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Human genetic modification ethical issue
Ethics of genetic engineering
Ethics of genetic engineering
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More than a decade after scientists have unraveled the human genome, there are attempts now by scientists across the globe to re-write it. Gene editing technologies have provided inexpensive ways to edit, delete, insert and modify genes in human cells. Correcting genetic defects sounds intriguing but people do worry about the extent of the possibilities. Some people are of the opinion that gene editing in embryos could benefit immensely as it would be able to eradicate terrible and life threatening genetic diseases even before the baby is born. Sounds good, doesn’t it? - But some people are of the impression that such kind of work though it sounds promising crosses the ethical boundaries because the genetic changes to these embryos which are …show more content…
For instance, altering developmental genes with CRISPR/Cas9 could help to reveal their functions. “Some questions about early human development can only be addressed by studying human embryos,” [5]
In contrast to Dr. Lovell some other Oxford bioethicists like Chris Gyngell and Julian Savulescu argue that there is a "moral imperative to research editing embryos." The Chinese research is important because it increases our understanding about some of the risks involved in targeting humans with current gene editing techniques. [4]
Even before the Chinese scientists work was published, a group of leading scientists, bioethicists met in California to figure out a plan so that gene editing technology would not be misused in unethical ways. They say gene editing in human embryos, eggs and sperms should stop however research on non-viable embryos which would not lead to viable pregnancies should be continued. Jennifer Doudna, a biochemist at University of California, Berkley whose work led to the development of CRISPR organized this meeting when she came to know CRISPR was being used by scientists to change DNA in human embryos. [6]
The not so supportive
SUMMARY: Director of the Ethics Institute, Ronald M. Green, in his article “Building Baby from the Genes Up” discusses why he thinks that genetically modifying babies genes is more beneficial than destructive. He begins his article off by mentioning a story of a couple who wishe to genetically modify their baby so that they could make sure the baby would not develop the long family line of breast cancer. Green then notifies the reader that no matter where they stand on the matter, genetically modifying babies is going to become more and more popular. Even the National Institute of Health is beginning to invest in technology that can be used to genetically modify human genes. He then explains how genetically modifying human genes can be beneficial,
Opposing Viewpoints offers unbiased opinions on the future of embryonic research as well as how they have currently been used to cure many diseases. In addition, the article specifies how developing ethical standards to ensure that the use of embryos remains moral, allows for science to remain ethical. Many of the topics mentioned in this viewpoint consider bioethics and remain consistent throughout. Essentially, the purpose of this article was to establish a middle ground between ethics and science.
Embryonic stem cells research has challenged the moral ethics within human beings simply because the point at which one is considered a “human,” is still under debate and practically incapable to make a decision upon.
...ns of a morally questionable nature. It is necessary that our practices remain ethical and that we uphold the value of a human life, as this is the cornerstone of human society. Embryonic stem cell research is one such operation that forces scientists, policy makers, and the larger society to define what constitutes a human life and to find an answer to the crucial question: Is it morally acceptable to violate the rights of a human life for the for the sake of medical progress?
If you could ensure that your future children would be healthy, would you? This is a trivial question because most parents would stop at nothing to ensure that their children are healthy. Human germ-line engineering may soon make it possible to alter the genome of human embryos—permanently changing the genetic blueprint for every cell in an embryo’s body. Through human germ-line technology we could eradicate many debilitating genetic diseases (e.g. Tay-Sachs disease, cystic fibrosis etc.), prevent cancer, and even increase the average life span. Human germ-line engineering is prenatal and produces genetically modified traits that can be passed along to subsequent generations—so the resulting genetic alterations are permanent. The utilization of human germ-line engineering technology, however, is analogous to Pandora’s Box. As attractive as it may seem, opening Pandora’s Box and unleashing human germ-line engineering technology could have severe consequences including negative medical or economic ramifications and a potential amplification of social and economic stratification. In this paper I will present views on the consequences and possible regulation of human germ-line engineering. I propose that the risks of human germ-line engineering technology outweigh the potential benefits and therefore this technology needs to be banned.
What do one think of when they hear the words “Designer Babies”? A couple designing their own baby of course, and it’s become just that. Technology has made it possible for there to be a way for doctors to modify a babies characteristics and its health. Genetically altering human embryos is morally wrong, and can cause a disservice to the parents and the child its effecting.
Picture a young couple in a waiting room looking through a catalogue together. This catalogue is a little different from what you might expect. In this catalogue, specific traits for babies are being sold to couples to help them create the "perfect baby." This may seem like a bizarre scenario, but it may not be too far off in the future. Designing babies using genetic enhancement is an issue that is gaining more and more attention in the news. This controversial issue, once thought to be only possible in the realm of science-fiction, is causing people to discuss the moral issues surrounding genetic enhancement and germ line engineering. Though genetic research can prove beneficial to learning how to prevent hereditary diseases, the genetic enhancement of human embryos is unethical when used to create "designer babies" with enhanced appearance, athletic ability, and intelligence.
Scientists have edited the DNA of non- viable embryos. It is argued that it’s the first step for parents being able to design their own children. Sarah Knapton (April 23) stresses the risks of Genetic Engineering by questioning the motivations of Genetic scientists. By stating that these genetic scientists want their names in a history books. Genetic engineering implies ethical issues and safety issues. Oxford professor conducted a test. 71 embryos survived and 54 were genetically tested. 28 were spliced and some of the contained a replacement genetic material. It was found that there was unexpected mutations that shouldn’t off been effected by the technique. However, the Chinese scientist states that the embryos were non-viable. Is this a safe practice if the researchers are contradicting themselves? Universal laws guided by ideologies that help promote the health and wellbeing of society using principles of equality and justice. Equality and justice are two values that need to be incorporated in this practice to make sure the focus on genetic engineering will be utilized for life saving reasons.
Genetic engineering depends on the location and analysis of genes on chromosomes and ultimately DNA sequencing. The early cartography of the genes used the principles of Mendelian genetics . It is assumed that alleles that are transmitted together side by side are located on the same chromosome : it is said that are connected or linkage . These genes form a bridging group - linkage group : are the same for gametes and are usually transmitted together , so they do not have independent distribution. Crossing-over occurring during meiosis may cause these alleles can be exchanged between the chromosomes of a homologous pair .
Gene therapy focuses on the replacement of defective genes with modified functioning genes. Many diseases are caused by a defective gene meaning the body is incapable of producing essential proteins or enzymes. In its simplest form, gene therapy aims to identify the defective gene and fix this gene with the replacement of a normal gene (Senn).
This paper goes over genetic engineering and how it is used today in the medical field as two types on humans, disabled genetic engineering and trait genetic engineering. This two types of genetic engineering are still debatable since they have to surpass many obstacles and laws. The sources gave statements from professionals and experts on genetic engineering, biomedical science, biomedical engineering, and human anatomy and physiology. The individuals gave their inputs on how they view genetic engineering on human beings.
A unanimous decision should be made on when to consider an embryo a human being that has morality. Until then I believe that the embryo is not close to a human life unless it has made it past the fourteen day period in which it is passed the twinning stage. So with this information I come to the conclusion that under specific regulations and laws, including the ones I mentioned in the summary, the cloning of embryos for biomedical research and obtaining stem cells should be deemed acceptable.
"The aim is to decrease the fear of a brave new world and to encourage people to be more proactive about their health. It [Gene therapy] will help humans become better physically and even mentally and extend human life. It is the future” (Hulbert). Dr. Hulbert, a genetic engineer, couldn’t be anymore right; more time, money, and research needs to be put into gene therapy and genetic engineering, since it can cure certain illness and diseases that are incurable with modern medicine, has fewer side-effects than conventional drugs or surgery, and allows humans to be stronger physically and mentally at birth. Gene therapy or genetic engineering is the development and application of scientific methods, procedures, and technologies that permit direct manipulation of genetic material in order to alter the hereditary traits of a cell, organism, or population (NIH). It essentially means that we can change DNA to make an organism better. Genetic engineering is used with animals and plants every day; for example with genetic...
Shortly after the groundbreaking discovery of the structure of DNA in 1953, the scientific world was essentially given the ability to alter the genetic sequence of any living organism using a process known as 'genetic engineering'. By definition, genetic engineering is 'the deliberate modification of the characteristics of an organism by manipulating its genetic material', it is quite simply an unnatural process which defies the ordinary course of nature. As of yet, no devastating or permanent damage has been done. However, the unpredictable nature and unknown consequences genetic engineering holds is more than enough reason to be cautious, as one mistake could have irreversible and catastrophic effects.
Human genetic engineering can provide humanity with the capability to construct “designer babies” as well as cure multiple hereditary diseases. This can be accomplished by changing a human’s genotype to produce a desired phenotype. The outcome could cure both birth defects and hereditary diseases such as cancer and AIDS. Human genetic engineering can also allow mankind to permanently remove a mutated gene through embryo screening, as well as allow parents to choose the desired traits for their children. Negative outcomes of this technology may include the transmission of harmful diseases and the production of genetic mutations.