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Mabthera multiple sclerosis
Mabthera multiple sclerosis
Mabthera multiple sclerosis
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Introduction
Multiple Sclerosis (MS) is a debilitating autoimmune disease. The Central Nervous System (CNS) is attacked by the immune system; creating lesions that interrupt the correct signaling of nerves, spinal cord, and brain (Frankel, & James, 2011). Inhibiting development of this disease is crucial for maintaining quality of life and fatigue for individuals with MS. There has been vast amount of research on the effect of various exercise training programs, and their benefits for MS (Motl, & Gosney, 2008, Krupp, 2003, Chen, Fan, Hu, Yang, & Li, 2013). Balance, aerobic, and strength training have been the main focus of most researchers; causing an interest in what training mode is most effective for improving quality of life and lower fatigue. It is critical to examine and contrast the effectiveness of a variety of exercise programs, because if training is completed effectively it can drastically improve quality of life and fatigue for individuals with MS.
Developing a greater understanding of the effect of exercise on individuals with MS requires attention to two specific gaps. First, there is limited knowledge on what type of exercise (balance, aerobic or strength training) is most effective. Because exercise is beneficial to improve fatigue and quality of life, it is vital to examine which mode of exercise offers the best results (Motl, 2008). Second, there is limited knowledge on the effectiveness of exercise programs that can be completed at a non-clinical setting (i.e. community or recreation center). It is important to examine non-clinical settings because of realistic application for MS patients.
To address these gaps, focusing on exercise mode and setting is critical. MS patients struggle with fatigue, making it di...
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...gait in persons with multiple sclerosis. Advances in Physiotherapy, 9(3), 136-143.
Pantea, C., Sîrbu, E., & Pantea, S. (2011). Effects of physical activity on functional and cardio respiratory capacity in multiple sclerosis. Timisoara Physical Education & Rehabilitation, 4(7), 29-35.
Pilutti, L. A., Lelli, D. A., Paulseth, J. E., Crome, M., Jiang, S., Rathbone, M. P., & Hicks, A. L. (2011). Effects of 12 weeks of supported treadmill training on functional ability and quality of life in progressive multiple sclerosis: a pilot Study. Archives of Physical Medicine & Rehabilitation, 92(1), 31-36.
Tarakci, E., Yeldan, I., Huseyinsinoglu, B. E., Zenginler, Y., & Eraksoy, M. (2013). Group exercise training for balance, functional status, spasticity, fatigue and quality of life in multiple sclerosis: a randomized controlled trial. Clinical Rehabilitation, 27(9), 813-823.
However, I am not going to spend a long time describing the nitty-gritty of this because there is an elephant in the room. Both of these writings are on a terrible chronic disease affecting millions of people worldwide. What’s worse is that millions and millions more do not even know that this disease exists. I remember when I sprained my ankle while playing baseball, it was so bad that I needed crutches for two weeks and had to keep my foot wrapped for multiple weeks after. The incident took me out for the rest of the season, where my little league team got very close to going into the postseason but fell short. Due to my absence, I felt partly responsible for my team’s loss. I cannot begin to fathom the effect that MS would have in my life
Rietberg MB, Brooks D, Uitdehaag BMJ, Kwakkel G. Exercise therapy for multiple sclerosis (Review). Cochrane Database Syst Rev. 2004;3.
Fatigue, decreased mobility and impaired balance from the rheumatoid and osteoarthritis pain also increases the risk of falls (Stanmore et al., 2013). Age related changes such as sarcopenia causes muscle tone and strength to decrease, especially in the lower limbs and as a result, balance and gait become impaired (Culross, 2008). These factors significantly influence the risk of falls and also affect the ability to carry out daily activities therefore, with a physiotherapists assistance, the nurse could introduce a personalised exercise regime to enhance muscle tone and strength (Culross, 2008). According to Neuberger et al (1997), exercise lessens fatigue and improves muscle tone and balance in older people. Recommending an exercise programme for Mrs Jones that incorporates strength training exercises and aerobics, could potentially improve muscle tone and strength and as a result improve mobility, balance and lessen the risk of falls (Bird, Pittaway, Cuisick, Rattray & Ahuja, 2013). The nurse could also suggest safety precautions such as advising Mrs Jones to use a mobility aid (Gooberman-Hill & Ebrahim,
With MS, most people experience exacerbations, where symptoms get progressively worse, which are then “followed by periods of reduced or no symptoms,” indicative of remission (PubMed Health 2013). Though for many it is “common for the disease to return (relapse), […for some] the disease may continue to get worse without periods of remission” (PubMed Health 2013). Also, the severity of the disorder can be amplified by exposure to extreme heat in addit...
responses during prolonged treadmill walking with heavy load carriage. Medicine and Science in Sports and Exercise. 26:285-288.
According to National Multiple Sclerosis Society, Multiple Sclerosis (MS) is an unpredictable, often disabling disease of the central nervous system (CNS) that disrupts the flow of information within the brain, and between the brain and body. The central nervous system (CNS) comprises of the brain and the spinal cord. CNS is coated and protected by myelin sheath that is made of fatty tissues (Slomski, 2005). The inflammation and damage of the myelin sheath causing it to form a scar (sclerosis). This results in a number of physical and mental symptoms, including weakness, loss of coordination, and loss of speech and vision. The way the disease affect people is always different; some people experience only a single attack and recover quickly, while others condition degenerate over time (Wexler, 2013). Hence, the diagnosis of MS is mostly done by eliminating the symptoms of other diseases. Multiple sclerosis (MS) affects both men and women, but generally, it is more common in women more than men. The disease is most usually diagnosed between ages 20 and 40, however, it can occur at any age. Someone with a family history of the disease is more likely to suffer from it. Although MS is not
Valent, Linda J.M. Et al. "Effects of Hand Cycle Training on Physical Capacity in Individuals With Tetraplegia: A Clinical Trial." Physical Therapy 89.10 (2009): 1051-060. Print.
Wiley Online Library, 2013. The Epidemiology of Multiple Sclerosis [online] Available at: <. http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0404.1997.tb08143.x/abstract> [Accessed 05 December 2013].
Fibromyalgia is one of the most expensive chronic diseases in terms of healthcare utilization costs in part due to the severity of the functional limitations experienced by fibromyalgia patients. The clinical symptoms of fibromyalgia are complex and are accompanied by sleep disturbances, mood disorders, chronic fatigue, reduced exercise tolerance and pain exacerbations which severely limit a patient’s activities of daily living (Friedberg et al., 2012). As a result, fibromyalgia patients often adopt sedentary behaviors that reinforce preexisting physical disabilities and ultimately lead...
Due to the strong and growing evidence in scientific literature on the beneficial effects of physical activity on health and well-being, the importance of Clinical Exercise Science has increased. Physical activity is defined as any bodily movement produced by skeletal muscles that requires energy expenditure. Exercise, is a subcategory of physical activity that is planned, structured, repetitive, and purposeful in the sense that the improvement or maintenance of one or more components of physical fitness is the objective (http://www.who.int/dietphysicalactivity/pa/en/; last accessed on 30 April 2016). Generally speaking, Clinical Exercise Science is an applied clinical branch which deals with the application of various exercise modalities for
Patients are presented with Multiple Sclerosis in various different forms and experience symptoms to different degrees – mild, moderate or severe. While some patients’ predominately experience emotional or cognitive dysfunction, others may be presented with loss of muscle control, and/or visual, balance and sensation symptoms. Other symptoms include fatigue, bladder and bowel problems.
Multiple Sclerosis is a nervous system disease that affects the spinal cord and the brain by damaging the myelin sheaths that protects nerve cells. Destroyed myelin prevents messages from communicating and sending properly from the brain, through the spinal cord, to internal body parts. In the United States, more than 350,000 people are diagnosed with this disease. Anyone can get this disease, but it is more common among Caucasian women. MS symptoms begin between the ages 20-40 and are caused by nerve lesions being present in multiple areas of the Central Nervous System, symptoms differ on the lesion’s location.
This publication was printed with the generous support of the National Institute on Disability and Rehabilitation Research
Permuth-Levine. She brings up that practice isn't only vital for individuals who are as of now living with wellbeing conditions: "In the event that we can see advantages of moderate activity in individuals who are recuperating from sickness, we may see much more noteworthy advantages in those of us who are for the most part well."
The nervous system plays a major role in co-ordinating and controlling the body’s activities. It is made up of billions of nerve cells. These cells are linked to form a massive communications network. Nerve cells carry messages in the form of electrical impulses. These impulses are carried at high speed around the body to keep it safe and functioning normally. Multiple sclerosis (MS) is a disease which progressively injures the nerves of the brain and spinal cord. Injury to the nerves in multiple sclerosis may be reflected by alterations of virtually any sensory or motor (muscular) function in the body.