St. John’s Wort for Depression

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Introduction

In our culture we seem to have the idea that if we pop the right pill, our dissatisfaction or discomfort will be assuaged. Lately, herbal drugs have become very popular as alternative medicines. They are purported to heal everything from memory problems to sexual dysfunction. One of the most common and most controversial herbal remedies is St. John’s Wort. As a cheap over-the-counter antidepressant, and with over 17% of the population experiencing depression sometime in their lifetime, its allure to the lay person is not surprising (Kessler, R. C. et al., 1994). Is St. John’s Wort an effective treatment for depression as many claim it is? Is it really safe?

St. John’s Wort, often called hypercium for its botanical name, Hypercium perforatum, is derived from a yellow flowering plant. Hypercium is native to Europe, western Asia, North Africa, Madeira and the Azores, and has been transported to and grows wild in parts of Australia and North America (Cracchiolo, 1999). Extracts of the plant have been used in European folk medicine for centuries (Kim, 1999), and in Germany today, Hypercium is used above all other antidepressants (Volz, 1997). Hypercium can be taken through infusion, powder, tincture, fluid extract, or oil, and because there is no standardization, doses range from 0.4mg to 2.7mg, and 300-1000mg of crude extract per day (www.frontiercoop.com/herbfest/98/notes/snjwort.html ).

Advertisements and Other Web Sites About St. John’s Wort

Hypercium has become popular in the United States because of its scientifically documented antidepressant properties with much of the evidence coming from European countries . Because the FDA has not approved Hypercium for any medical purpose, there are many varying reports of its effectiveness (Cracchiolo, 1999). The said effectiveness often seems to be correlated with the purposes of the reporting organization, and therefore, any information about hypercium should be regarded with caution.

The most dramatic reports of the efficacy of the herb come from commercial organizations that are trying to make a profit. Vital Source, www.intellex.com/~gilbert/johnwort.html, claims that Hypercium is the most thoroughly researched natural antidepressant available. While Hypercium may in fact be the most thoroughly researched natural antidepressant, one must consider the number of other natural antidepressants there are. There are very few, if any, and this advertisement seems to suggest to the reader that because there has been so much research, it is a safe drug to take. The advertisement goes on to say that Hypercium relieves anxiety, apathy, sleep disturbances, insomnia, anorexia, and feelings of worthlessness with no dangerous or long term side affects.

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