OxyContin
Painkillers have been used for many years, and they have been beneficial to many. But one that recently took the market has been the topic of many controversial discussions. Oxycodone has always been used in modern medicine but in small amounts. OxyContin contained a higher amount of oxycodone than most opiate based pain killers, the weakest dose of OxyContin had double the amount found in said painkillers (Meier 12). This lead to the spread of abuse and addiction towards the drug. And a medicine made to do nothing but help became the subject of overdose and death. The creation of OxyContin was a triumph for modern medicine and a halo of light to people with chronic pains, but this drug now seems to carry a trail of addiction and abuse along with it.
Granted, opioid based Pain killers like OxyContin have been invented and used for centuries. It was Hippocrates who first used opioids as a form of medicine. He used opium to stop the pain of internal illnesses, like "women’s diseases" (Blachford and Krapp). But as time went on chemists were able to actually separate and isolate more compounds from the opium plant, such as the chemical Thebaine, the main substance used to make Oxycodone (Meier 57). Oxycodone is the chemical in OxyContin that gives it the pain killing effects, it was developed in Germany circa 1916, and they labeled it under the name Eukodal (Blachford and Krapp). From there, the FDA first approved the use of Oxycodone in 1976 (Blachford and Krapp). Then In 1996 a drug manufacturer by the name of Purdue Frederick started the sale of Oxycodone under the brand name OxyContin, in order to sell the drug he opened a special unit known as Purdue Pharma (Meier 12). Following the release in 1996, it became highly sou...
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... less, OxyContin’s intended purpose was to do nothing but help people stop suffering from pain. It’s able to fix many people pains and it was favored because it is derived from opium. The only issue is that it’s more addictive and side effect driven than anyone could have imagined. However, it was not an innovation in the way people thought it would be. The drug caused many different side effects and addiction related overdoses. In all honesty and in my opinion, I think that the chemical Oxycodone is safe in small doses, but if this pain killer is OxyContin than nothing but trouble will surely ensue. The drug was made for good, but the bad has outweighed this by a million to one. The creation of OxyContin was a triumph for modern medicine and a halo of light to people with chronic pains, but this drug now seems to carry a trail of addiction and abuse along with it
Before the mid 1900’s the Harrison Narcotics Tax Act was formed to tax those making, importing or selling any derivative of opium or coca leaves. In the 1920s, doctors became aware of the highly addictive nature of opioids and started to avoid treating patients with them (Center, 2004). In 1924 heroin became illegal. However according to a history published in the Journal of the American Medical Association in 2003, anesthesiologists opened "nerve block clinics" in the 1950s and 1960s to manage pain without having to resort to surgery (Meldrum, 2003). This push for treating pain without surgery was a major factor in the opioid epidemic we see today. In 2008 the overdose death rate was almost four times the rate in 1999, and the sales of prescription pain relievers in 2010 were four times higher than in 1999 (Paulozzi et al, 2011). The substance use disorder treatment admission rate is also greater than in 1999, with it having been six times higher in 2009. Chasing Heroin’s claims surrounding the fear of prescribing pain medications is accurate as you see an increase in public policies surrounding opiate use in the early 1900’s. The climbing rates of overdose deaths and the increased amount of people seeking addiction treatment suggests that the fear of prescription opiates was
Almost one hundred years ago, prescription drugs like morphine were available at almost any general store. Women carried bottles of very addictive potent opiate based pain killers in their purse. Many individuals like Edgar Allen Poe died from such addictions. Since that time through various federal, state and local laws, drugs like morphine are now prescription drugs; however, this has not stopped the addiction to opiate based pain killers. Today’s society combats an ever increasing number of very deadly addictive drugs from designer drugs to narcotics to the less potent but equally destructive alcohol and marijuana. With all of these new and old drugs going in and out of vogue with addicts, it appears that the increase of misuse and abuse is founded greater in the prescription opiate based painkillers.
Where did this drug come from and what makes it different from any other drug that is on the market? Heroin's origins go back long before Christ was a bleep on the radar. It goes back to 1200 B.C. Or the Bronze Age. At that time how ever heroin would be known as its chemically altered state of the poppy seeds. Even at that time however the ancient peoples of that time knew that if the poppy seeds juice were collected and dried. the extract that was left behind could make a effective painkiller. This would later be named opium. There were small incidents of it appearing in Europe, for instance it was used by the gladiators in the Roman Colosseum. But as a whole it would take more then a millennium for opium to travel from the Middle East to the Europe. This only occurred do to crusades. In just a few hundred after that is went from a rarely used painkiller to a liquid that was said to cure all aliments and would even lead to the most humiliating defeat China Empire. In the 1803 opium became dwarfed by its new brother morphine which is named in honor of the Greek god Morpheus who is the god of dreams. Morphine is an extract of opium and is ruffly 10 times the strength of its counter part. After Morphine creation it was put to used almost at once to assist battle field victims. This was a mistake however, because this refined does of opium is also 10 times more addicting then it was in its original form. Hundreds of thousands of soldiers would retur...
Opioid addiction is a tragedy that affects countless of Americans on a daily basis. Almost everyone is acquainted to someone, who suffers from opioid addiction. Everyone, but specifically family and friends of the victims to opioid addiction need to understand why their loved ones are so susceptible to becoming addicted to opioids. The word opioid in itself is complex to define, but it entails a variety of prescription medications. Most opioids are used as pain management medications and qualify as CII medications also known as narcotics. They are supposed to be used on an “as needed” basis, but that is not the case for many users of opioids. Opioids cause great fear in the health community because they are easily addictive and
By the year 2000 opioid medicine containing oxycodone etc., are being abused and misused and more than doubled in 10 years’ time.
Opioid’s chemical composition consist of many highly addictive substances which cause the human body to become quickly tolerant. Many opioid users become addictive to the substance because the doctors have been over prescribing. “In the United States, there were 14,800 annual prescribed opioid (PO) deaths in 2008” with the US having less restrictions (Fischer, Benedikt, et al 178). The United States have implemented more regulations so that “high levels of PO-related harms been associated with highly potent oxycodone formulas” will decrease (Fischer, Benedikt, et al 178). With the regulations, it does not change the fact that opioids are is destructive. The regulations assistance by lessening the probability of patients becoming addictive to opioid. There are numerous generations that are effected and harmed by the detrimental effects of opioids on opioid-dependent patients.
According to CDC in the year 2015 opioids played a part in 33,091 deaths. Now you may ask what an opioid is. An Opioid is a compound that binds to opioid receptors in the body to reduce the amount of pain. There are four main categories of opioids, one being natural opioid analgesics including morphine and codeine, and semi synthetic opioid analgesics, including oxycodone, hydrocodone, hydromorphone, and oxymorphone. The second category being methadone, a synthetic opioid, the third category being synthetic opioid analgesics other than methadone includes tramadol and fentanyl. The last category is an illicit opioid that is synthesized from morphine called heroin.
There are different forms of Opioids manufactured such as Morphine, Oxycodone, Buprenorphine, Hydrocodone, and Methadone. They are marketed under different brands such as Demerol, Oxycontin, Tylox, Percocet, and Vicodin and can be prescribed in liquid, tablets, capsules, and patches.
In medical school/pharmacology school, medical professionals are taught to treat severe pain with opioids. However, opioids should be prescribed with the possibility of future dependency in mind. Physicians often struggle with whether they should prescribe opioids or seek alternative methodologies. This ethical impasse has led may medical professionals to prescribe opioids out of sympathy, without regard for the possibility of addiction (Clarke). As previously stated, a way to address this is use alternative methods so that physicians will become more acquainted to not not treating pain by means of opioid
Acid is produced naturally in your stomach to help you digest food and to kill bacteria. This acid irritates the stomach lining so our body produces a natural mucus barrier which protects it. Sometimes this barrier may be damaged thus allowing the acid to damage the stomach causing inflammation, ulcers and other conditions. Other times, there may be a problem with the muscular band at the top of the stomach that keeps the stomach tightly closed and this allows the acid to escape and irritate the oesophagus. This is called 'acid reflux' and can cause heartburn and/or oesophagitis. Proton pump inhibitors such as omeprazole stop cells in the lining of the stomach from producing too much acid. This can help prevent ulcers from forming or assist the healing process. By decreasing the amount of acid, they can also help to reduce acid reflux related symptoms such as heartburn.
Cocaine Take Over Cocaine is the second most popular illegal substance in the United States and continues to be, no matter how severe the damage to people can be. People let drugs take over them, cocaine ruins them not only mentally but also physically. They let this drug ruin their lives only for temporary pleasure, and don't realize how much it can hurt them in the long run. Those who do realize how it hurts their future, still let this illegal substance control their lives. Cocaine is a drug extracted from the leaves of a coca plant and is one of the most used and addictive drugs.
Opium, the first opioid, is derived from the sap of opium poppies, whose growth and cultivation dates back to the ancient civilization of Mesopotamia around 3400 BC. Egyptians and Persians initially used opium. Eventually spreading to various parts of Europe, India, China, and the Middle East. During the 18th century, physicians in the U.S. used opium as a therapeutic agent for multiple purposes, including relieving pain in cancer, spasms from tetanus, and pain attendant to menstruation and childbirth. It was merely towards the end of the 18th century that some physicians came to recognize the addictive quality of opium.
The rate of death due to prescription drug abuse in the U.S. has escalated 313 percent over the past decade. According to the Congressional Quarterly Transcription’s article "Rep. Joe Pitt Holds a Hearing on Prescription Drug Abuse," opioid prescription drugs were involved in 16,650 overdose-caused deaths in 2010, accounting for more deaths than from overdoses of heroin and cocaine. Prescribed drugs or painkillers sometimes "condemn a patient to lifelong addiction," according to Dr. Tom Frieden, director of the U.S. Centers for Disease Control and Prevention. This problem not only affects the lives of those who overdose but it affects the communities as well due to the convenience of being able to find these items in drug stores and such. Not to mention the fact that the doctors who prescribe these opioids often tend to misuse them as well. Abusing these prescribed drugs can “destroy dreams and abort great destinies," and end the possibility of the abuser to have a positive impact in the community.
"OxyContin: The History of OxyContin." Drug Rehab, Alcohol Addiction Treatment and Detox | Michael's House. Web. 22 June 2010. .
Although oxycodone relieves pain, it is an addictive drug that causes major harm to the brain, and body and affects individuals life’s as well as the economy. The problems that this drug causes outweighs its benefits. I believe this drug should be banned from the medicine market due to the damages it has caused over the years. Oxycodone is a prescribed legal drug used to relieve moderate to severe pain following surgery and can also be used to treat pain in cancer patients (“Oxycodone”). Oxycodone is a semisynthetic opioid; it is obtained from thebaine an alkaloid found in opium and it is created in laboratories (“Oxycodone”).