Spinal fusion stabilizes the spinal vertebra by fusing the disk spaces between the vertebra. The purpose of Lumbar fusion surgery is designed to help create solid bone between the adjoining vertebra. Classically Autograft bone has been used for fusion. This case study demonstrates the successful use of a synthetic bone graft called Signafuse. Signafuse is a moldable bone graft comprising a proprietary combination of patented bioactive glass particles and biphasic mineral granules suspended in a patented resorbable polymer carrier.
Introduction: The purpose the study is the presentation of successful use of Signafuse Bone Graft Putty in vivo. Fusion Products are commonly used in the field of Orthopaedics. They serve an important role as far as relieving pain and treating morbidities.
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An allograft is either bone, cartilage, tissue, ligament, tendon or any section of the skin that is donated from another person that is deceased. Allografts do contain osteoconductive scaffolds with minimal osteoinductive factors. A disadvantage of Allografts is the risk of bacterial contamination or the possibility of viral transmission diseases such as hepatitis and human immunodeficiency5. Jorgenson et al.6 Conducted a prospective analysis in lumbar fusion of allografts versus autografts in the same patient and concluded that an ethylene oxide-treated allograft is inferior to an autograft and should not be used for posterior lumbar fusions(Level II). Further, An et al.7conducted a prospective comparison of autografts and allografts for adult posterolateral lumbar spinal fusion and reported that autografts resulted in significantly greater bone density, followed by the mixture of autografts and allografts, frozen allografts, and freeze-dried allografts (Level II). These reports indicate that allografts alone were not able to achieve a sufficient fusion rate for posterior spinal fusion in the adult
Papa J. 2012. Conservative management of a lumbar compression fracture in an osteoporotic patient: a case report. J. Can. Chiropr. Assoc:29-39
Recent research has been focused on distinguishing the most successful augmentation surgery for restoring deficient bone (4, 16-18). Surgical techniques and survival of the bone graft has been vastly highlighted in the literature. ,However, the importance of recipient site on success rate of augmentation procedure has been less issued (16).
Spinal Muscular Atrophy, also known as “SMA” is a genetic and also a motor neuron disease that affects the area of the nervous system that controls your voluntary muscle movements such as walking, crawling, and swallowing. When someone acquires this condition their muscles start to shrink as a cause to the muscles not receiving signals from the nerve cells in the spine that control function. Spinal Muscular Atrophy is a rare but serious condition.
In orthopedic surgery, iliac bone graft which is commonly used for treatment nonunion or spinal fusion is contained multipotential stem cells or mesenchymal progenitor cells. These cells are found approximately 1 in 10,000 nucleated cells in the bone marrow. Friedenstein et al. (1970) reported that a rare population of cells was found by plastic-adherent ability (Friedenstein et al., 1970). These cells are capable of proliferation and mesenchymal lineages differentiation (Pittenger et al., 1999, Caplan, 1991). Unique antigens of MSCs (hMSCs) are controversy and the limited popularity of sorting cells techniques are not as widely used as gradient media in MSC isolation. Most MSC populations have been isolated by plastic adherent ability which is similar to that originally used by Friedenstein. Direct BM plating method is commonly used for cells from small animal (Lennon and Caplan, 2006, Nadri et al., 2007) but in human bone marrow, Density gradient centrifugation is the most commonly used method for isolating MSCs.
Alumina and zirconia ceramics have been widely used in orthopaedic hip replacements for the past 30 years. The advantage of using these was lower wear rates than those observed using polymers and metals. Because of the ionic bonds and chemical stability of ceramics, they are relatively biocompatible and therefore more preferable to use than metals and polymers. Alumina is most commonly used as a femoral head component instead of a metal in a hip prosthesis because this would reduce the polyethylene wear that is generated. Alumina is a desirable biomaterial to use in hard tissue implants because of characteristics like excellent wear resistance, high hardness, bio inert, low abrasion rate and good frictional behaviour. Furthermore, it has excellent surface finish as well as high fatigue streng...
What is scoliosis? Scoliosis is a musculoskeletal disorder that causes the back to curve sideways like and “S” or a “C” and cause the body to lean to one side. Scoliosis can eventually if not looked into and not treated colid with your bodily organs like your heart, lungs, and kidneys. This can cause you to slump down into a hump and cause it hard to breath and do physical activity.
Selby PL, Davie MWJ, Ralston H, et al. Guidelines on the management of Paget’s disease of bone. Bone. 2002; 31: 10-9.
“The doctor of the future will give no medication, but will interest his patients in the care of the human frame, diet and in the cause and prevention of disease” by Thomas A. Edison. Chiropractors use hands-on spinal manipulation and other alternative treatments on the spine which will enable the body to heal itself without surgery or medication. Chiropractic care began in 1895 when its founder, Daniel David Palmer, claimed any and all diseases could be healed by nothing more than just his hands. Dr. Palmer examined a janitor who was deaf for 17 years after the janitor felt his back was out of place, so Dr. Palmer gave an adjustment to what was felt to be a misplaced vertebra in the upper back. The janitor then observed that his hearing improved thanks to Dr. Palmer. Chiropractors use manipulation to restore mobility to joints restricted by tissue injury caused by sitting without proper back support. Chiropractic is primarily used as a pain relief alternative for muscles, joints, bones, and connective tissue, such as cartilage, ligaments, and tendons. About 22 million Americans visit chiropractors annually
A femoral head preserving operation having satisfactory results in long term follow up should be the treatment of choice in younger individuals and THR in elderly where femoral head is badly damaged and in younger patients with multisystem diseases and poor general health. Considering the life style of people of our country who needs squatting habit, decompression of femoral head and TFL muscle pedicle bone grafting is a good option both in early and even in advanced stages of the disease unless the femoral head is badly deformed or collapsed more than 5mm. Considering its technical simplicity compared to the use of other vascularised bone grafts like vascularised fibular or vascular pedicle iliac crest graft, the above method can be recommended in patients of developing countries like ours where osteonecrosis is common.
Osteoporosis is a condition, which advances with age, resulting in fragile, weak bones due to a decrease in bone mass. Externally osteoporotic bone is shaped like normal bone, however it’s internal appearance differs. Internally the bone becomes porous due to a loss in essential minerals, including phosphate and calcium. The minerals are loss more quickly than they can be replaced and in turn cause the bones to become less dense and weak. The bones become prone to fracture, due to their weakness. Therefore the awareness of the disease tends to occur after a fracture has been sustained. The bones most commonly affected are the ribs, wrist, pelvis and the vertebrae.
Bone tissue engineering (BTE) plays an important role in treating bone diseases related to osteoporosis and other orthopedic treatments. Although several methods are used in orthopedic surgery, some bone transport methods such as autografting and allografting have a certain number of disadvantages. Both are expensive methods and they can be exposed to infections and diseases. Therefore, in stead of using these potential risky methods, bone tissue engineering process are used to treat in orthopedic treatments. In general, both tissue engineering and bone tissue engineering have major constituents including stem cells, scaffold, bioreactors and growth factors.
The syndrome is caused because of Genetic mutation that replaces connective tissues (muscles) with bones when someone gets injured instead of getting cured. This results in a new skeletal structure. Unfortunately this syndrome does not have any cure and the patients are advised to always be careful and not to fall or have any kind of traumas. They can’t engage in any sports in order to prevent any injuries. Surgery for removal of extra bones is not an option because removal of bones will lead to ingrowth of more bones. From previous cases it is seen that most of the patients suffering from this condition do not live more than 40 years and they die of respiratory
Based on the findings presented, Dr. Green made the correct diagnosis in predicting that this gentleman had a spinal cord injury.
Sharp, J., Frame, J., Siegenthaler, M., Nistor, G., Keirstead, H.S. (2010). Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cell Transplants Improve Recovery after Cervical Spinal Cord Injury: Stem Cells, 28, 152 – 163.
Starting my freshman year at County High School, I played basketball and loved every minute of it. I wouldn’t be conceited enough to say I was good, but God did bless me with the talent to play. My life revolved around the sport of basketball; some would say I slept, ate, and breathed every part of it. I spent all my time training and practicing to make myself a more dedicated athlete. This dedication not only helped me as a player, but also molded me into the person I am today. It somehow helped to prepare me for what defeat I would face with back surgery in the future.