Chronic Bladder Disorder

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Chronic Bladder Disorder There are few telltale signs of what Shelly Gregory copes with on a daily basis. On closer observation, one may notice the odd way she holds the right side of her abdomen when she walks or the way she tilts her body to the side when she sits on a chair for too long. To people around her, Gregory, a 35-year-old mother of two daughters, may pass as healthy. But only those in her inner circle, including her husband and children, truly understand the pain she has to endure. “When I’m having a really bad day, it feels like there is glass in my bladder and it’s bleeding and there’s nothing I can do to stop it,” Gregory said. “It hurts so much that it makes me think that my heart is going to explode.” Gregory is one of the more than 700,000 people in the U.S. – 90 percent of them women –who is battling interstitial cystitis, a chronic disorder characterized by inflammation of the bladder that causes urinary frequency and urgency and pelvic pain. There has been relatively little advancement made on this condition since the first written reference to interstitial cystitis was made in 1836. More than a century later, there are still few clear answers to what causes this multifaceted disease or how to treat it effectively. According to epidemiological studies conducted in 1997, the disease typically afflicts white, educated women in their early to mid-40s. The spectrum of symptom severity, however, can vary from person to person. Some people experience the urge to urinate (up to 70 times per day), while others endure bladder pressure or, in severe cases, unremitting bladder pain. When doctors perform a cystoscopy – a procedure that involves inserting a thin scope inside the bladder – on certain interstitial cystitis patients they can see evidence of the disease: mucosal hemorrhaging or Hunner’s ulcers that bleed when the bladder is filled beyond capacity. People with IC have small capacity bladders that hold less than 300 ml, or approximately 1 cup. Gregory said her bladder pain started in 1992 when she developed a blood clot after giving birth to her daughter. Five years later she found out that interstitial cystitis, not the blood clot, was the culprit. Dr. Robert Moldwin, a national expert on interstitial cystitis and director of the Interstitial Cystitis Center at Long Island Jewish Medical Center in Hyde Park, N.Y., said despite its prevalence, doctors often misdiagnose interstitial cystitis because patients can perceive pain in one or more areas of the pelvis.

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