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Typhoid Case Study
Pathogenesis of typhoid fever
Thesis of typhoid fever
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So, what is typhoid fever?
“Typhoid fever is an infection that causes diarrhea and a rash -- most commonly due to a type of bacteria called Salmonella typhi (S. typhi). This bacterium spreads through contaminated food, drink, or water. They travel into your intestines, and then into your bloodstream, where they get into your lymph nodes, gallbladder, liver, spleen, and other parts of your body”1.
Typhoid fever originated around 430-424 BC which was during the golden Age of Pericles. It is spread on the chances of it being this disease, but DNA sequences show similar bacterium responsible for typhoid fever2. Early symptoms to look out for are fever, general ill feeling, and abdominal pain. A high fever and severe diarrhea occur, as the disease gets worse. Some people with typhoid fever develop a rash called "rose spots," which are small red spots the cover the surface of the body1.
Why target this disease?
Typhoid fever is contagious.
In 1907, Mary Mallon became the first American carrier to be identified and traced with typhoid fever. “She was a cook in New York and became closely related to fifty-three cases and three deaths. Public Health authorities told Mary to give up working as a cook or have her gallbladder removed. Mary quit her job but returned later under a false name. She was detained and quarantined after another typhoid outbreak”2.
Some people who get this the disease are prone to becoming carriers of the bacteria. They can continue to release S. typhi in their urine and or stool for years, likewise spreading the disease. They might never even know they are causing such harm, but essentially this is one ...
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...hospital systems. The main solution for this would be funds through charity and creating an organization to develop such projects that have already been instituted all over the world like Uganda, Central Africa, and Heidi. Finances for this would come from the aid of people with the ability to give any money they feel is worthy of saving a persons life. Other solutions to this may include fundraising and donations, all in the name of the cure of this disease and all diseases alike.
Footnote
Although vaccines and antibiotics seem promising as a cure for typhoid fever, they have not completely eradicated the disease.
References
1MedlinePlus website http://www.nlm.nih.gov/medlineplus/ency/article/001332.html
2NewsMedical website http://www.news-medical.net/health/Typhoid-Fever-History.aspx
3WebMD website http://www.webmd.com/a-to-z-guides/typhoid-fever?page=2
Typhoid fever is a systemic infection caused by the gram-negative organism Salmonella typhi. It is transmitted through fecal-oral or urine-oral route by either direct or indirect contact of the carrier’s or infected individual’s feces or urine. Humans are the only source of this organism. Ingestion of
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The Cholera Epidemic of 1873 in the United States. 43d Cong. , 2d Sess. House. The.
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In 1870, Mary Mallon, the carrier of typhoid was being born. Before they were discovering her disease she was infecting fifty-one people. This goes to show that discovery is somewhat beneficial when it comes to the spreading of illness. Being stated on page two hundred and fifty-nine “Mallon was brought- literally kicking and screaming- to the Riverside Hospital for Communicable Diseases on North Brother island”, here is where the examining of “Typhoid Mary” began. Generally, if the hospital wasn’t discovered then the cure for typhoid fever would potentially be nonexistent.
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Preventing diseases is every countries’ responsibility, whether they are poor or rich. Poor countries lack the knowledge and the money to gain, and expand medical resources. Therefore, many people are not been able to be cured. For wealthy countries, diseases are mutating at incredible speeds. Patients are dying because drug companies do not have enough data to produce vaccines to cure patients. When developed countries help poor countries to cure their people, the developed countries could help underdeveloped countries. Since developed countries can provide greater medical resources to poor countries, people living in the poor countries could be cured. As for the developed countries, they can collect samples from the patients so that the drug companies can produce new vaccines for new diseases. When trying to cure diseases, developed countries and poor countries would have mu...