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Ethical issues concerning human subject experimention pdf
Experimentation on animals is justified or not
Human experimentation advantages and disadvantages
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Denis Diderot once said, “There are three principal means of acquiring knowledge... observation of nature, reflection, and experimentation. Observation collects facts; reflection combines them; experimentation verifies the result of that combination.” What Denis Diderot talks about is logical when trying to obtain information on a certain subject, and this applies to experiments performed on humans. When individuals think of human experimentation, unethical and immoral are sometimes the first words the pop into their brain. Human experimentation is beneficial in the sense that it can it can provide factual information, advancements in the medical field, and how human experimentation will be beneficial in the future. To begin with, human …show more content…
The side effects are also taken into consideration in order to see if this medicine is safe enough to release to the public. In fact, according to Anthony Wrigley, author of the ‘Human experiments- the good, the bad, and the ugly’ states that “…English physician Edward Jenner’s development of the smallpox vaccine in 1796, where he injected an eight-year-old child with the pus taken from a cowpox infection and then deliberately exposed her to an infected carrier of smallpox.” Even though Edward Jenner’s experiment on a eight-year-old child seemed unethical, it provided the cure to smallpox. While taking a chance and injecting pus into the child, Edward Jenner created a vaccine that would cure many individuals. With the cure that Edward Jenner created, millions would benefit off of him. With the data and information that Edward Jenner had acquired, he test was a success, and many individuals would benefit off this vaccine that man has created. Many individuals will say that unethical practice can come into practice again, but there are organizations, such as Research ethic committees, that keep a close eye on experiments being conducted on people. For instance, in “Human …show more content…
Human experimentation can help in the future by being able to provide vaccines to harmful diseases. This can help society because it is not harming or deadly in any ways because humanity has a way to counter the sickness. David B. Resnik talks about the “social benefits” that human experimentation has and “…Phase I clinic trials on healthy subjects can be justified on the grounds that they are essential to developing new treatments that will help people who have the target diseases.” Being able to create treatments that can cure incurable diseases is one of the goals of human experimentation. The ethical part of performing tests on people is to get results that will better them. Finding cures to illnesses such as AIDS, cancer, and Ebola is one of the main reasons that doctors and scientists implement the examinations. They are finding a cure that will benefit humanity as a whole, and there are individuals who call these tests unethical. Though there are individuals who are calling these experiments corrupt, they may have benefited off of it. Many pills and shots were made because of experiments, and it will always be to better individuals’ lives. For example, in the future, it is possible that there is going to be a cure for AIDS, cancer, and Ebola. Many tests will be conducted on humans who have these diseases, but there will be a cure because of experiments. They will better the future in helping
The study took advantage of an oppressed and vulnerable population that was in need of medical care. Some of the many ethical concerns of this experiment were the lack of informed consent, invasion of privacy, deception of participants, physical harm, mental harm, and a lack of gain versus harm. One ethical problem in this experiment was that the benefits did not outweigh the harm to participants. At the conclusion of the study there were virtually no benefits for the participants or to the treatment of syphilis. We now have
Although not as strictly addressed, there is still a schism when it comes to the matters of experimentation involving animals. Those in opposition of it see it as being against the will of the animal, because animals have no say in the matter. However, through animal experimentation there has been vast medical advances in hospitals and veterinarians , research has led to cures for various diseases that would normally take many more years to cure, and the use of animals is highly ethical considering what could be the alternative, although there is progress being made to change these measures. This is how animal experimentation is of use to society for humans and animals.
Albert Sabin, the developer of the polio vaccine once said, “Without animal research, polio would still be claiming thousands of lives each year.” Polio is a deadly disease caused by a virus that spreads from person to person. This infectious disease renders the brain and spinal cord helpless while also ensuring a permanent case of paralysis to the victim. According to the Centers for Disease Control and Prevention, “…13,000 to 20,000 para-lytic cases were reported annually,” before the 18th century. After the introduction of the polio vaccine, “…a total of 2,525 paralytic cases were reported, compared with 61 in 1965.” This dramatic decrease in the prominence of the polio disease can only be attributed to the success of animal testing. Animal experimentation is used in the research of genetics, drug testing, biology, toxicity testing, cosmetic testing, and many other fields. Despite all of its beneficial traits, animal testing has been wildly controversial over the past decades because of its perceived unethical treatment towards animals. Although animal testing may be deemed unethical by many, it is a form of medical testing that has not only saved lives but has also greatly revolutionized the medical world.
Point of view: Web. 14 February 2016. The article provides specific examples of illnesses and diseases which have been cured by animal testing that both humans and animals have benefitted from. This supports my topic of animal experiments being used for medical advancements. Pointing out that law often requires that products be tested before being sold to the public, George and Wagner additionally help prove my claim that product testing is a purpose of animal experimentation.
Putting aside the countless claims that animal experimentation is unethical and should be banned, it is incredibly necessary and useful for mankind. Experimenting on humans is inhumane and completely immoral, while animals that do not function in the same way humans do should be used in medical research and to test the safety of various products. If animal testing were illegal, how would worldly corporations determine the safety of products? Surely the valuable lives of human beings are not essential to risk, hence the reason that animal experimenting is necessary. In addition, medical research would be in great jeopardy if were animals were not permitted to be experimented on. Medical industries have already come so far in treating multiple ailments due to the tests performed on animals. Alas, it is safe to say that for the continued thriving of our society, forbidding animal experimentation would be detrimental.
So it’s understandable when people like Peggy Carlson say that animal testing is wrong and that we should not use it. In her article Carlson says, “In the case of the polio vaccine, misleading animal experiments detoured scientists away from reliable clinical studies thereby, according to Dr. Sabin himself, delay the initial work on polio prevention” (Page 160) Something that Carlson has to understand is that animal testing is not the perfect solution, but it is required. There will be mistakes but it is the right course of action.
When you here the words ‘human experimentation‘, you think lab coats, mad scientists, and monsters like Frankenstein. But the reality of it is much more gruesome. People just like you and me were used like guinea pigs. In many cultures, a doctor is thought of as a healer; a person who lives to save others. That was not the case of the physicians that severed for the labor camps in Poland. Human experimentation is sadly a horrific thing of our world’s past and is most commonly related to in the stories of testing taking place in Nazis concentration camps of World War Two. Nazis doctors took innocent people and performed grueling experiments on them for three specific reasons (United States Holocaust Museum).
Animal testing is important to ensure the safety of a variety of products, specifically pharmaceuticals, vaccines, and medical devices used for surgery and other treatments. It has also been used throughout history for various purposes. Once an unregulated practice, today there are laws, regulations, and requirements associated with the ethical use of animal models. In the United States, animal studies are now required before moving on to clinical trials. Legalities aside, controversy still arises between scientists, and public opinion can vary from unconcerned to extreme. The practice of vaccination is an important part of maintaining public health, and it has proven to be beneficial to both humans and animals. In regard to vaccine development, animal testing during the pre-clinical stage seems to be a necessary part of the process. The growth of technology may provide us with potential alternatives to animal testing, and the search for such alternatives is of ethical importance.
On the other hand, animal experimentation has brought us so far, and without it, we would not be where we are today. Losing animal experimentation would cause many people to lose jobs, and we would not advance in medical technologies. No one would be guaranteed safety when using a product designed to help them. It would do more harm if we stopped animal experimentation. Plus, it's not only designed to help humans, but it helps animals as well. So technically we are helping both animals and humans. Over all its very important to test on animals to get what we need, in addition there isn't much else scientists can test on.
In the United States, the basis for ethical protection for human research subjects in clinical research trials are outlined by the Belmont Report developed in the late 1970’s. This document, published by the Nation Commission for the Protection of Human Subjects of Biomedical and Behavioral Research, highlights three important basic principles that are to be considered when any clinical trial will involve human research subjects. They are; respect for persons, beneficence, and justice. (Chadwick & Gunn, 2004)
Looking beyond the Nuremberg Code and applying it to modern medical research ethics, there are many challenges that it poses. Many have argued that the Code tries to provide for all unforeseen events, which restricts the researcher by requiring him to anticipate every situation, demanding the impossible. The most important contribution of the Code is the first principle, which says that voluntary consent of the human subject is absolutely essential. The subject involved should have legal capacity to give consent, should have free power of choice, as well as sufficient knowledge and comprehension of the experiment. This restricts that populations upon which some experiment may be conducted, since many do not have “legal capacity”. For instance, studies of mental illness and children’s diseases have been curtailed because neither of these populations has the legal capacity to give consent. Another group of people, prisoners, are never really able to give voluntary consent since they might be enticed by financial rewards, special treatment, and the hope of early release in exchange for participating in the human experimentation projects. British biostatitcian Sir Austin Bradford Hill also questioned whether it was important to inform a research subject who was receiving a placebo since it does...
For my debate on human experimentation I believe that it is unethical . One of the reasons is because when being tested on you don't know what's going to happen. Also because you can get seriously hurt and can even die. When being experimented on you can get bad rashes,diseases, permanent scars,and it can even make you go crazy,like one of our worst experiments called the monster study.
Unethical experiments have occurred long before people considered it was wrong. The protagonist of the practice of human experimentation justify their views on the basis that such experiments yield results for the good of society that are unprocurable by other methods or means of study ( Vollmann 1448 ).The reasons for the experiments were to understand, prevent, and treat disease, and often there is not a substitute for a human subject. This is true for study of illnesses such as depression, delusional states that manifest themselves partly by altering human subjectivity, and impairing cognitive functioning. Concluding, some experiments have the tendency to destroy the lives of the humans that have been experimented on.
However, some people believe that animal testing is beneficial in various ways. Those people that see animal testing as beneficial think that without animals, medical developments would not be where it is today. (Animal Testing) It has helped us to find and ensure the safety of drugs and treatments to improve health and medicine such as; open heart surgery, organ transplants, effective insulin, vaccines for deadly diseases and others. It is the most accurate way to learn the effects of substances in a living body. (Animal Testing) Another reason they see it benefi...
Throughout the years animal rights groups and organizations have frowned upon animal experiments. Animal testing has been thought to be inhumane and cold-hearted to animals. Because of these accusations medical researchers have to suffer threats from individuals and the media. If animal testing weren’t allowed would that be a drawback in advancement in medical research? Animal testing is beneficial to people because these trails lead to improvements in medical research. Animal experiments have led to finding new cures and vaccines to fatal illnesses. Because animal experiments are helpful in making vaccines to prevent these sicknesses, these trails are the reason so many lives are saved. Animal testing is very necessary and useful to people, but animal rights groups believe that these trails doesn’t benefit humanity. According to Ellen Paul, “Breakthroughs in treating injuries, like practically all medical advances, depend upon experimentation on animals.” Animal experiments have given way to many new instruments to fight against diseases like cancer (Paul). For example, mice and other rodents contributed to scientists developing new tools for fighting different forms of cancers (Paul). Animal testing has helped science in many ways, but animal organizations like People for the Ethical Treatment of Animals (PETA) believe that these experiments are cruel to animals. Even though most animals endure some sort of pain during these experiments, the results are very beneficial to people.