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History of the biomedical engineering career
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CHAPTER TWO
LITERATURE REVIEW
2.0. Historical Background Of Biomedical Engineering
The application of engineering principles and design concepts to medicine and biology is can be refer to as biomedical engineering also known as bioengineering. This combines the design and analysis of problem solving skills of engineering with medical and biological sciences with the aim of improving the quality and effectiveness of patient healthcare diagnosis, monitoring and therapy. Bioengineering applies engineering principles to the study of medical and biological problems. The goal of biomedical engineering is to use electrical, chemical and mechanical engineering principles to conduct studies and develop tools that can aid in the biomedical care of patients.
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It integrates physical, chemical or mathematical sciences and engineering principles for the study of biology, medicine, behavior or health. It advances fundamental concepts, creates knowledge from the molecular to the organ systems levels and develops innovative biologics, materials, implants, devices and informatics approaches for the prevention, diagnosis and treatment of disease, for patient rehabilitation and for improving health. Prominent biomedical engineering application include biocompatible prostheses, various diagnostic and therapeutic medical devices ranging from clinical equipment to micro-implants, common imaging equipment such as MRIs and EEGs, biotechnologies such as regenerative tissue growth, pharmaceutical drugs and biopharmaceuticals.
Biomedical engineering can trace its history to as far back as a hundred years ago when the first X-ray machines and electrocardiographs dramatically illustrated how technology could be used for the diagnosis of disease. Today the field of biomedical engineering is in full power, propelled by the momentum of the post-World war II technology boom and the latest molecular, genetic, and computational developments. Having gone beyond its roots in imaging and instrumentation, biomedical engineering now encompasses at least 13 specialties according to the 2000 edition of The Biomedical Engineering
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In 1891, J. Stoney suggested the name electron to the smallest particle of electricity.
The word electron was derived from the Greek word meaning ‘’amber’’. We can regard the electron as atom or particle of electricity and therefore electronic is defined as the study, control and application of flow of electrons in a vacuum.
Electronics can be divided into two branches: analogue and digital. Analogue electrics has developed through the ages of valves in the early 1900s, through transistors to integrated circuits in the 1960s. Analogue electronics deal with the processing of continuously varying signals. In analogue electronics, the amplitude of electrical signal, at any time is proportional to the magnitude of the information being processed. Digital signal consist of a pattern of pulses, usually of the same amplitude. Digital circuits make use of distinct voltage levels, a high level and a low level, to convey information and to control functions within the
The contributions of several doctors, researchers, and scientists helped improve the health of the growing population. In 1850 the average life expectancy was 42 years. By 1910 the average life expectancy had risen to nearly 55 years. Between 1850 and 1910 there were several advances in the medical field. The introduction of genes, white blood cells, blood groups, insulin, rubber gloves, aspirin, and vitamins and the discoveries of Pasteur, Charcot, Halsted, Zirm, Lister, and Koch were the starting point of an international fight against disease.
Engel, G. L. (1977). The need for a new medical model: a challenge for biomedicine. Science, 196(4286), 129–136.
These studies, in my opinion, hold to be necessary on my intended path to research breast cancer, and hopefully extend my investigations and findings to other types of cancerous diseases as well. Besides that, these degrees could not only be useful for research on cancer, but also in other types of disease research or development of modern technologies with the focus on sharpened imaging and detection, regenerative technologies, and biomechanics. That is why I also desire to apply my outstanding analytic and problem solving skills to extend my horizons. Therefore, I aim to earn a Bachelor of Science in Mechanical Engineer before completing graduate school or medical school, which would succor my future in research activities. Thus, I know that in order for to develop the latest technology additional fields of study remain necessary to create a cutting-edge and satisfactory solution to resolve a
With the kind of technology that is available to doctors and scientists, treatments and cures will begin to pop up as we continue to advance in technology. Genetic engineering is going to be the topic to look out for. With the incredible discoveries done from modifying genes, it has resulted to millions of lives saved. Vaccines had come a long way from the first discovery, inching towards the one hundred percent success rate. Fredrick made a ground breaking discovery with diabetes and provided a treatment and saved millions. Gene therapy began to prove itself in medicine as it reversed affects from a previously untreatable disease. Genetic engineering still has long ways to go, however it is a promising treatment that will bring us more treatment and cures in the future.
In the future, computing power will become greater and greater allowing for faster calculations and analysis of sequencing data. Also, there will be new robotics, micro-fabrication technologies and laboratory information management systems that will have to be applied to the challenges of the Human Genome Project (Bishop, 137). Furthermore, cutting edge researchers believe the really important discoveries won't come from looking at linear strands of genes but from examining the interaction between dozens of genes at once. Scientists could in theory use "biochips," arrays of hundreds of bits of your DNA placed in a silicon wafer, to examine how how a drug would interact with your particular biochemistry (Moore, 56).
Engel, G. L. (1977). A Need for a New Medical Model: A Challenge for Biomedicine. Science , 196, 129-136.
Genetic engineering has revolutionized over the years and it is being used to improve food, to discover new medicines, to remove environmental contaminants, to recycle waste, and to provide permanent cures for inherited diseases (Le Vine, 1999). The purpose of genetic engineering in the medical field has been to produce mass-produce insulin, human growth hormones, human albumin, monoclonal antibodies, vaccines, and many other drugs (Applications of Genetic Engineering,
The medical field has also reaped the benefits of genetic engineering. With the recent discoveries and understanding of so many debilitating diseases and injuries, researchers are working to develop new ways to keep humans healthier for longer amounts of time. Advances in technology, genetic engineering procedures, and new medicines have allowed researchers to discover methods that can be used to help those suffering from many diseases and injuries. According to an article entitled Genetic Engineering Breakthrough published in the News Medical, “Scientists have made extensive breakthroughs in muscle regeneration. They are attempting to help bed-ridden patients and elite athletes by engineering a ‘switch’ that will allow mutations or light signals to be turned on in muscle stem cells.” This discovery may also be used as a tool for the study of difficult-to-treat muscle cancers. Dr. Charles Keller, M.D., assistant professor at the University of Texas Health Science Center and a senior researcher involved in the work, stated that "We hope that the genetically-engineered mouse models we developed will help scientists and clinicians better understand how to make muscle stem cells regenerate muscle
There are different types of engineers in the world. There are the engineers that analyze the mechanics of a system that make it function, engineers that apply electricity to improve our daily lives, and then there are engineers who develop solutions to solve human health problems. The term bioengineering contains both the words biology and engineering, meaning that engineering concepts are applied to improve the lives of humans. Bioengineering is the future to improved health and living styles for human beings. I am fond to bioengineering because it improves the living of people who are in a body that cannot satisfy their daily needs of simply walking or moving at ease. I have a friend that is incapable to walk; therefore he will be sitting down in a wheelchair for the rest of his life unless bioengineering will help him finally get up to his feet for the first time of his life. It...
Great medical discoveries pertaining to genetic modification are being made regularly and scientists are discovering new ways in which genetic engineering could be used to update certain medical procedures in the future. Complicated procedures such as organ transplantation have been made more successful with the use of genetic modification. Lab-grown bladders, windpipes, blood vessels and skin are some examples of organic matter that have been successfully grown with human cells and transplanted into human patients. The demand that the human population has on donor organs far exceeds the number of organs available for transplant. Genetic modification is the solution to this problem, in that, the advances being made in therapeutic medicine will save millions of lives in the future. Now that it is possible to alter the genes of an organis...
Any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use to benefit the lives of humans or other organisms, in bettering their lives. (Essays, UK. (November 2013). Can Genetic Engineering Be Regarded As Biotechnology Biology?. April 2014, http://www.ukessays.com/essays/biology/can-genetic-engineering-be-regarded-as-biotechnology-biology-essay.php?cref=1)
When you look around, you see all kinds of modern wonders. None of these items would be possible without engineering. Engineering has shaped the lives of humans for thousands of years; it is simply the application of science and math to invent or innovate an item to carry out a human need. Recently, computer engineering has been the basis of the human world. We rely on computers like it is water or air, and it’s come to the point where they could be a necessity for success. Computers are used for pictures, data, development, research, design and much more. The mere fact that humanity prospered for so long without advanced computers is astonishing.
Science and Technology has been around from the beginning of time. It evolved from the everyday efforts of people trying to improve their way of life. Throughout history, humankind has developed and utilized tools, machines, and techniques without understanding how or why they worked or comprehending their physical or chemical composition. Before we go any further a definition has to be given for both Science and Technology because they are both different in their own right even though the two are almost indistinguishable. According to the Oxford Dictionary Technology can be defined as the knowledge or use of the mechanical arts and applied sciences, while Science can be defined as the branch of knowledge involving systematized observation and experiment. Science can be further divided into three separate categories; Pure, Applied and Natural Sciences. In addition technology is often defined as applied science, it is simply the application of scientific knowledge to achieve a specific human purpose, however, historical evidence suggests technology is a product of science.
Biogenetic engineering is the ability to change or modify a genome of an organism through the use of biotechnology. We use this in order to add a new gene to an organism that it would originally would not contain. This creates a better suited organism to adapt to any form of change it may have to deal with. Biogenetic engineering works by physically entering the organism’s genome and removing it and inserting the genome into another organism this allows the organism that had received the new trait to express the new code. The steps for genetic engineering is by first finding an organism that contains a trait that is desired, then scientist will extract the DNA, then once the gene has been extracted it goes through gene cloning, this is the process in which the gene is located and copied from the different of genes that had been extracted, and sometimes the desired gene will be modified so that it will be able to perform desirelly within the organism, the transgene, which is the new gene, will be inserted into the organism, once inserted scientist will allow for breeding in order to perfect the desired gene. Biogenetic engineering allows for the manual transport of genes from one organism to the next. The genes that we use for bioengineering are beneficial since we are able to perfect this genes for an unlimited amount of usage. Bioengineering also allows a single or a few desirable genes to be inserted into an organism rather than breeding which has at times undesirable traits that might not be as beneficial to the organism as the gene that is being inserted manually in bioengineering.
With the steady advancement of biotechnology in the future, there will be plenty of medicine that will be able to cure previously incurable diseases. In addition to this, the health care of sick patients will dramatically improve in the future.