Genetic and Environmental Contributions to Substance Abuse

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The question of nature vs. nurture has been the focus of many debates, especially within the discipline of psychological sciences. This paper will examine the views that exist regarding the importance of contributions to the risk of addiction, specifically, genetic (nature) vs. environmental (nurture) contributions through a review of the existing literature.

The nature-based view is that expression of addiction (phenotype) is based upon genetic predisposition (genotype). Numerous genetic studies on pedigree have been conducted over the years. The majority of the results of these studies indicate that monozygotic twins have higher concordance of addiction than dizygotic twins. More specifically, the more genes shared, the more similar the propensity for addiction.

Early studies genetic studies of addiction were family-based, which provided some initial clues regarding potential heritability of addictive disorders by examining the risk of substance abuse disorders by first-degree relatives of individuals who had either a substance abuse disorder or no substance abuse disorder. A study was conducted by Bierut et al. (1998), which produced results indicating that relative to a control individual, the siblings of alcohol-dependent probands had elevated rates of alcohol dependence. However, family designs are incapable of distinguishing whether the cause of familial similarity is genetic or environmental.

Adoption studies have also been utilized in addiction research related to genetics. Adoption studies involve the comparison of the concordance and correlation between offspring behavior (e.g. alcohol dependence) and the characteristics of both the biological and adoptive parents. Similarity observed between the o...

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...ictims. Child Abuse Negl, 21, 529–539.

McGue, M. (1999). The behavioral genetics of alcoholism. Curr Dir Psychol Sci, 8, 109–115.

McGowan-Anderson, L.J. (2006). Genetic Predisposition: Is the Human Organism Predisposed to Addictive Disorders? Journal of Addcitive Disorders. Retrieved from http://www.breining.edu.

Mullings, J.L., Hartley, D.J., & Marquart, J.W. (2004). Exploring the relationship between alcohol use, childhood maltreatment, and treatment needs among female prisoners. Subst Use Misuse, 39, 277–305.

Newcomb, M.D., Bentler, P.M. (1988). Impact of adolescent drug use and social support on problems of young adults: a longitudinal study. J Abnorm Psychology, 97, 64–75.

Osler, M., Nordentoft, M., & Andersen, A.M. (2006). Childhood social environment and risk of drug and alcohol abuse in a cohort of Danish men born in 1953. Am J Epidemiol, 163, 654–661.

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