University of Manchester is the utmost choice for my PhD study as it is the only institution in the world offering PhD in Biotechnology and Enterprise program which caters both comprehensive research training as well as entrepreneurship skills which are crucial in the industry but absent in other top universities. Manchester is also a member of the Russell Group, representing UK top universities which are committed to maintaining the very best research, an outstanding teaching and learning experience also unmatched links with business and the public sector. Thus, it is authorised that Manchester is one of the top university in terms of research quality and learning experience. Furthermore, I am impressed with the international reputation Manchester has maintained as top 10 UK-ranked universities in Life Sciences for the past decades besides offering numerous impressive research projects in biotechnology field and acquiring finest research facilities. I believe Manchester’s prestige, high standards and best quality are worldwide famous as the skills thought are extremely relevant and much appreciated by both employers and the industries.
Previously, I have carried out a research project entitled “Functional Characterisation of non-protein-coding RNA in Escherichia coli” where the exposure and experience I obtained from this project has developed my strong interest in the molecular biology field, particularly in the gene expression studies. Hence, I decided to continue my PhD research in the similar field but rather focusing in the applications aspect of biotechnology. As I have always wanted to pursue my career towards the industrial biotechnology sector, I was eager to carry out a research that comprises both aspects of gene stud...
... middle of paper ...
...eering the microorganisms, it is possible to create biofuel lipids with minimal or no feedstock necessary, just sunlight and CO2, much like plant photosynthesis.
In addition to the above points, Malaysian government also has been vigorously promoting and funding researches in local higher learning institutions for the past decades. Even though they are conducting remarkable researches to date, however it is a fact that the society are not directly benefiting from the findings as we are lacking in commercialising the findings into useful products Thus, I trust with the scientific and entrepreneurship background I will be attaining from the program, I would be able to initiate the commercialisation of the various scientific findings in Malaysia and the best way to start is through biofuel commercialisation among many other biotechnology and biopharmaceutical products.
Modern biotechnology was born at the hands of American scientists Herb Boyer and Stain Cohen, when they developed “recombinant deoxyribonucleotide, (rDNA), [1] for medicinal purposes. Subsequently, biotechnologists started genetically engineering agricultural plants using this technology. A single gene responsible for a certain trait, from one organism (usually a bacterium) is selected altered and then ‘spliced” into the DNA of a plant to create an agricultural crop consisting of that...
There is a lot of talk about the world’s source of energy going on these days and people are starting to ask questions about our sources of energy. Is it environmentally friendly? Does it make sense economically? For years the world has been highly dependent on fossil fuels that are extracted from the ground. These fuels power things from power plants, cars, plains, and many of the other modern conveniences that we enjoy. There is a lot of energy expended in the extraction and transport of these fuels as well as many negative environmental impacts. Scientists are busy finding alternative ways to power our world that are cost efficient and ecofriendly. One idea that is being explored as an effective replacement is producing oil from algae. Algae have a high content of oil, about 50 percent of its weight, and science is finding a way to use it as a clean fuel source.
There are a lot of reasons why I chose to pursue pharmacy as my career and they all point to the most important reason: pharmacy is a great fit for my life and is something I have become increasingly passionate about. It started when I was researching careers with my parents and my dad suggested pharmacy and, simply put, it sparked my interest because at the time it was one of the few things I thought I would not hate doing. A healthcare career has always been where I put myself in the future, mainly because most of my family members are in the healthcare field. However, I have never been one that could directly help the wounded or deal with anything gory, but am very intrigued by the growing science of pharmacy. As I continue exploring pharmacy, the more I enjoy learning about it and feel like I could excel in this career.
Gene expression is the ability of a gene to produce a biologically active protein. This process is regulated by the cells of an organism, it is very important to the survival of organisms at all levels. This is much more complex in eukaryotes than in prokaryotes. A major difference is the presence in eukaryotes of a nuclear membrane, which prevents the simultaneous transcription and translation that occurs in prokaryotes. Initiation of protein transcription is started by RNA polymerase. The activity of RNA polymerase is regulated by interaction with regulatory proteins; these proteins can act both positively, as activators, and negatively as repressors. An example of gene regulation in cells is the activity of the trp operon. The trp operon encodes the genes for the synthesis of tryptophan. This type of gene, like the lac operon, is regulated by a repressor that binds to the operator sequences. The activity of the trp repressor is enhanced when it binds tryptophan; in this capacity, tryptophan is known as a corepressor. Since the activity of the trp repressor is enhanced in the presence of tryptophan, the rate of expression of the trp operon is graded in response to the level of tryptophan in the cell. Another example of gene regulation in cells is gene amplification. This is a Technique by which selected DNA from a single cell can be duplicated indefinitely until there is a sufficient amount to analyse by conventional genetic techniques.
Please discuss the following items in the order given. Briefly respond to all areas listed.
The increased use of nonrenewable fossil fossil fuels which are nonrenewable and awareness about environmental changes has been led to the development of fossil fuel alternatives such as biofuels which is , a renewable resource. From In the past few years, the researchers have been applied various methods and examined various feedstock biomass feedstock’s such as corn, sugar cane, canola, soybean and lignocellulosic crops for the production of biofuels. The primary drawback of these first and second generation biofuels are the high usage of agricultural land. which This can lead to the a food crisis, high water usage, and high production time. The An alternative solution to the current situation is is the production of biofuels from microalgae. Microalgae are single single-celled organisms that grow in a wide range of aquatic environments , from fresh water through saturated saline and have the higher lipid content compared to what?. MicroaAlgae have the capacity to produce and accumulate energy-rich oils, have natural ability to accumulate oil in its dry biomass. The genetic diversi...
I believe that my attending SIMR will be one of the most important stepping-stones for me to achieve my goals in the field of medicine. While I do have the basic lab knowledge one would need to attend SIMR, The knowledge I will gain by being mentored by world-class scientists will set me apart and imbue me with the skills I need to succeed in my chose career in the biomedical field. Honing both the creative and analytical skills, learning the proper methods of experimentation and investigation, and experiencing the unique atmosphere of being among the future pioneers of the medical field are all things that will define my career in the field I have been infatuated with for years. Following my introduction to biotechnology, I was enamored by
For a number of years now the United States has been the mainstay in the push for biotechnology research and testing...
Distinct characteristics are not only an end result of the DNA sequence but also of the cell’s internal system of expression orchestrated by different proteins and RNAs present at a given time. DNA encodes for many possible characteristics, but different types of RNA aided by specialized proteins sometimes with external signals express the needed genes. Control of gene expression is of vital importance for an eukaryote’s survival such as the ability of switching genes on/off in accordance with the changes in the environment (Campbell and Reece, 2008). Of a cell’s entire genome, only 15% will be expressed, and in multicellular organisms the genes active will vary according to their specialization. (Fletcher, Ivor & Winter, 2007).
To excel in the field of Biology is not merely my dream, but my passion. I have started on this path of never-ending discovery and I want to master this science. It would not be unjustifying to state that the world is a better place today because of the advances in biological sciences. It truly promises to be an ever-advancing profession on this planet where better cures are required for freshly determined diseases on a day-to-day basis. Gene Technology and Biotechnology are a boon to this world. Putting microorganisms to use in the formation of insu...
Energy, especially from fossil fuels, is a key ingredient for all sectors of a modern economy and plays a fundamental role in improving the quality of life in less developed economies. In 2007, India is ranked fifth in the world in terms of energy demand; accounting for 3.6% of total energy consumed, and is expected to grow at 4.8% in the future. India imports 70% of the oil it uses, and the country has been hit hard by the increasing price of oil, uncertainty and environmental hazards that are concerned with the consumption of fossil fuels. In such context, bio energy constitutes a suitable alternative source of energy for India, as large amounts of raw material are available to be harnessed.
Microalgal biotechnology has emerged due to the great diversity of products that can be developed from biomass. Microalgal are photosynthetic prokaryotic or eukaryotic microorganisms that grow rapidly and have the ability to live in different environment due to their unicellular or simple multicellular structure.Microalgal have a simple cellular division cycle which allows them to complete their development cycle in a few hours. Microalgal when subjected to physical and chemical stress can produce high concentration of certain compounds for example proteins, lipids, carbohydrates, polymers and pigments.To produce these products, microalgae are grown using carbon dioxide,sunlight and industrial wastes in open pond systems and photobioreactors . Usage of industrial wastes reduces cost of culture medium nutrients and also reduces environmental problems.The fuel that we obtain now are mostly from fossil fuels and they are not a renewable source of fuel. Thus it is important that we find another alternative source of fuel. The growth of Algae Oil is a recognised process due to its final products and the production of oil is a function of the selection and feeding of a specific strain of algae. The production of Algae Oil is primarily used in the process of producing biodiesel fuel. All Biofuels are made from biomass. These biofuels can all be produced from algae. Microalgae contains oil within its cell. This oil can be used to make biodiesel. There are many kinds of microalgae which contains oil. Once they are grown, the oil is removed from the microalgae using chemicals or by squeezing oil out of the cells using scientific equipment.The oil is used as an ingredient in biodiesel. This oil is changed chemically from plant o...
For the biotechnology industry, the future is now. Biotech companies are producing new and improved drugs, mapping the genome, and creating artificial organs and body parts. The advent of these new products will increase the quality of life for those who have access to them. Advancements in the biotechnology field have received a lot attention by the press and publications. They have given the impression that it is almost imperative to learn about this fairly new field of study.
After basic education, I have developed a strong urge to attain academic excellence and to engage in research in the field of virology. I strongly feel that an MS from a reputed university will help me achieve my goal. United States will offer me a very conducive atmosphere for research and development.t I am eagerly awaiting for admission from your esteemed university and embark for my future journey in this field.
Biofuels can be produced either by First Generation of Biofuel (FGB), Second Generation of Biofuel (SGB), Third Generation of Biofuel (TGB) or Fourth Generation of Biofuel. FGB is mainly derived from food crops where it had created an issue regarding on competition of food for...