Benzedrex (Propylhexedrine) Classification: Vasoconstrictor (Broad) Molecular Weight: 155.285 g/mol pka: 10.61 Molecular Formula: C10H21N IUPAC Name: 1-cyclohexyl-N-methylpropan-2-amine Description Benzedrex is used to provide provisional relief to persons suffering from nasal congestion due to allergies, colds, and allergic rhinitis. This drug contains inactive ingredients menthol and lavender oil. Propylhexedrine was a schedule V drug int United States but was removed and listed as unscheduled after Dec. 3rd 1991. Propylhexedrine is an alpha-adrenergic agonist that is a slightly water-soluble compound. Propylhexedrine also comes as a hydrochloride salt in a crystalline form and presents many of the physical properties of Propylhexedrine. …show more content…
Mechanism of Action Propylhexedrine is a TAAE1 agonist and targets two known proteins synaptic vesicular amine transporter and trace amine-associated receptor 1. Synaptic vesicular amine transporter is a protein that is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Trace amine-associated receptor 1 is a receptor for trace amines. The drugs main method is as an alpha beta-adrenoceptor agonist, which causes
Alcohol, which is the nucleophile, attacks the acid, H2SO4, which is the catalyst, forming oxonium. However, the oxonium leaves due to the positive charge on oxygen, which makes it unstable. A stable secondary carbocation is formed. The electrons from the conjugate base attack the proton, henceforth, forming an alkene. Through this attack, the regeneration of the catalyst is formed with the product, 4-methylcyclohexene, before it oxidizes with KMnO4. In simpler terms, protonation of oxygen and the elimination of H+ with formation of alkene occurs.
... middle of paper ... ...gical or physical dependence. Once injested, Adderall inhibits the function of monamine transporters by lodging into the transmitter and blocking it off. The main function of these monamine transporters is the re-uptake and recycling of catecholamine neurotransmitters.
Spironolactone is a light cream colored stable powder that has a faint odor (6). Spironolactone was created by G.D. Searle and is currently the only product that directly treats hyperaldosteronism, the excess production of aldosterone in the body (9). Spironolactone is in the aldosterone-receptor blockers medication category. Spironolactone is a diuretic mostly used to treat hypertension and edemas (8). The discovery that led to the development of spironolactone was aldosterone being found to be the third hormone in the adrenal cortex (6). Aldosterone is created in the zona glomerulosa that is a region of the adrenal cortex. The information know aldosterone led to research into the creation of compounds and medications
8. Gillard, M., Chatelain, P., & Fuks, B. (2006). Binding characteristics of levetiracetam to synaptic vesicle protein 2A (SV2A) in human brain and in CHO cells expressing the human recombinant protein. European Journal of Pharmacology, 536(1–2), 102-108. doi: http://dx.doi.org/10.1016/j.ejphar.2006.02.022
The Role of Dopamine Receptors in Schizophrenia. Retrieved March 3, 2005, From Stanford University, Chemistry department web site, http://www.chem.csustan.edu/chem44x0/SJBR/Mann.htm Naheed, M., & Green, B. (2000). Focus on Clozapine. Retrieved February 7, 2005. From http://www.priory.com/focus14.htm Waddinton, J.L., & Buckley, P.F. (1996).
PhenRx is comprised of a 377 mg proprietary blend containing 137 Trimethylxanthine, Synephrone HCL, Schizandrol, Beta Phenylethylamine, Yohimbine, Dimethyl 4 and Hydroxy Phenylethylamine.
related amino acids are the dominant form of excitatory neurotransmitter in the central nervous system of
this drug as a "schedule I" drug that means that it has high potential for abuse.
Pseudoephedrine (PSE) is found in common cold, non-prescription medications. This ingredient has been used as part of the process for making methamphetamine (meth). PSE was easily obtained until a law was passed to control how obtainable it is. Although this law has caused PSE to be harder to obtain, it does not make it difficult to obtain resulting in meth still being created easily. There is a need to federally regulate the obtainability of PSE such as making it a prescription drug.
useful in the relief of mild to moderate pain. It is also used as a cough remedy
There are several stimulant medications that are commonly used throughout the world to treat behavioral disorders for attention deficit/hyperactivity disorder, or ADHD. Some of the medications used to treat this disorder are Adderall, Concerta, Focalin, Methylin, Ritalin, and Vyvanse. These are all stimulant drugs that help treat the symptoms of ADHD in very similar ways. I will specifically be focusing on Adderall. Adderall is constructed of amphetamine and dextroamphetamine which are central nervous system stimulants. Central nervous system stimulants affect the chemicals in the brain and nerves that contribute to hyperactivity and impulse control. Not only can Adderall be a life changing medication when prescribed to a patient with ADHD,
The first of these families, and the group about which most is known, is the amine neurotransmitters, a group of compounds containing a nitrogen molecule which is not part of a ring structure. Among the amine neurotransmitters are acetylcholine, norepinephrine, dopamine, and serotonin.
Did you know that pesticides have been used since the 1600s? Yes in the 1600s the romans burned sulfur to kill insects and they used salts to control weeds. The romans also used honey and arsenic to control ants. The ancient romans crushed the petals of the pyrethrum and they used ants to to eat undesirable insects. By World War II, only thirty pesticides existed(During the late 19th century, farmers were using copper acetoarsenite, calcium arsenate, nicotine sulfate, and sulfur to control insect pests in crops. Pesticides are products that are intended to prevent, destroy, repel, or to mitigate any pest. Pesticide use emerged after World War II, when DDT, BHC, Aldrin, dieldrin, endrin, and 2, 4-D was introduced. After these were introduced, people began abusing these pesticides and the pests became genetically resistant to pesticides. When this happened, non-target plants and animals were harmed and pesticide residues appeared in unexpected places. Researchers during the 1960s, began developing a different approach towards pest control. This was called integrated pest management (IPM). There are ups and downs to pesticides. When we didn’t have pesticides, there was bug spots on the produce,and blemishes. Most people won’t buy the produce if it has these kind of disorders. After pesticides were invented, we didn’t have these sort of problems, therefore sales went up.
The amino acid that is involved in this disorder is tyrosine. Tyrosine is one of the most insoluble amino acids4. It comes from two sources, diet and hydroxylation of phenylalanine. 4 The degradation of tyrosine is a catabolic pathway. Catabolic pathways are used to break down larger ...
Eighty-five percent of athlete teenagers are not educated on the use of enhancement drugs. Enhancement drugs have negative effects on the body, give unfair advantage to other athletes, and make the doper a bad role model for our future generation. As a result, Olympic athletes should get tested for enhancement drugs because they affect themselves and others negatively. This also sets a bad reputation for athletes who admits to doping.