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The importance of vaccinations
Importance of immunization
The importance of vaccinations
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“Pathogens are infectious agents, such as a bacterium, virus, fungus or parasite, that cause disease when they colonize a host organism” (Pathogens). Pathogens have plagued societies time and time again. In the past people never had a way to fight them. But now the research into these deadly pathogens has brought many cures and vaccines to societies to protect them against these pathogens. Although the research into these diseases is not just to find cures and vaccines anymore, companies and organizations have recently started researching into GOF pathogens or gain-of-function pathogens. These pathogens have been modified to be transmitted faster, transmitted easier, or to be more lethal. The process of researching and enhancing pathogens has …show more content…
But is that result worth it if in the process millions of lives are lost by making the gain-of-function pathogens? And what limits the research to just for vaccines and cures? By creating gain-of-function pathogens not only are scientist creating cures, they are creating weapons. Weapons that are not limited to a certain area like explosives. They are not weapons that can be aimed and controlled. These new weapons could end our species if they become advanced enough. In September of 2001, “biologist Bruce E. Ivins single-handedly prepared and mailed deadly anthrax spores that killed five people” (Warrick). In this case one biologist killed five people with anthrax. Imagine if a terrorist group developed an enhanced stain of a pathogen and released it, millions of people could die. Soon this will actually be a possibility. With the research into these pathogens developing new deadlier strains has become a lot easier. Researching gain-of-function pathogens is undoubtedly highly dangerous, although outlawing the research permanently is not the right thing because it would limit vaccines and cures to diseases. The research into gain-of-function pathogens should just be restricted until the research can be guaranteed that it can be done safely. “395 reported ‘potential release events’ of ‘a biological agent or toxin that is considered to pose ‘a severe threat’ to human, animal or plant health’ occurred in U.S. …show more content…
The viruses scientist, in this field, work with have been enhanced to be more deadly and be transmitted easier. The research into enhanced pathogens could save lives because of creation of vaccines and cures for diseases and viruses, but in doing so risks the lives of everyone by risking exposing the diseases to the public and causing a pandemic. Researching gain-of-function pathogens should be restricted until it can be done safely without risking people’s lives. By researching enhanced pathogens scientists are enabling deadlier diseases and viruses to be created easier. By making these diseases and viruses easier to manufacture scientists are making it easier for people to develop them. Terrorists could use gain-of-function pathogens as biological weapons in terrorist attacks killing millions of people. In 2001 a deadly disease known as Anthrax was used to assassinate two United States Senators. No matter how many lives researching gain-of-function pathogens could save, the research should not be permitted. The research is not safe enough for it to be performed. In the last five years alone the United states has suspended this research three times because of safety risks and its threats to our national security. Overall this research has potential to be a great asset to medicine, but until it can be done safely gain-of-function research needs to be
This summer we had an opportunity to dive into the world of bioweapons, through Richard Preston’s novel The Demon in the Freezer. His book explored the colorful world of smallpox and its use as a biological weapon. Earlier this week we were graced with this authors present for an ACES event. He discussed some of the found topics in his book such as animal testing, what small pox is, and even its eradication. One of the great things we had the chance of vocalizing were our many opinions on the gloom associated with this intriguing disease.
The Demon in the Freezer by Richard Preston is an intriguing book that discusses the anthrax terrorist attacks after 9/11 and how smallpox might become a future bioterrorist threat to the world. The book provides a brief history of the smallpox disease including details of an outbreak in Germany in 1970. The disease was eradicated in 1979 due to the World Health Organization’s aggressive vaccine program. After the virus was no longer a treat the World Health Organization discontinued recommending the smallpox vaccination. In conjunction, inventory of the vaccine was decreased to save money. The virus was locked up in two labs, one in the United States and one in Russia. However, some feel the smallpox virus exists elsewhere. Dr. Peter Jahrling and a team of scientists at the U.S. Army Medical Research Institute of Infectious Diseases in Maryland became concerned terrorists had access to the smallpox virus and planed to alter the strain to become more resistant. These doctors conducted smallpox experiments to discover more effective vaccines in case the virus were released. Preparedness for a major epidemic is discussed as well as the ease with which smallpox can be bioengineered.
Guillemin, J. (2005). Biological weapons: From the invention of state-sponsored programs to contemporary bioterrorism Columbia University Press.
...in the fields of both science and medicine, future epidemics of any disease can be handled better. When a lethal disease begins to rampage a population, research on similar epidemics can help the world contain, cure, and prevent the disease to protect the world and its population.
our everyday lives bacteria is constantly surrounding us, some of the bacterium that we encounter are beneficial to us but then there are the ones that are severely detrimental to our health. The way that they effect a persons body can differ from person to person. Many of the “microscopic foes” are very resilient and have a very fast reproduction rate. Not only do they reproduce quickly they sometimes seem to outsmart our immune system and not allow our bodies to fight the infection making it almost impossible to stop them. One thing that a lot if people rely on is the assistance of prescription drugs to get them better but even the drugs are not being effective and we can’t stop the pathogens from invading our personal places such as work, home, school, or anywhere. Even though modern medicine is advancing the pathogens could still get the get the best of us. The scary thing is we never know when the next pandemic or epidemic is going to arise. All it needs is some ordinary microbe to swap genes with a deadly germ to produce a “super pathogen” and it could happen to anyone, anywhere, as it did to Jeannie Brown who is from “our neck of the woods”.
National Institute of Medicine (2007) Ethical and legal considerations in mitigating pandemic disease Retrieved from http://www.ncbi.nlm.nih.gov/books/NBK54163/
Polio eventually phased out from the development of an effective vaccine the late ‘60s and was officially eradicated from the United States in 1994. By the time it was pushed out of the Americas, Polio had swelled to over 350,000 recorded cases. Europe and America had always been on the developmental forefront, but prior to the Polio vaccination’s discovery, vaccines had only been created for mortality driven epidemics such as cholera, tuberculosis, bubonic plague, and diphtheria. All of the outbreaks had devastated large masses, and vaccines were created out of fear of further destruction. This way of thinking was challenged after Polio. Soon there was planning for the future, and there was work being done to halt deadly diseases. Protection against less harmful but just as significant viral infections were developing. These viral infections include the various strains of influenza we still see today. We started out with a significant advantage over other people and have only grown on it. Our superior technology, research, and access to information have helped us land to where we are to...
... much advancement in medicine has been created to improve life. The most common today is the cure for certain viruses. By simply taking a shot containing a vaccine, that took extensive amount of research and self-intuition, one can dramatically reduce their chance of the virus affecting them later on.
Disease has been known to humankind as the invisible killer for centuries. Plagues destroying towns, people dying for unexplainable reasons, and children dying all too soon. The miracle of modern medicine has permitted society to to have significant control over these terrifying invisible killer outbreaks. The vaccine is one of the greatest miracles of modern medicine. For example, the vaccine for the polio virus has virtually eliminated the incidences of polio in humans. “Vaccines represent a low-risk intervention administer according to a schedule in which there are currently no known acceptable alternatives.” (Opel et al. 2013). Vaccines protect the person who has been vaccinated from viruses and the more persons vaccinated the more
Hospital acquired infections are one of the most common complications of care in the hospital setting. Hospital acquired infections are infections that patients acquired during the stay in the hospital. These infections can cause an increase number of days the patients stay in the hospital. Hospital acquired infections makes the patients worse or even causes death. “In the USA alone, hospital acquired infections cause about 1.7 million infections and 99,000 deaths per year”(secondary).
Bacterial cells, like plant cells, are surrounded by a cell wall. However, bacterial cell walls are made up of polysaccharide chains linked to amino acids, while plant cell walls are made up of cellulose, which contains no amino acids. Many bacteria secrete a slimy capsule around the outside of the cell wall. The capsule provides additional protection for the cell. Many of the bacteria that cause diseases in animals are surrounded by a capsule. The capsule prevents the white blood cells and antibodies from destroying the invading bacterium. Inside the capsule and the cell wall is the cell membrane. In aerobic bacteria, the reactions of cellular respiration take place on fingerlike infoldings of the cell membrane. Ribosomes are scattered throughout the cytoplasm, and the DNA is generally found in the center of the cell. Many bacilli and spirilla have flagella, which are used for locomotion in water. A few types of bacteria that lack flagella move by gliding on a surface. However, the mechanism of this gliding motion is unknown. Most bacteria are aerobic, they require free oxygen to carry on cellular respiration. Some bacteria, called facultatibe anaerobes can live in either the presence or absence of free oxygen. They obtain energy either by aerobic respiration when oxygen is present or by fermentation when oxygen is absent. Still other bacteria cannot live in the presence of oxygen. These are called obligate anaerobes. Such bacteria obtain energy only fermentation. Through fermentation, different groups of bacteria produce a wide variety of organic compounds. Besides ethyl alcohol and lactic acid, bacterial fermentation can produce acetic acid, acetone, butyl alcohol, glycol, butyric acid, propionic acid, and methane, the main component of natural gas. Most bacteria are heterotrophic bacteria are either saprophytes or parasites. Saprophytes feed on the remains of dead plants and animals, and ordinarily do not cause disease. They release digestive enzymes onto the organic matter. The enzymes breakdown the large food molecules into smaller molecules, which are absorbed by the bacterial cells. Parasites live on or in living organisms, and may cause disease. A few types of bacteria are Autotrophic, they can synthesize the organic nutrients they require from inorganic substances. Autotrophic bacteria are either photosynthetic or Chemosynthetic. The photosynthetic bacteria contain chlorophyll that are different from the plant chlorophyll. In bacterial photosynthesis, hydrogen is obtained by the splitting of compounds other than water.
... because of the need to fight back against infectious diseases. As vaccine development progresses into the 21st century, it’s important to build on the experience and knowledge generated in the past, in an effort to surpass the limita-tions that currently hamper the development of new and more effective vaccine technologies.
Infectious diseases are the disorders caused by organisms such as bacteria, viruses, fungi or parasite who live both inside and outside our bodies and are normally helpful but can cause infectious diseases to the human (body) system under certain conditions. And for a disease to be infectious, there is what is called ‘’chain of infection’’ that takes place before. And this can be seen in the below diagram:
In the 1960s, doctors in the United States predicted that infectious diseases were in decline. US surgeon Dr. William H. Stewart told the nation that it had already seen most of the frontiers in the field of contagious disease. Epidemiology seemed destined to become a scientific backwater (Karlen 1995, 3). Although people thought that this particular field was gradually dying, it wasn’t. A lot more of it was destined to come. By the late 1980s, it became clear that people’s initial belief of infectious diseases declining needed to be qualified, as a host of new diseases emerged to infect human beings (Smallman & Brown, 2011).With the current trends, the epidemics and pandemics we have faced have created a very chaotic and unreliable future for mankind. As of today, it has really been difficult to prevent global epidemics and pandemics. Although the cases may be different from one state to another, the challenges we all face are all interconnected in this globalized world.
In conclusion, it is clear that a biological weapon is wrong. When Saddam Hussein threatened to turn the Persian Gulf War into “the mother of all wars” the world shook with the possible implications. The United States managed to divert the course of the war such as this did not happen. In other situation these results have not been as successful, unfortunately, and many people have suffered and died. I hope that civilization is moving towards total illumination of biological weaponry.