Enhanced Gene Susceptbility 1 (EDS1)

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In plants, a large portion of disease resistance (R) genes code for leucine-rich-repeat (LRR) proteins which have amino-terminals and sites for nucleotides to bind (Falk et al. 1999). In Arabidopsis thaliana, a small flowering plant native to Europe and Asia, the functioning of these R genes is the result of having the Enhanced Gene Susceptibility 1 (EDS1) gene. Without a fully functioning EDS1 gene, the plant is more susceptible to Arabidopsis plant pathogens, such as fungal and bacterial pathogens, and autoimmune diseases (Falk et al. 1999). Therefore, it is critical that the EDS1 gene in Arabidopsis thaliana is present and does not have any mutations that could reduce its effectiveness in resisting pathogens (Østergaard and Yanofsky 2004). …show more content…

1999). Fungal pathogens that have been discovered in Arabidopsis plants, such as Rhizopus niveus, are made of several different types of lipases, including triacylglycerol lipases (Falk et al. 1999). Therefore, when an Arabidopsis plant encounters these fungal enzymes, the contained lipids are hydrolyzed by the EDS1 proteins and the fungal pathogen is

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