bristol, England. Clinical trials on six multiple sclerosis (MS) patients who have had s/cell injections have produced "encouraging" results, scientists say. The six were injected with s/cells harvested from their own bone marrow. Research found this increased nerve function by up to 20%. Professor Scolding said he was encouraged by this early study, the data from which may indicate that s/cells can stabilize MS. The team is planning a much larger trial of the technique. 'My long-term hope is that s/cell research will be a cure for MS and will be available for everyone who is afflicted with this disease' says Liz Allison, an MS sufferer. "A large study is required to assess the effectiveness of bone marrow cellular therapy in treating
“What are the potential uses of human stem cells and the obstacles that must be overcome before these potential uses will be realized?” . InStem Cell Information. Bethesda, MD: National Institutes of Health, U.S. Department of Health and Human Services, 2009.
Multiple sclerosis (MS) is a disease affecting the myelination of the central nervous system, leading to numerous issues regarding muscle strength, coordination, balance, sensation, vision, and even some cognitive defects. Unfortunately, the etiology of MS is not known, however, it is generally thought of and accepted as being an autoimmune disorder inside of the central nervous system (Rietberg, et al. 2004). According to a study (Noonan, et al. 2010) on the prevalence of MS, the disease affects more than 1 million people across the world, and approximately 85% of those that are affected will suffer from unpredictably occurring sessions of exacerbations and remissions. The report (Noonan, et al. 2010) found that the prevalence of MS was much higher in women than in men, and that it was also higher in non-Hispanic whites than in other racial or ethnic groups throughout the 3 regions of the United States that were studied.
“Stem Cell Research: Guide to Critical Analysis.” Points Of View: Stem Cell Research [serial online]. January 2013;:4. Available from: Points of View Reference Center, Ipswich, MA. Accessed November 26, 2013.
Around the world, many people are living with neurologically debilitating disorders like multiple sclerosis. Multiple sclerosis is best described as a pathological “inflammatory-mediated demyelinating disease of the human central nervous system,” and affects more than 2.5 million people globally (Trapp & Nave, 2008).
Bone marrow is the flexible tissue in the interior of bones. Hematopoiesis is when the red blood cells are formed by cores of bone marrow in the ends of lengthy bones. Bone marrow comprises 4% of the total of a person’s body mass. Bone marrow transplants treat severe diseases of the bone marrow, including specific forms of cancer. And so many people don’t receive the proper transplant they need. Paying people for their bone marrow would help to solve that situation but it’s harmful for the patience, unethical, and could potentially be risky for donors.
1989 came with a boom as it molded the course of history – The Galileo Spacecraft launched by NASA flew up, the Berlin Wall tumbled down, and the massacre of Tiananmen Square left the city of Beijing in turmoil. Interestingly, a lesser known event swung the world of science in a complete 180. Scientists used embryonic stem cells to fabricate the first mice ever to lack assigned genes (Making). Just over a decade later, and following numerous embryonic stem cell discoveries, former U.S. president George W. Bush, authorized the use of federal funds for limited human embryonic stem cell research (Human). So, aiming for progress, mankind launched this new and exciting expedition. Nonetheless, in a culture that so readily promotes whatever promises a brighter future without weighing the means, we need to recognize the immorality of HESC testing. By exploiting these tiny humans in their foremost stages of development, the scientists behind this commit a heinous crime –
Scientists would be able to grow spinal cells from pluripotent stem cells. These cells could possibly repair spinal cord damage. Those afflicted by paralysis, such as Christopher Reeve, could possibly move again. Stem cells could also be used to grow nerve cells, possibly combating Parkinson’s disease or Alzheimer’s. While it will be many years before scientists may actually be able to find a way to combat these diseases, there is a great promise in stem cells.
Imagine that there is a cure for nearly every ailment that affects the human race. Imagine that you could help the terminally ill, put those you love out of pain, and cut the healing time of an enormous number of serious illnesses in half. Imagine a world in which pain and suffering would be nearly nonexistent, and the people you love can live safe from the fear of crippling injury. Now what if I told you that this utopia was a fast approaching reality? Everything from serious life threatening burns to lymphoma, AIDS, Alzheimer’s, Muscular Dystrophy, Parkinson’s Disease, Spinal Cord Injury, and Strokes could, in the very near future, be eliminated through the simple culturing and implementation of stem cell therapy . These diseases are no small component of the myriad of conditions that plagues the human race, and yet, the end for these horrible maladies could very well be in sight. Man has always sought to end suffering, largely without success, until now. the promise that stem cell therapy holds could completely change our world for the better. Already, stem cell therapy is being used to treat leukemia, immune disorders, hodgkins and non-hodgkins lymphoma, anemia and a profusion of other ailments. As you all know, this is no small accomplishment. One day i believe that we may look at alzheimer's and diabetes and other major illnesses much like we look at polio today, as a treatable illness. Right now, our research with stem cells is providing us with new light into how we look at and model disease, our ability to understand why we get sick and even to develop new drugs. In 2008, a researcher from the New York Stem Cell Foundation Laborato...
Primarily, the term MS refers to a chronic disorder that attacks the central nervous system (CNS). It is most common in temperate continents such as Europe and Australia with Asiatic and African continents having a lower risk of the disease (Wiley Online Library, 2013). A search organised by the Multiple Sclerosis Society (2013) has estimated that there are 127,000 people living with MS in the United Kingdom. Further research by Chipps, Clanin, and Campbell (1992, pp. 158-167) shows that MS disorder more likely affects women than men with its symptoms occurring between the ages of 20 and 40 in most cases and is quite uncommon in childhood and old age. The nerve cells known as neurons in the brain constantly transmit and receive signals. They invoke emotions, activities and cognition that constitute the day to day experiences of humans. Under normal circumstances, these signals travel on a protected insulation path known as the myelin sheath. This insulation is vital as it enables signals to reach their target. In Multiple Sclerosis, the myelin sheath gets disintegrated causing the nerve fibre to be damaged leading to a disruption in the abili...
Stem cells are an ongoing research project in which new discoveries are being made about them, and researchers are learning how to use them in new ways. The three current kinds of stem cells all prove to have their own challenges when it comes to using them. The important thing is finding out which stem cell is right for the patient and how much of an ethical concern there is when it comes to using the stem cell. As we learn the best way to use them and they become more popular in the medical field, stem cells will become a new weapon in the fight against certain diseases.
... resulting impairment to the CNS. The first group of mice exhibited a pattern of CNS inflammation that resembled that of the most common subtype of MS, RRMS, with lesions filled with macrophages, a type of immune defender cell. The second group of mice displayed inflammation deep in the CNS tissues and in the optic nerve with lesions filled with neutrophils, another type of immune cell. Both groups of mice were given antibody drugs similar to drugs being developed against MS in humans. The effects were observed over time and results showed that some of the drugs inhibited disease in the first group of mice but did not inhibit disease in the second group. Thus, as Mark Kroenke (2008), the study’s first author and a Ph.D. student in immunology at U-M stated, "That's our proof that these really are different mechanisms of disease" (Kroenke et al., 2008).
Physical and occupational therapy may also help. Multiple sclerosis is not a fatal disease. Most people with MS have a normal or near-normal life span and usually die from the same conditions that affect general population (heart disease, cancer). Multiple Sclerosis symptoms can negatively affect the quality of life. Suicide rates among patients with multiple sclerosis are higher than average. The majority of patients with MS do not become severely disabled. Women tend to have a better outlook than men. MS has long been known, yet diagnosis remains difficult due to the complexity of the disease and its wide array of signs and symptoms. Treating MS still relies on symptomatic relief, but therapeutic advances in the form of DMDs have shown promising
“Top Ten Things to Know About Stem Cell Treatments.” Www.closerlookatstemcells.org ISSCR. Web 1 November 2013
It is clear that Multiple Sclerosis is a dreadful disease. Its multiple variations not only induce neurological debilitation but it can also bring about other disorders. Unfortunately, a cure hasn’t been created yet but medications and a healthy lifestyle can make the victim’s life much easier.
Specific Purpose Statement: To inform the audience about the criteria for becoming a blood donor