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Dementia introduction paper
Alzheimer diseases abstract esaasy
Dementia introduction paper
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Alzheimer’s disease is a type of dementia that affects cognitive function in the elderly population. The exact cause of the disease is unknown but may include genetic as well as environmental factors. A progression of specific neurological changes allows the progression of the disease. Short-term memory losses along with dementia are typical symptoms of the disease. A definite diagnosis of the disease currently can only be confirmed by an autopsy. The disease progresses in five stages that will vary with every patient. There is no current acceptable treatment to reverse or stop the progression of the disease.
Pathophysiology, Progression, and Treatment of Alzheimer’s Disease
Alzheimer’s disease is a type of dementia that affects cognitive function in the elderly population. It is an irreversible, progressive disease involving decline in memory and other intellectual abilities (Spremo-Potparevic, Živkovic, Plecas-Solarovic & Bajic, 2011). According to the National Institute of Health, the majority of people who have Alzheimer’s are age 65 and older (NIH, 2012). Around two-thirds of Americans who have Alzheimer’s are women. The reason for this may be that women have a longer lifespan than men (NIH, 2012).
A small percentage of those with the disease have early-onset Alzheimer’s. Of those who have early-onset Alzheimer’s an even smaller percentage have early-onset familial Alzheimer’s, which is the development of Alzheimer’s before the age of 65 along with the existence of a close relative who has the disease. This type of Alzheimer’s usually affects people in their 40’s or 50’s and is very rare (Huether & McCance, 2012). The third and most common type of Alzheimer’s is late-onset Alzheimer’s disease. Late-onset Alzheimer’s dise...
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Spremo-Potparevic, B., Živkovic, L., Plecas-Solarovic, B., & Bajic, V. P. (2011). Chromosome instability in alzheimer’s disease. Archives of Biological Sciences, 63(3), 603-608. doi:
10.2298/ABS1103603P
References
Huether, S., & McCance, K. (2012). Understanding pathophysiology. (5th ed., pp. 357-361). St.
Louis, MO: Elsevier.
NIH. U.S Department of Health and Human Services, National Institute on Aging. (2012). 2011-
2012 alzheimer's disease progress report. Retrieved from website: http://www.nia.nih.gov/alzheimers/publication/2011-2012-alzheimers-disease-progress-report/understanding-biology-alzheimers Spremo-Potparevic, B., Živkovic, L., Plecas-Solarovic, B., & Bajic, V. P. (2011). Chromosome instability in alzheimer’s disease. Archives of Biological Sciences, 63(3), 603-608. doi:
10.2298/ABS1103603P
Alzheimer’s disease was first defined in 1906 by a German psychiatrist, Alois Alzheimer. Alzheimer's disease is the most common form of dementia. It is a progressive brain disorder in which the nerve cells in the brain gradually die off. It is estimated that 26 million people world-wide are afflicted by Alzheimer’s and of those, approximately 4.5 million live in the United States. It is said to be the seventh leading cause of death in the USA and the fifth leading cause of death for those over age 65. Seventeen percent of women and ten percent of men age 55 and older can expect to develop Alzheimer’s (apa.org, 2009). Researchers report that this disease is more prevalent in African Americans and Hispanics than in whites (Crandell, Crandell, and Zanden, 2009, p. 578).
Thesis/Preview Statement – Alzheimer’s disease (AD) causes a decline in brain function, it destroys healthy nerve cells. Today, we have discussed Causes, Symptoms, and Diagnosis of AD.
Memory plays a significant role in the everyday lives of people of all ages. It allows them to recall information and remember skills that were learned in the past. Memory also organizes past information to help people make current and future decisions. However, imagine forgetting the names of close family members or not having the ability to find your keys every time you want to leave the house. These are some of the struggles that people with Alzheimer’s disease face daily. Alzheimer’s disease was first identified by German neurologist Alois Alzheimer in 1906, and was discovered to have an overpowering effect on explicit memory loss (Gruetzner, 1988). There are two types of Alzheimer’s disease – early onset and late onset. Early onset occurs in patients who are diagnosed before the age of 65 whereas late onset occurs in patients who are diagnosed after the age of 65. In the early stages of Alzheimer’s disease, short-term memory is often lost. As Alzheimer’s disease progresses, problems with long-term memory begin to develop, in addition to short-term memory impairments. Although a lot is known about the symptoms of Alzheimer’s disease, the cause has not been conclusively identified. However, as research continues, new theories about the cause of Alzheimer’s disease are being proposed. This has led to a controversy over whether Alzheimer’s disease is caused by genetics or environmental influences (Gruetzner, 1988).
Alzheimer’s can be diagnosed before age 65, although rare, and is caused by a mutation in 3 known genes. About 5 percent of those who are under 65 and possess the ailment have AD in their family history. Given that the symptoms of AD are caused by plaque in the brain, causing loss of nerve cells that help the body communicate with the brain, mutations to these genes; amyloid precursor protein, presenilin 1, and presenilin 2 cause a excessive production of certain proteins (primarily a B-42 form of amyloid protein), and therefore spark an excessive growth of plaque cells which are toxic to the neurons of the brain. For those cases of Alzheimer’s that occur after age 65, a genetic mutation has yet to be proven, although some may be linked, to the fact that a difference may cause an increased chance of developing the ailment. Whatever the case may be for patients over 65 years old, the disease and its symptoms are caused by neurofibrillary tangles of almyloid plaques. It is impossible for someone to test positive for Alzheimer’s Disease, because the only way to determine an affirmative case i...
Alzheimer’s disease is a complex illness that affects the brain tissue directly and undergoes gradual memory and behavioral changes which makes it difficult to diagnose. It is known to be the most common form of dementia and is irreversible. Over four million older Americans have Alzheimer’s, and that number is expected to triple in the next twenty years as more people live into their eighties and nineties. (Johnson, 1989). There is still no cure for Alzheimer’s but throughout the past few years a lot of progress has been made.
Alzheimer’s is a horrible disease that takes the lives of many. There is someone diagnosed with Alzheimer’s around the world every seventy-two seconds. It is a form of dementia that slowly takes away the most basic of memories all the way to the memories of children, weddings, and even the saddest ones such as family death. The people that Alzheimer’s affects have a hard time with remembering tiny details and the disease begins with taking away the function of short term memory. This happens because the levels of acetylcholine are known to drop up to ninety percent beginning in the entorhinal cortex and moving into the hippocampus. Because of this, of the first signs of Alzheimer’s is the loss or decrease of the sense of smell, hence the entorhinal. The cells in the hippocampus called the hippocampal cells lose their connection and the result of this is the total loss of short-term memory. The neurons resting in the cerebral cortex then start to degenerate which in turn leads to the difficulty with the function of language and judgment. This also causes appetite to decline and then there is the loss of control over bowel movements. The disease will progress with many ending up not even recognizing their own children, much less being able to eat or bath or do simple tasks that they normally would not even have to think about.
Alzheimer’s is a disease that many people have heard of, but few really know much about. Imagine not being able to remember your loved ones and friends or even how to do simple tasks like dressing yourself and brushing your hair. Now imagine having to dress your mother, who rarely remembers you anymore. This is the reality of life for millions of older people afflicted with Alzheimer’s disease and the families that care for them. Alzheimer’s causes cognitive function to decrease gradually overtime. Alzheimer’s disease is the most common form of dementia - affecting around 5 million Americans (alz.org). It is the most fatal disease affecting older people and needs to be taken seriously.
Cummings, Jeffrey L., Cole, Greg. “Alzheimer Disease.” Journal of the American Medical Association. May 2002: 287-18. Health Source. EBSCOhost. Utica College Lib. 15 Apr 2005. .
tends to increase with age, but there is a big difference between normal forgetfulness and Alzheimer's disease. There are three things to know about Alzheimer's: the facts and figures, the seven stages, and the changes in the brain.
In the modern age scientists and researchers are constantly discovering new diseases and disorders that affect the human body. With technology improving and new equipment being introduced it enables scientists to gain more knowledge about the disorders than ever before. During the last century a German physician by the name of Alois Alzheimer linked a patient’s memory loss to her brain autopsy which displayed signs of brain shrinkage. His discovery is now known today as Alzheimer’s disease; which is a form of dementia and is a psychological disease that causes the brain to deteriorate. In today’s day and age, there are still many unanswered questions about Alzheimer’s disease (Crider, A., Goethals, G., Kavanough, R., & Solomon, P. 1989). A few known facts are that Alzheimer’s disease is it is most commonly found in elderly humans, with majority of carriers being age 60 or older. It is important to note that Alzheimer’s disease is not an old person’s disease and that it can also be found in adults of younger ages. Furthermore, there are two forms of Alzheimer’s disease. The two forms are called Early-onset which is found in adults ages 30-59 and Late-Onset which is more common and occurs in adults ages 60 and up. Alzheimer’s disease may not be curable, however with the right information it can be easy to conquer (Alzheimer and Dementia Resources).
People that are diagnosed with Dementia have an advanced brain disorder that can make it progressively more difficult for them to think clearly, remember things, communicate to others, or even take care of themselves on their own. I have been personally affected by this disorder through members of my family and that is why this particular lecture caught my attention the most. I didn’t realize how serious this disorder can be and how much it not only impacts a person’s memory loss, but many other aspects of their life. The topics that interested me the most and ones I wanted to learn more about were normal aging memory loss versus symptoms of Dementia, how families cope with a loved one with Dementia, and the difference between Dementia and Alzheimer’s disease.
Alzheimer's disease is the most common form of dementia, and this terminal, progressive brain disorder has no known cause or cure. Its greatest known risk factor is increasing age which is why is it is infamous for developing in the elderly, typically in ages 65 or over, however for the 5%(1) that develop Alzheimer’s in their 40s or 50s it is known as early Alzheimer’s. Because Alzheimer’s worsens over time, those with it tend to struggle with completing daily tasks especially elderly people. Given that there is no cure for Alzheimer’s, the treatments available slow the worsening of dementia symptoms and improve quality of life for those with Alzheimer’s and their caregivers. It is not known what causes Alzheimer's, however, those with Alzheimer's have been found to have abnormal amounts of protein (amyloid plaques) and fibres.(The amyloid plaques and fibres are found in regions of the brain where problem solving and thinking take place e.g The cerebrum.) Due to the unusual amounts of amyloid plaques and fibres, it reduces the effectiveness of healthy neurons and eventually, destroying them.
It is said that memory declines as people age, and this can be just a natural part of life. However, in many cases as people grow older, they develop a mental disorder known as Alzheimer’s disease. Alzheimer’s is a disease that causes problems with memory, thinking, and overall behavior, and progressively becomes a bigger problem. Alzheimer’s is the most common form of dementia and is a very common disease in people over the age of 65. This terminal disease puts tremendous stress on the victim and the victim’s family. A cure for Alzheimer’s has yet to be discovered; however, through healthy and constant use of the brain and the aid of certain drug treatments, Alzheimer’s disease can be both naturally and medically prevented.
Alzheimer disease generally occurs in people over seventy five years of age; however it does strike people in their forties, fifties, and sixties, but this is rare. When Alzheimer’s disease occurs prior to the age of sixty five, it is referred to as early onset Alzheimer’s.
This usually occurs in older adults aged above 65; however, it is a disability and not a normal symptom of aging. Chances of inheritability are present, but it depends on the individual and the type of dementia (Alzheimer Australia, 2011). The Global Deterioration Scale provides a detailed explanation of the seven stages of cognitive decline in dementia (Alzheimer’s Association of Canada, 2005). Types of Dementia There are four main types of dementia, with AD being the most widespread form. It accounts for almost two thirds (50 -70 percent) of the cases and thus more extensively studied (Miller, 2009)....